DPII Discovery Partners

CAMBRIDGE, Mass., Aug. 28 /PRNewswire/ -- Infinity Pharmaceuticals, Inc. today announced that Discovery Partners International, Inc. (NASDAQ:DPII), or DPI, has filed a supplement to the Proxy Statement/Prospectus (part of the S-4 Registration Statement) describing the collaboration announced today between Infinity Pharmaceuticals and MedImmune, Inc. to jointly develop and commercialize novel small molecule cancer drugs targeting Heat Shock Protein 90 (Hsp90) and the Hedgehog cell-signaling pathway. In preclinical studies, Hsp90 and the Hedgehog pathway appear to be implicated in the growth and survival of a broad range of blood-related and solid tumor types. IPI-504, the most advanced of the drug candidates included in the collaboration agreement, is an Hsp90 inhibitor that has thus far been studied in two disease-focused Phase I trials. The merger is subject to customary closing conditions, including the approval of both companies' stockholders. DPI's shareholders of record on August 1, 2006 will vote on the merger at a special meeting of stockholders at 1:00 p.m. PDT, on Tuesday, September 12, 2006, at the offices of Cooley Godward LLP, 4401 Eastgate Mall, San Diego, Calif. Infinity's stockholders of record on July 28, 2006 will vote on the merger at a special meeting of stockholders of Infinity at 1:00 p.m. EDT on Tuesday, September 12, 2006, at the offices of Wilmer Cutler Pickering Hale and Dorr LLP, 60 State Street, Boston, Mass. The proxy statement/prospectus supplement and the S-4 Registration Statement may be accessed online on the SEC's website, http://www.sec.gov/, on the "Investor Relations" page of DPI's website at http://www.discoverypartners.com/, or on Infinity's website at http://www.ipi.com/. Assuming stockholder approval of the merger and the other matters set forth in the Joint Proxy Statement/Prospectus, immediately following the merger, DPI will change its name to Infinity Pharmaceuticals, Inc. and the new company's common stock will trade on the NASDAQ National Market under the symbol "INFI." DPI's current ticker symbol, "DPII," will become inactive after closing. About Infinity Pharmaceuticals, Inc. Infinity is an innovative cancer drug discovery and development company that is seeking to leverage its strength in small molecule drug technologies to bring important new medicines to patients. The company recently announced a definitive agreement to merge with Discovery Partners International, Inc. (NASDAQ:DPII). Additional Information about the DPI-Infinity Merger and Where to Find It In connection with the proposed merger between Discovery Partners International, Inc. (DPI) and Infinity, on August 7, 2006, DPI filed an amended registration statement on Form S-4 that contains a proxy statement/prospectus, which registration statement has been declared effective by the SEC. Investors and security holders of DPI and Infinity are urged to read the proxy statement/prospectus (including any amendments or supplements to the proxy statement/prospectus) regarding the proposed merger because it contains important information about DPI, Infinity and the proposed merger. Security holders will be able to obtain a copy of the proxy statement/prospectus, as well as other filings containing information about DPI and Infinity, without charge, at the SEC's Internet site (http://www.sec.gov/). Copies of the proxy statement/prospectus can also be obtained, without charge, by directing a request to Discovery Partners International, Inc., 9640 Towne Centre Drive, San Diego, CA 92121, Attention: Investor Relations, Telephone: (858) 455-8600. Participants in the solicitation DPI and its directors and executive officers and Infinity and its directors and executive officers may be deemed to be participants in the solicitation of proxies from the stockholders of DPI in connection with the proposed merger of DPI with Infinity. Information regarding the special interests of these directors and executive officers in the merger transaction is included in the proxy statement/prospectus referred to above. Additional information regarding the directors and executive officers of DPI is also included in DPI's proxy statement for its 2006 Annual Meeting of Stockholders, which was filed with the SEC on April 6, 2006. This document is available free of charge at the SEC's website (http://www.sec.gov/) and from Investor Relations at DPI at the address described above. Forward-Looking Statements This release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include statements regarding the proposed transaction and the trading of the combined company's shares on the NASDAQ National Market. Factors that may cause actual results to differ materially include the risk that DPI and Infinity may not obtain the requisite stockholder approval to complete the proposed transaction, the risk that the combined company may not obtain approval to list the shares of common stock of the combined company on the NASDAQ Stock Market after the assumed closing of the merger and risks and other uncertainties more fully described in DPI's registration statement on Form S-4, as amended, as filed with the Securities and Exchange Commission and DPI's other SEC reports. You are urged to consider statements that include the words "may," "will," "would," "could," "should," "believes," "estimates," "projects," "potential," "expects," "plans," "anticipates," "intends," "continues," "forecast," "designed," "goal," or the negative of those words or other comparable words to be uncertain and forward-looking. The transaction is subject to customary closing conditions, including approval of DPI's and Infinity's stockholders. Any forward-looking statements contained in this press release speak only as of the date hereof and Infinity expressly disclaims any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise. Editor's Note: This release is available in the Press Release section of the Media Room of Infinity's website at http://www.ipi.com/. Contacts: Investors: John Evans Media: Monique Allaire 617.453.1254 617.453.1105 DATASOURCE: Infinity Pharmaceuticals, Inc. CONTACT: John Evans (Investors), +1-617-453-1254, , or Monique Allaire (Media), +1-617-453-1105, , both of Infinity Pharmaceuticals, Inc. Web site: http://www.ipi.com/ http://www.discoverypartners.com/ http://www.sec.gov/

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