UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 10-Q/A

Amendment No. 1

[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
ACT OF 1934

For the quarterly period ended June 30, 2014

[ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934

For the transition period from ___________ to ___________

Commission File No. 000-54626

SIGNAL ADVANCE, INC.
(Exact name of registrant as specified in its charter)

Texas
(State or Other Jurisdiction of Incorporation or Organization)

8731
(Primary Standard Industrial Classification Number)

76-0373052
(IRS Employer Identification Number)

2520 County Road 81
Rosharon, Texas 77583
(713) 510-7445
(Address and telephone number of principal executive offices)

Securities registered pursuant to Section 12(b) of the Act: None

Securities registered pursuant to Section 12(g) of the Act: None

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Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for shorter period that the registrant as required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes [X] No [ ]

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (Sec. 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes [X] No [ ]

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, or a non-accelerated filer. See definition of "accelerated filer and large accelerated filer" in Rule 12b-2 of the Exchange Act.(Check one)

Large accelerated filer [ ] Accelerated filer [ ] Non-accelerated filer [ ] Smaller reporting company [X]

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act). Yes [ ] No [X]

As of August 14, 2014, the registrant had 9,925,409 shares of common stock issued and outstanding. No market value has been computed based upon the fact that no active trading market has been established as of August 14, 2014.

EXPLANATORY NOTE

Signal Advance, Inc. is filing this Amendment No. 1 (on Form 10-Q/A) to its Quarterly Report on Form 10-Q for the six months ended June 30, 2014, originally filed with the Commission on August 14, 2014. This Form 10-Q/A is being filed solely for the purpose of a typograpical error, specifically the period and date indicated in Exhibit 32.1. There are no amendments to the additional exhibits, the original Form 10-Q or the interactive (XBRL) data.

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SIGNATURES

In accordance with the requirements of the Exchange Act, the registrant caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Dated: August 21, 2014                  SIGNAL ADVANCE, INC.
                                        By: /s/ Chris M. Hymel
                                        Chris M. Hymel, President/Treasurer

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and as of the dates indicated.

SIGNATURE                 TITLE                               DATE
-----------------------   -------------------------------     ---------------

/s/ Chris M. Hymel        Member, Board of Directors,         August 21, 2014
Chris M. Hymel            President and Treasurer
                          (Principal Executive, Financial
                           and Accounting Officer)


/s/ Malcolm H. Skolnick   Member: Board of Directors,         August, 21 2014
Malcolm H. Skolnick       Secretary


/s/ Richard C. Seltzer    Member of the Board of Directors    August 21, 2014
Richard C. Seltzer

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