ANEW MEDICAL, INC. (“ANEW” or “the Company”) (NASDAQ: WENA) a US-based biotechnology company focused on developing cell- and gene-based treatments to affect aging and age-related diseases, announces the grant and issuance of patent number HK1259628 protecting the development of novel genetic approaches for the treatment of neurodegenerative diseases to include Alzheimer’s disease, Parkinson’s diseases and amyotrophic lateral sclerosis (“ALS”).

The Company previously announced that it had been granted this key patent in China (Patent No. CN 117126829A) for the use of ANEW’s Klotho protein and Klotho gene delivery and expression systems in the treatment of cognition, memory and neurodegenerative diseases. This intellectual property was licensed by ANEW from UNIVERSITAT AUTÒNOMA DE BARCELONA (UAB) and INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS (ICREA) in Barcelona, Spain on an exclusive worldwide basis.

Dr. Joseph Sinkule, the Founder and CEO of ANEW, stated: “With intellectual property protection in Hong Kong, Beijing, Shanghai, and throughout the Chinese market for our innovative way of treating neurodegenerative diseases like Alzheimer’s diseases (“AD”), identifying clinical trial sites and corporate partners to evaluate the efficacy and safety of our product candidates is very important to ANEW.”

Dr. Sinkule continued: “The patents, comprising the secreted form of the human Klotho protein (“s-KL”) being delivered as a protein or by delivery of a sequence of the human gene that makes the protein in the body, are projected to be a major advance in how we treat or prevent the progression of these neurologic diseases. We are particularly excited about the preclinical results and plan to begin human testing in late 2025.”

The aging population in China is affected by the same age-related diseases we are fighting in the US and Europe. According to a recent report, China has the highest number of Alzheimer's patients in the world, with nearly 10 million people aged 60 and older suffering from the disease. Additionally, Asia in general is experiencing the fastest growth in the elderly population is taking place. Japan is considered a “super-aging” country, and the number of people with AD in Japan is expected to reach approximately 6.5–7 million by 2025, very similar to the prevalence of AD in the U.S. (approximately 7 million cases). AD and AD-associated dementia are very common in Western Europe and Finland, with North America following close behind. While AD is least common in Sub-Saharan Africa, African-Americans in the U.S. are about twice as likely to have Alzheimer's disease or other forms of dementia as Caucasian and Hispanic Americans.

About ANEW MEDICAL, INC.:ANEW MEDICAL, INC. (NASDAQ: WENA) is a biopharmaceutical company specializes in the development of patented, novel disease-modifying technologies targeting the brain and central nervous system (CNS) that are seen as key developments in treating neurodegenerative and age-related disorders. The Company obtained exclusive worldwide rights to platform technologies and knowhow to develop cutting edge protein, gene and cell therapies to treat age-related pathologies such as Alzheimer’s and Parkinson’s Disease, ALS, multiple sclerosis and rare neurodegenerative diseases. The company is managed by a team of individuals and advisors who are highly experienced in biopharmaceutical product development and commercialization.

For more information, contact:Eric BoydInvestor RelationsEmail: IR@anewmeds.com

Forward-Looking Statements:This press release contains forward-looking statements. These statements are made under the “safe harbor” provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements generally are identified by the words “believe,” “project,” “expect,” “anticipate,” “estimate,” “intend,” “strategy,” “future,” “opportunity,” “plan,” “may,” “should,” “will,” “would,” “will be,” “will continue,” “will likely result,” and similar expressions. Without limiting the generality of the foregoing, the forward-looking statements in this press release include descriptions of the Company’s future commercial operations. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this press release, such as the Company’s inability to implement its business plans, identify and realize additional opportunities, or meet or exceed its financial projections and changes in the regulatory or competitive environment in which the Company operates. You should carefully consider the foregoing factors and the other risks and uncertainties described in the documents filed or to be filed by the Company with the U.S. Securities and Exchange Commission (the “SEC”) from time to time, which could cause actual events and results to differ materially from those contained in the forward-looking statements. Copies of these documents are available on the SEC’s website, www.sec.gov. All information provided herein is as of the date of this press release, and the Company undertakes no obligation to update any forward-looking statement, except as required under applicable law.

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