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Lipella Pharmaceuticals Inc

Lipella Pharmaceuticals Inc (LIPO)

3.52
-0.08
( -2.22% )
업데이트: 23:44:53
고급 차트

실시간 스트리밍 인용문, 아이디어 및 실시간 토론을 위한 허브

주요 통계 및 세부정보

가격
3.52
매수가
3.52
매도가
3.54
거래량
14,165
3.52 일간 변동폭 3.555
2.21 52주 범위 12.00
market_cap
전일 종가
3.60
개장가
3.53
최근 거래 시간
200
@
3.52
마지막 거래 시간
23:44:53
재정 규모
US$ 49,931
VWAP
3.525
평균 볼륨(3m)
2,571,717
발행 주식
1,208,919
배당수익률
-
주가수익률
-0.94
주당순이익(EPS)
-3.82
매출
450k
순이익
-4.62M

Lipella Pharmaceuticals Inc 정보

Lipella Pharmaceuticals Inc., a clinical-stage biotechnology company, focuses on developing drugs by reformulating the active agents in existing generic drugs and optimizing these reformulations for various applications. It is developing LP-10, a formulation of tacrolimus that is in Phase IIa clinic... Lipella Pharmaceuticals Inc., a clinical-stage biotechnology company, focuses on developing drugs by reformulating the active agents in existing generic drugs and optimizing these reformulations for various applications. It is developing LP-10, a formulation of tacrolimus that is in Phase IIa clinical trial for patients with radiation-induced hemorrhagic cystitis; and LP-310, a formulation of tacrolimus for the treatment of oral lichen planus. Lipella Pharmaceuticals Inc. was incorporated in 2005 and is based in Pittsburgh, Pennsylvania. 더 보기

섹터
Pharmaceutical Preparations
산업
Pharmaceutical Preparations
웹사이트
본부
Wilmington, Delaware, USA
설립됨
-
Lipella Pharmaceuticals Inc is listed in the Pharmaceutical Preparations sector of the 나스닥 with ticker LIPO. The last closing price for Lipella Pharmaceuticals was US$3.60. Over the last year, Lipella Pharmaceuticals shares have traded in a share price range of US$ 2.21 to US$ 12.00.

Lipella Pharmaceuticals currently has 1,208,919 shares in issue. The market capitalisation of Lipella Pharmaceuticals is US$4.35 million. Lipella Pharmaceuticals has a price to earnings ratio (PE ratio) of -0.94.

LIPO 최신 뉴스

기간변동변동 %시가고가저가평균 일일 거래량VWAP
1-0.55-13.51351351354.074.53.55227744.21993049CS
40.6522.64808362372.877.312.573208414.50774779CS
120.7225.71428571432.87.312.525717174.45918165CS
260.1925.769230769233.3287.312.2116880024.1137718CS
52-4.48-568122.2116919525.62146952CS
156-52.64-93.732193732256.1661.762.219899358.7654027CS
260-52.64-93.732193732256.1661.762.219899358.7654027CS

LIPO - Frequently Asked Questions (FAQ)

What is the current Lipella Pharmaceuticals share price?
The current share price of Lipella Pharmaceuticals is US$ 3.52
How many Lipella Pharmaceuticals shares are in issue?
Lipella Pharmaceuticals has 1,208,919 shares in issue
What is the market cap of Lipella Pharmaceuticals?
The market capitalisation of Lipella Pharmaceuticals is USD 4.35M
What is the 1 year trading range for Lipella Pharmaceuticals share price?
Lipella Pharmaceuticals has traded in the range of US$ 2.21 to US$ 12.00 during the past year
What is the PE ratio of Lipella Pharmaceuticals?
The price to earnings ratio of Lipella Pharmaceuticals is -0.94
What is the cash to sales ratio of Lipella Pharmaceuticals?
The cash to sales ratio of Lipella Pharmaceuticals is 9.67
What is the reporting currency for Lipella Pharmaceuticals?
Lipella Pharmaceuticals reports financial results in USD
What is the latest annual turnover for Lipella Pharmaceuticals?
The latest annual turnover of Lipella Pharmaceuticals is USD 450k
What is the latest annual profit for Lipella Pharmaceuticals?
The latest annual profit of Lipella Pharmaceuticals is USD -4.62M
What is the registered address of Lipella Pharmaceuticals?
The registered address for Lipella Pharmaceuticals is 108 WEST 13TH STREET, WILMINGTON, DELAWARE, 19801
What is the Lipella Pharmaceuticals website address?
The website address for Lipella Pharmaceuticals is www.lipella.com
Which industry sector does Lipella Pharmaceuticals operate in?
Lipella Pharmaceuticals operates in the PHARMACEUTICAL PREPARATIONS sector

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LIPO 금융

금융
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LIPO Discussion

게시물 보기
subslover subslover 1 주 전
Lipella Pharmaceuticals Reports Positive Topline Phase 2a Results for LP-310 in the Treatment of Oral Lichen Planus
February 11 2025 - 5:46AM

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Lipella Pharmaceuticals Inc. (Nasdaq: LIPO) (“Lipella,” “our,” “us,” or the “Company”), a clinical-stage biotechnology company addressing serious diseases with significant unmet needs, today shared topline analysis of its Phase 2a multicenter dose-ranging trial examining LP-310, a liposomal-tacrolimus oral rinse formulation of LP-10 being developed to treat oral lichen planus (“OLP”).
LP-310 demonstrated a strong safety profile, with no product-related serious adverse events (SAEs) and no patient dropouts. The trial showed statistically significant improvements across multiple patient-reported and investigator-measured efficacy endpoints at weeks 1, 4, and 6. LP-310 is the only oral rinse topical treatment currently in development for OLP.

Lipella Pharmaceuticals’ management will provide an overview of the Company and present results from the study during the BIO CEO & Investor Conference at The New York Marriott Marquis in New York City on Tuesday, Feb. 11, 2025, at 2:30 p.m. EST in the Plymouth Room.

Affecting about 6 million Americans, OLP is a chronic inflammatory condition that targets mucous membranes in the mouth, which can cause pain and make eating, drinking and even speaking uncomfortable. Characterized by symptoms such as burning pain, white patches, swollen tissue and open sores, OLP has no FDA-approved therapies.

“OLP represents a significant unmet need, and these remarkable results are highly encouraging, underscoring the meaningful value LP-310 can bring to both patients and the broader healthcare system,” added Jonathan Kaufman, Co-Founder and CEO of Lipella Pharmaceuticals. “With a chronic condition like OLP, delivering a targeted, effective treatment that overcomes the challenges of current options is vital. We are thrilled to advance its development and unlock its full potential.”

In the study’s first cohort, eight participants received a twice-daily dose of 0.25 mg of LP-310. Follow-up visits occurred at one and four weeks as well as two weeks post-treatment. The trial showed significant improvements across multiple efficacy endpoints while suggesting the safety and tolerability of LP-10 in adult patients with symptomatic OLP at the 0.25 mg/10 mL dose. The trial, which is active across seven U.S. sites, has progressed to the next higher dose cohort of 0.5 mg/10 mL.

Topline Findings:

Investigator Global Assessment (IGA): Improved from 3.50 ± 0.19 at baseline to 2.75 ± 0.31 at week 1 (p=0.031), 1.75 ± 0.45 at week 4 (p=0.008), and 2.80 ± 0.37 at week 6 (p=0.125).
Reticulation, Erythema, and Ulceration (REU) Score: Reduced from 27.75 ± 2.71 at baseline to 17.56 ± 2.51 at week 1 (p=0.004), 12.69 ± 3.06 at week 4 (p=0.004), and 19.60 ± 4.31 at week 6 (p=0.031).
Oral Lichen Planus Symptom Severity Measure (OLPSSM): Decreased from 15.38 ± 2.20 at baseline to 10.13 ± 2.34 at week 1 (p=0.035), 5.00 ± 2.28 at week 4 (p=0.004), and 8.60 ± 4.06 at week 6 (p=0.031).
Pain Numerical Rating Scale (NRS): Improved from 6.63 ± 0.80 at baseline to 4.38 ± 0.96 at week 1 (p=0.004), 2.38 ± 1.15 at week 4 (p=0.004), and 3.60 ± 1.63 at week 6 (p=0.031).
Global Response Assessment (GRA): Significant improvement was observed at week 4 (p=0.031).
“The statistically significant reductions in pain, ulceration, and inflammation observed in this trial provide strong grounds for the scientific validation of LP-310’s efficacy,” said Dr. Michael Chancellor, Co-Founder and Chief Medical Officer of Lipella Pharmaceuticals. “These results, combined with the treatment’s favorable safety profile, highlight the potential of LP-310 to deliver a highly targeted and tolerable therapy for OLP. We are deeply grateful to the patients and investigators for their contributions to this critical study and inspired by the marked improvements we’ve seen in patients’ lives. We look forward to advancing the trial to the next dose cohort and expanding recruitment across seven active U.S. sites as we continue to build on these promising findings.”

Safety and Tolerability
LP-310 was well tolerated with no product-related serious adverse events reported. All patients adhered to the twice-daily 10 mL rinse regimen, with no dropouts during the study. Pharmacokinetic analysis showed that tacrolimus blood levels were undetectable or minimal in all patients, underscoring LP-310’s potential to deliver localized benefits without systemic toxicity.

Next Steps in Development
Lipella continues to recruit for the trial, with plans to activate additional sites and complete the trial by mid-2025. The company is preparing for key milestones, including the submission of a Phase 2b clinical trial investigational new drug application in the second half of 2025 and a Breakthrough Therapy designation request to the FDA during the same period.

About LP-310
LP-310 is an innovative oral rinse formulation of LP-10 (tacrolimus), developed to address OLP. Designed to provide localized therapeutic effects while minimizing systemic exposure, LP-310 offers a promising new approach to managing this painful and often debilitating condition.

A Phase 2a multicenter, dose-ranging clinical trial is currently underway to evaluate the safety, tolerability and efficacy of LP-310 in adult participants with symptomatic OLP. The trial includes three dose levels (0.25 mg, 0.5 mg, and 1.0 mg of tacrolimus) and is being conducted across seven active U.S. sites, which are now recruiting participants. The study has reported topline data from its first cohort, with the second cohort currently dosing and topline data expected in the first half of 2025.

For more information about the study or to participate, visit https://lipella.com/oral-lichen-planus-treatment/ or https://clinicaltrials.gov/study/NCT06233591.

About Lipella Pharmaceuticals Inc.
Lipella Pharmaceuticals is a clinical-stage biotechnology company focused on developing new drugs by reformulating active agents in existing generic drugs and optimizing these reformulations for new applications. Lipella targets diseases with significant unmet needs, where no approved drug therapies currently exist. The company completed its initial public offering in 2022. Learn more at lipella.com and follow us on X and LinkedIn.
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tw0122 tw0122 1 주 전
Suction power reactivates for a limited time only special.)3.05 to 5.08 +'65% has to break $5.44 to test $6s again
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Invest-in-America Invest-in-America 2 주 전
LIPO: Meant to say, NOW getting .........
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Invest-in-America Invest-in-America 2 주 전
LIPO: Non getting powerful 'LIPO-suction' upon its (formerly) soaring PRICE. (No pun intended.)
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subslover subslover 2 주 전
😁CONGRATS!😷
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tw0122 tw0122 2 주 전
$7s cash most out ....$$$ 7.13
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subslover subslover 2 주 전
She is on fire!😍
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TrendTrade2016 TrendTrade2016 2 주 전
ALGOS USING THE LETTERS FDA TO TRUST THE ROBOTS ....ITS NOT A FDA APPROVAL....SO THEY DILUTE TO FUND THE TRIALS
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TrendTrade2016 TrendTrade2016 2 주 전
DILUTION HITTING
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TrendTrade2016 TrendTrade2016 2 주 전
GAPPO TRAPPO
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Invest-in-America Invest-in-America 2 주 전
LIPO: Float so tiny, put it in your back pocket.
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tw0122 tw0122 2 주 전
Nice news been running nicely $5.90 +'128%
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subslover subslover 2 주 전
Lipella Pharmaceuticals Granted FDA Approval for Expanded Access Program for LP-310 in Oral Lichen Planus
PITTSBURGH, Feb. 06, 2025 (GLOBE NEWSWIRE) -- Lipella Pharmaceuticals Inc. (Nasdaq: LIPO) (“Lipella” or the “Company”), a clinical-stage biotechnology company focused on developing innovative therapies for unmet medical needs, today announced that the U.S. Food and Drug Administration (FDA) has granted approval for an Expanded Access Program (EAP) for LP-310, an oral rinse formulation designed to treat oral lichen planus (OLP).

LP-310 is an innovative, localized therapy formulated to provide targeted relief for OLP patients while minimizing systemic exposure. Oral lichen planus is a chronic inflammatory condition affecting the mucous membranes inside the mouth, often causing burning pain, white patches, swollen tissue and open sores. The condition impacts approximately 6 million Americans and currently has no FDA-approved therapies.

Expanded Access Programs allow patients who have unmet medical needs with serious or life-threatening conditions to access treatments outside of a clinical trial that are not yet approved by the FDA.

“Receiving FDA approval for expanded use of LP-310 represents a key milestone in our mission to address the significant unmet need in oral lichen planus treatment,” said Michael Chancellor, Co-Founder and Chief Medical Officer of Lipella Pharmaceuticals. “We are pleased to make LP-310 available to patients beyond our Phase 2a clinical trial through this expanded access program. With no approved therapies currently available, this approval strengthens our commitment to advancing LP-310 as a potential solution for patients living with this painful and often debilitating condition.”

The FDA’s approval for expanded use reinforces LP-310’s potential as a new therapeutic option for OLP and supports ongoing clinical development efforts.

About LP-310
LP-310 is an oral rinse formulation of LP-10 (tacrolimus) developed to target inflammation and immune response in OLP patients. Designed for localized therapeutic effects, LP-310 minimizes systemic exposure, reducing the risks associated with long-term steroid use. A Phase 2a multicenter, dose-ranging clinical trial is currently underway to evaluate the safety, tolerability and efficacy of LP-310 in adult participants with symptomatic OLP. The trial includes three dose levels (0.25 mg, 0.5 mg and 1.0 mg of tacrolimus) and is being conducted across seven active U.S. sites, which are now recruiting participants.
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tw0122 tw0122 3 월 전
Zzzz $3 smaller float + 8%!
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IronMaverick63 IronMaverick63 3 월 전
Lipo should be 10 usd before 2025
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TheFinalCD TheFinalCD 4 월 전
thanks but I was sleeping....


zzzzzzz
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tw0122 tw0122 4 월 전
.57 + 41%
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tw0122 tw0122 4 월 전
.53+ 33% Lipella Pharmaceuticals Announces U.S. Patent Allowance for Innovative Liposomal Drug Delivery Platform

Source: GlobeNewswire Inc.

Lipella Pharmaceuticals Inc. (Nasdaq: LIPO), a clinical-stage biotechnology company focused on developing therapies for serious diseases with unmet medical needs, today announced the receipt of a notice of allowance from the U.S. Patent and Trademark Office (USPTO) for its proprietary liposomal drug delivery platform. The patent application, U.S. Patent No. 17/829,960, titled "Delivery of Agents Using Metastable Liposomes," covers key innovations in Lipella’s platform technology for delivering therapeutic agents via liposome-based vehicles.
The patent allows claims that cover Lipella’s method for using metastable liposomes to deliver a variety of therapeutic agents, including the company’s lead assets, LP-10 and LP-310. This breakthrough technology enables precise, targeted delivery, improving the safety and efficacy of treatments across multiple therapeutic areas, including oncology, cancer survivorship, and immunotherapy.

Dr. Michael Chancellor, Chief Medical Officer of Lipella Pharmaceuticals, commented, "The allowance of this patent is a significant milestone for Lipella as it strengthens our intellectual property portfolio and supports our ongoing efforts to advance therapies for conditions such as hemorrhagic cystitis and oral lichen planus. Our liposomal drug delivery system offers a safer and more effective means of administering therapeutics like tacrolimus by targeting disease sites directly and minimizing the systemic side effects typically associated with these treatments."

This newly allowed patent provides broad intellectual property protection for Lipella’s drug delivery platform, which optimizes delivery to epithelial tissues such as those lining the mouth, bladder, colon, esophagus, vagina, and urethra. It extends market exclusivity and strengthens Lipella’s competitive position, particularly for its two lead clinical assets currently in Phase 2 trials. With additional patents covering the company's formulations in the U.S., Australia, and Canada until 2035, Lipella is poised for further growth and development as it continues to advance its clinical pipeline.

About Lipella’s Lead Clinical Assets: LP-10 and LP-310

LP-10 is a liposomal formulation of tacrolimus designed for intravesical administration to treat hemorrhagic cystitis (HC), a rare but severe condition characterized by bleeding from the bladder. LP-10 has shown promising safety and efficacy results in a multicenter Phase 2a trial, where it improved urinary symptoms in patients. The FDA has granted Orphan Drug Designation to LP-10 for the treatment of moderate to severe HC, further underscoring its potential to address this critical unmet need. A Phase 2b multicenter placebo-controlled trial is ready to begin.
LP-310 is an innovative oral rinse formulation of LP-10, designed to treat oral lichen planus (OLP), a chronic autoimmune disease affecting the mucous membranes of the mouth. LP-310 offers a promising new approach to treating OLP, which affects millions of Americans and currently lacks an approved pharmacotherapy. A Phase 2a multicenter trial is underway with anticipated top-line data by year-end and trial completion by mid-2025.
About Hemorrhagic Cystitis (HC)
Hemorrhagic cystitis is a serious condition often resulting from radiation therapy or chemotherapy, marked by severe bleeding in the bladder. With no FDA-approved drug treatments available, LP-10 is positioned to become a breakthrough therapy for patients suffering from this debilitating condition.

About Oral Lichen Planus (OLP)
Oral lichen planus is a chronic autoimmune disease that causes inflammation and lesions in the oral mucosa. It can lead to significant discomfort, scarring, and increased risk of oral cancer. Despite affecting six to seven million people in the U.S., there are no approved treatments, and current therapies offer only symptomatic relief.

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tw0122 tw0122 4 월 전
Hop on board pump time .52 +’32%
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glenn1919 glenn1919 5 월 전
LIPO............................https://stockcharts.com/h-sc/ui?s=LIPO&p=W&b=5&g=0&id=p86431144783
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TheFinalCD TheFinalCD 5 월 전
https://x.com/prism_mediawire/status/1838551573447754079
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tw0122 tw0122 5 월 전
Give me some liposuction and pump me up
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Monksdream Monksdream 6 월 전
LIPO new 52 low
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Monksdream Monksdream 6 월 전
LIPO new 52
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TheFinalCD TheFinalCD 7 월 전
agree but the market doesnt *NHOD*
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Swammmie1040 Swammmie1040 7 월 전
lol bounced out garbage geeezzzz
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Swammmie1040 Swammmie1040 7 월 전
Churning good bounce coming
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PirateLeviathan8 PirateLeviathan8 7 월 전
only initiates Phase 2a Trial
where is the big news ?

is just to collect money
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harry crumb harry crumb 7 월 전
Halted!, in at average .90, easily a 3$ stock here $$$$$$
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MartinLutherKing MartinLutherKing 7 월 전
God Bless LIPO God Bless RNAZ
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Awl416 Awl416 7 월 전
Ahhhhh chew. Bless me
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Awl416 Awl416 7 월 전
Don’t blink
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Awl416 Awl416 7 월 전
Golf clap
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glenn1919 glenn1919 7 월 전
LIPO...............................https://stockcharts.com/h-sc/ui?s=LIPO&p=W&b=5&g=0&id=p86431144783
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TheFinalCD TheFinalCD 7 월 전
LIPO NEWS https://www.globenewswire.com/news-release/2024/07/29/2920081/0/en/Lipella-Pharmaceuticals-Initiates-Phase-2a-Trial-for-LP-310-in-Oral-Lichen-Planus-Enrolls-First-Patients.html
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tw0122 tw0122 7 월 전
LIPO .80s now cash out time
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FALCON1 FALCON1 7 월 전
https://www.zacks.com/stock/news/2300964/the-zacks-analyst-blog-highlights-danaher-morgan-stanley-pfizer-elite-pharmaceuticals-and-oil-dri

https://www.zacks.com/stock/news/2300922/zacks-initiates-coverage-of-elite-pharmaceuticals-with-outperform-recommendation
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oldstocks oldstocks 12 월 전
You made me feel old, then i remembered my grandchildren
541,000 LIPO shares traded down 1.9%
Wow normally low volume
J A G X had a lot of volume too 380 mill
Pharmaceuticals are hot
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Muhbruh Muhbruh 12 월 전
https://twitter.com/StocksGambino/status/1764482368113410078
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Monksdream Monksdream 12 월 전
Roll the dice, gramps you can’t take it with you
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oldstocks oldstocks 12 월 전
This doesn’t trade many shares.
Volume is coming
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Monksdream Monksdream 12 월 전
LIPO under $2
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crudeoil24 crudeoil24 1 년 전
Heading to FDA phase II trial. Long ways to go before FDA phase III approval for marketplace.
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crudeoil24 crudeoil24 1 년 전
Shares of Lipella Pharmaceuticals Inc. (LIPO) rocketed 52.2% higher in very active tracing Friday, after the Pittsburgh-based biotechnology company's investigational new drug application for its oral lichen planus treatment was approved by the U.S. Food and Drug Administration. Trading volume in the stock, which was the best performer on the major U.S. exchanges, blasted higher to 30.7 million shares, compared with the full-day average of about 6,400 shares. The stock has soared 150% in the three days since it last closed below the $1 mark, and has run up 164% amid a six-day winning streak. as Lipella described, OLP is a chronic, inflammatory autoimmune oral muscosal disease. It is a "highly morbid" condition with malignant potential that affects between 1% and 4% of the world population. Lipella's stock has now gained 18.6% over the past three months, but was still 57% below its initial public offering price of $5.75; the company went public on Dec. 20.

-Tomi Kilgore

For more from MarketWatch: http://www.marketwatch.com/newsviewer
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Monksdream Monksdream 1 년 전
Early Barchart Top 100
https://www.barchart.com/stocks/performance/percent-change/advances?orderBy=percentChange&orderDir=desc
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Awl416 Awl416 1 년 전
Lipella Pharmaceuticals Announces FDA Clearance of IND for LP-310 for Oral Lichen Planus
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MiamiGent MiamiGent 2 년 전
That's it for me, folks!
Went much longer than usual but I have had a terrific day-following a bad day yesterday.
Hit on LIPO news today. Was positioned for the good pop. What a difference a day can make!
Have to drive across the mountain, now. Go do inventory at a shop open late. Then deliver there tomorrow.

LIPO Quote
AS OF 3/16/2023 3:16PM ET

$2.54
+$0.71 (+38.798%)

Volume
22,990,230
90 Day Avg. Vol.
564,085
Open
$2.77
Previous Close 03/15/2023
$1.83

https://stockcharts.com/h-sc/ui?s=LIPO
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TheFinalCD TheFinalCD 2 년 전
LIPO NEWS https://finance.yahoo.com/news/lipella-pharmaceuticals-successfully-completes-phase-123000776.html


Hemorrhagic cystitis is a medical condition that occurs when your urinary bladder lining becomes inflamed and bleeds. Your bladder is a muscular sac in your pelvis that stores urine before it's released from your body. Hemorrhagic means bleeding, and cystitis is inflammation of the bladder
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81vette 81vette 2 년 전
Lipella Pharmaceuticals’ (NASDAQ:LIPO – Get Rating) quiet period will expire on Monday, January 30th. Lipella Pharmaceuticals had issued 1,217,391 shares in its IPO on December 20th. The total size of the offering was $6,999,998 based on an initial share price of $5.75. During Lipella Pharmaceuticals’ quiet period, insiders and underwriters involved in the IPO are prevented from issuing any research reports or earnings estimates for the company because of regulations issued by the Securities and Exchange Commission. Following the end of the company’s quiet period, it’s expected that the brokerages that served as underwriters on the stock will initiate research coverage on the company.
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81vette 81vette 2 년 전
65,502 failure to deliver from 1-13 ,wow $300,000@$3.00pps ,insane margin call,shorts better cover now,at ask would put LIPO over $100pps right now ,set my sell at $150.00 just in case
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