Targeted Genetics Corporation (NASDAQ: TGEN) will report its fourth quarter and year-end 2008 results after the close of the financial markets on Tuesday, March 31, 2009. Following the announcement, management will host a conference call and webcast discussion of the financial results and provide a general corporate update beginning at 5:00 p.m. Eastern Time / 2:00 p.m. Pacific Time. You may access the live webcast via the "Events" section found on the homepage of the Company's website at: www.targetedgenetics.com or via telephone at 800.866.5341 (domestic) or 303.262.2143 (international).

Replay Access

Webcast replay will be available for approximately 30 days at www.targetedgenetics.com; telephone replay will be available following Wednesday's call at approximately 5:00 p.m. PT through 11:59 p.m. PT, Friday, May 1, 2009, by calling 800.405.2236 (domestic) or 303.590.3000 (international); pass code 11128979#.

About Targeted Genetics Corporation

Targeted Genetics Corporation is a biotechnology company committed to the development of innovative therapies for the prevention and treatment of diseases with significant unmet medical need. A key area of focus for Targeted Genetics is applying its proprietary Adeno-Associated Virus (AAV) technology platform to deliver genetic constructs to increase gene function or silence gene function. Targeted Genetics' lead product development efforts target ocular and neurological indications, two therapeutic areas where AAV delivery may have competitive advantages over other therapeutic modalities. To learn more about Targeted Genetics, visit its website at www.targetedgenetics.com.

Investor and Media Contact: Stacie D. Byars SDByars Communications, LLC 206.660.2588 Email Contact

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