Atreca Reports Third Quarter 2021 Financial Results and Recent Corporate Developments
02 11월 2021 - 9:30PM
Atreca, Inc. (Atreca) (NASDAQ: BCEL), a clinical-stage
biotechnology company focused on developing novel therapeutics
generated through a unique discovery platform based on
interrogation of the active human immune response, today announced
financial results for the third quarter ended September 30, 2021,
and provided an overview of recent developments.
"In the third quarter, we continued to advance our lead program,
ATRC-101, following the release of initial summary data from the
dose escalation portion of the Phase 1b trial, which supports the
further evaluation of ATRC-101 in multiple solid tumor types,” said
John Orwin, Chief Executive Officer. “We plan to share additional
monotherapy data and initial combination data with pembrolizumab in
2022, and are in a strong position to advance our pipeline with
cash runway through mid-2023.”
“Our earlier-stage programs are progressing well, highlighted by
our recently announced licensing agreement with the Bill &
Melinda Gates Medical Research Institute for the development and
commercialization of MAM01/ATRC-501, a novel monoclonal antibody
entering preclinical development for the prevention of malaria,”
said Tito Serafini, Ph.D., Chief Strategy Officer. “We look forward
to sharing more information on our EphA2 program and other pipeline
assets at an R&D day early next year.”
Recent Developments and Highlights
- Atreca announced a licensing
agreement with the Bill & Melinda Gates Medical Research
Institute (“Gates MRI”) for development and commercialization of
MAM01/ATRC-501, a monoclonal antibody for malaria prophylaxis.
Under the agreement, Gates MRI will lead the development of
MAM01/ATRC-501 and receive commercial rights in GAVI-eligible
countries located in malaria-endemic regions of the world, while
Atreca will retain commercial rights in the U.S., Europe and parts
of Asia. Potential product development opportunities for Atreca
include developing MAM01/ATRC-501 for prevention of malaria for
those traveling to regions where the infection may be
circulating.
- Enrollment in the monotherapy
portion of the Phase 1b trial of ATRC-101 is ongoing at 30 mg/kg
and Atreca plans to report additional monotherapy data in
mid-2022.
- Enrollment has commenced in a Phase
1b combination cohort evaluating ATRC-101 with pembrolizumab.
Another combination cohort with pegylated liposomal doxorubicin
(“PLD”) is expected to begin enrolling patients following
completion of ongoing monotherapy cohorts, including those
following a Q2W dosing schedule which better aligns with the
standard PLD regimen. Atreca plans to report additional monotherapy
data in mid-2022 and pembrolizumab combination data in 3Q22.
Third Quarter 2021 Financial Results
- As of September 30, 2021, cash and cash equivalents and
short-term investments totaled $152.9 million.
- Research and development expenses for the three months ended
September 30, 2021 were $18.7 million, including non-cash
share-based compensation expense of $1.9 million.
- General and administrative expenses for the three months ended
September 30, 2021 were $8.8 million, including non-cash
share-based compensation expense of $1.9 million.
- Atreca reported a net loss of $27.4 million, or basic and
diluted net loss per share attributable to common stockholders of
$0.74, for the three months ended September 30, 2021.
About Atreca, Inc.
Atreca is a biopharmaceutical company developing novel
antibody-based immunotherapeutics generated by its differentiated
discovery platform. Atreca's platform allows access to an
unexplored landscape in oncology through the identification of
unique antibody-target pairs generated by the human immune system
during an active immune response against tumors. These antibodies
provide the basis for first-in-class therapeutic candidates, such
as our lead product candidate ATRC-101. A Phase 1b study evaluating
ATRC-101 in multiple solid tumor cancers is currently enrolling
patients. For more information on Atreca, please visit
www.atreca.com.
Forward-Looking Statements
Statements contained in this press release regarding matters
that are not historical facts are “forward-looking statements”
within the meaning of the Private Securities Litigation Reform Act
of 1995. These forward-looking statements include, but are not
limited to, statements about our plans, objectives, representations
and contentions and typically are identified by use of terms such
as “will,” “expect,” “potential,” “plan,” “continue,” and similar
words, although some forward-looking statements are expressed
differently. These statements include those related to our strategy
and future plans, including statements regarding the development of
ATRC-101 and our preclinical, clinical and regulatory plans and the
timing thereof, the availability and timing of ATRC-101 monotherapy
and initial combination data with pembrolizumab and enrollment in,
and timing of, a combination cohort with pegylated liposomal
doxorubicin, our cash runway and the timing thereof, the
development of MAM01/ATRC-501, its potential for prevention of
malaria, our potential product development opportunities to develop
MAM01/ATRC-501 for prevention of malaria for those traveling to
regions where the infection may be circulating, and the status of
our earlier-stage programs and our plan to share information
regarding our EphA2 program and other pipeline assets and the
timing thereof. Our actual results may differ materially from those
indicated in these forward-looking statements due to risks and
uncertainties related to the initiation, timing, progress and
results of our research and development programs, preclinical
studies, clinical trials, regulatory submissions, and other matters
that are described in our filings with the Securities and Exchange
Commission (SEC) and available on the SEC’s website
at www.sec.gov, including in the “Risk Factors” and
“Management’s Discussion and Analysis of Financial Condition and
Results of Operations” sections of our most recently filed annual
report on Form 10-K and quarterly report on Form 10-Q. Investors
are cautioned not to place undue reliance on these forward-looking
statements, which speak only as of the date of this press release,
and we undertake no obligation to update any forward-looking
statement in this press release, except as required by law.
Atreca, Inc.Condensed
Consolidated Balance Sheets(in thousands, except share and
per share data)
|
|
|
|
|
|
|
September 30, |
|
December 31, |
|
|
|
2021 |
|
|
|
2020 |
|
|
|
(unaudited) |
|
|
ASSETS |
|
|
|
|
|
|
|
|
|
Current Assets |
Cash and cash equivalents |
|
$ |
113,189 |
|
|
$ |
60,789 |
|
Investments |
|
|
39,697 |
|
|
|
179,296 |
|
Prepaid expenses and other
current assets |
|
|
9,180 |
|
|
|
9,037 |
|
Total current assets |
|
|
162,066 |
|
|
|
249,122 |
|
Property and equipment,
net |
|
|
44,291 |
|
|
|
19,831 |
|
Long-term investments |
|
|
10,824 |
|
|
|
- |
|
Deposits and other |
|
|
3,080 |
|
|
|
3,111 |
|
Total assets |
|
$ |
220,261 |
|
|
$ |
272,064 |
|
|
|
|
|
|
LIABILITIES AND STOCKHOLDERS’ EQUITY |
|
|
|
|
|
Current Liabilities |
Accounts payable |
|
$ |
5,238 |
|
|
$ |
5,216 |
|
Accrued expenses |
|
|
9,286 |
|
|
|
10,302 |
|
Other current liabilities |
|
|
1,631 |
|
|
|
1,900 |
|
Total current liabilities |
|
|
16,155 |
|
|
|
17,418 |
|
Capital lease obligations, net
of current portion |
|
|
- |
|
|
|
4 |
|
Deferred rent |
|
|
28,677 |
|
|
|
12,585 |
|
Total liabilities |
|
|
44,832 |
|
|
|
30,007 |
|
|
|
|
|
|
|
|
|
|
|
Stockholders’ equity |
Common stock |
|
|
4 |
|
|
|
4 |
|
Additional paid-in
capital |
|
|
505,680 |
|
|
|
492,436 |
|
Accumulated other
comprehensive income (loss) |
|
|
(6 |
) |
|
|
58 |
|
Accumulated deficit |
|
|
(330,249 |
) |
|
|
(250,441 |
) |
Total stockholders’ equity |
|
|
175,429 |
|
|
|
242,057 |
|
Total liabilities and stockholders’ equity |
|
$ |
220,261 |
|
|
$ |
272,064 |
|
Atreca, Inc.Condensed
Consolidated Statements of Operations(in thousands, except
share and per share data)(unaudited)
($ amounts in
000's, except per share amounts) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
Nine Months Ended |
|
|
|
September 30, |
|
September 30, |
|
|
|
|
2021 |
|
|
|
2020 |
|
|
|
2021 |
|
|
|
2020 |
|
|
|
|
|
|
|
|
|
|
|
Expenses |
|
|
|
|
|
|
|
|
|
Research and development |
|
$ |
18,721 |
|
|
$ |
16,808 |
|
|
$ |
56,145 |
|
|
$ |
45,198 |
|
|
General and
administrative |
|
|
8,796 |
|
|
|
6,614 |
|
|
|
24,648 |
|
|
|
20,195 |
|
|
Total expenses |
|
|
27,517 |
|
|
|
23,422 |
|
|
|
80,793 |
|
|
|
65,393 |
|
Interest and other
income (expense) |
|
|
|
|
|
|
|
|
|
Other income |
|
|
158 |
|
|
|
353 |
|
|
|
851 |
|
|
|
987 |
|
|
Interest income |
|
|
36 |
|
|
|
142 |
|
|
|
183 |
|
|
|
1,082 |
|
|
Interest expense |
|
|
(1 |
) |
|
|
(1 |
) |
|
|
(3 |
) |
|
|
(3 |
) |
|
Loss on disposal of property
and equipment |
|
|
(34 |
) |
|
|
- |
|
|
|
(45 |
) |
|
|
- |
|
Loss before Income
tax expense |
|
|
(27,358 |
) |
|
|
(22,928 |
) |
|
|
(79,807 |
) |
|
|
(63,327 |
) |
Income tax
expense |
|
|
- |
|
|
|
(1 |
) |
|
|
(1 |
) |
|
|
(1 |
) |
Net loss |
|
$ |
(27,358 |
) |
|
$ |
(22,929 |
) |
|
$ |
(79,808 |
) |
|
$ |
(63,328 |
) |
Net loss per
share, basic and diluted |
|
$ |
(0.74 |
) |
|
$ |
(0.66 |
) |
|
$ |
(2.16 |
) |
|
$ |
(2.09 |
) |
Weighted-average
shares used in computing |
|
|
|
|
|
|
|
|
net loss per share, basic and diluted |
|
|
36,918,255 |
|
|
|
34,723,888 |
|
|
|
36,884,665 |
|
|
|
30,313,047 |
|
Contacts
Atreca, Inc.Herb CrossChief Financial
Officerinfo@atreca.comInvestors:Alex Gray,
650-779-9251agray@atreca.com
Media:Rachel Ford Hutman,
301-801-5540Rachel@fordhutmanmedia.com
Source: Atreca, Inc.
Atreca (NASDAQ:BCEL)
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