FSD Pharma Begins Phase 1 In-human Safety and Tolerability Study of Ultra Micro-Palmitolylethanolamide (PEA)
09 3월 2020 - 9:30PM
Business Wire
FSD Pharma Inc. (Nasdaq: HUGE) (CSE: HUGE) (FRA: 0K9A) (“FSD
Pharma” or the "Company") today announced receipt of approval
from the Ethics Committee of the Alfred Hospital, part of the
Alfred Health group of hospitals serving the state of Victoria in
Australia, to initiate a Phase 1, randomized, double-blind,
placebo-controlled study to evaluate the safety, tolerability and
pharmacokinetics of single and multiple ascending doses of
ultra-micronized-PEA in normal healthy volunteers.
The study is now underway at Alfred Hospital in Melbourne and is
being led by principal researcher Jason Lickliter, MD, Chief
Medical Officer of Nucleus Network, Australia’s largest and most
experienced Phase 1 clinical research organization.
"The initiation of this Phase 1 in-human safety and tolerability
clinical study of ultra-micronized formulation of PEA is a
ground-breaking milestone for our company as we stride forward to
find novel anti-inflammatory treatment outcomes for patients by
targeting the CB2 receptors of the endocannabinoid system," said
Raza Bokhari, MD, Executive Co-Chairman & CEO. "I must
congratulate Dr. Edward Brennan, President of FSD Pharma’s
BioSciences Division, and his very qualified team on delivering
this milestone on schedule. Dr. Brennan's decades of experience in
drug development is very noteworthy, and I share his confidence
that this Phase 1 in-human study based on U.S. FDA-approved
guidelines will produce favorable data. The study would validate
considerable scientific literature already published, over the
years, in the European Union, that claims safety and tolerability
of micro-PEA, which is being dispensed in Italy and Spain as a
prescription-based medical food supplement since 2004.”
About FSD Pharma
FSD Pharma is a specialty biotech pharmaceutical R&D company
focused on developing over time a robust pipeline of FDA-approved
synthetic compounds targeting the endocannabinoid system of the
human body to treat certain diseases of the central nervous system
and autoimmune disorders of the skin, GI tract, and the
musculoskeletal system.
Through its acquisition of Prismic Pharmaceuticals in Q2 2019,
FSD Pharma is also making an effort to help address the opioid
crisis by developing opioid-sparing prescription drugs utilizing
the micronized formulations of palmitolylethanolamide (PEA). The
Company has Phase 1 first-in-human safety and tolerability trials
for its lead candidate, PP 101 micro-PEA underway in Australia.
FSD’s wholly-owned subsidiary, FV Pharma, is a licensed producer
under Canada’s Cannabis Act and Regulations, having received its
cultivation license on October 13, 2017, and its full Sale for
Medical Purposes license on June 21, 2019. The Company is licensed
to cultivate cannabis in approximately 25,000 square feet of its
facility in Cobourg, Ontario.
Forward-Looking Statements
Neither the Canadian Securities Exchange nor its regulation
services provider accept responsibility for the adequacy or
accuracy of this release.
Certain statements contained in this press release constitute
“forward-looking information” and “forward-looking statements”
within the meaning of applicable Canadian and U.S. securities laws
(collectively, “Forward-Looking Information”). Forward-Looking
Information includes, but is not limited to, information with
respect to FSD Pharma’s strategy, plans or future financial or
operating performance, receipt of any U.S. Food and Drug
Administration (“FDA”) approvals, development of any FDA approved
synthetic compounds, the successful treatment of diseases by such
compounds, the ability to address the opioid crisis, the
development of opioid sparing prescription drugs utilizing the
micronized formulations of palmitolylethanolamide (“PEA”), the
intention and timing of the initiation of Phase 1 first-in-human
safety and tolerability trials for PP 101 micro-PEA, maintenance of
FSD Pharma’s Cannabis Act License, the ability to cultivate and
sell cannabis produced in FSD Pharma’s facility, the progress and
funding of the CBD Research Project, the ability and technical
feasibility of algae being utilized to produce pharmaceutical-grade
cannabinoids and the ultimate success of the CBD Research Project,
the production of prescription drugs that can treat diseases
affecting the central nervous system, and related royalty fees. The
use of words such as “budget,” “intend,” “anticipate,” “believe,”
“expect,” “plan,” “forecast,” “future,” “target,” “project,”
“capacity,” “could,” “should,” “focus,” “proposed,” “scheduled,”
“outlook,” “potential,” “estimate” and other similar words, and
similar expressions and statements relating to matters that are not
historical facts, or statements that certain events or conditions
“may” or “will” occur, are intended to identify Forward-Looking
Information and are based on FSD Pharma’s current beliefs or
assumptions as to the outcome and timing of such future events.
Such beliefs or assumptions necessarily involve known and unknown
risks and uncertainties that could cause actual results to differ
materially from those expressed or implied in such Forward‐Looking
Information. Forward‐Looking Information is not a guarantee of
performance. The Forward-Looking Information contained in this
press release is made as of the date hereof, and FSD Pharma is not
obligated to update or revise any Forward-Looking Information,
whether as a result of new information, future events or otherwise,
except as required by law. Because of the risks, uncertainties and
assumptions contained herein, investors should not place undue
reliance on Forward Looking-Information. The foregoing statements
expressly qualify any Forward-Looking Information contained
herein.
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version on businesswire.com: https://www.businesswire.com/news/home/20200309005453/en/
For further information: Sandy Huard, Head of
Communications, FSD Pharma, Inc. sandy@fsdpharma.com (647) 864-7969
Investor Relations IR@fsdpharma.com www.fsdpharma.com Or
LHA Investor Relations Sanjay M. Hurry shurry@lhai.com (212)
838-3777
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