RNS No 182e
OXFORD INSTRUMENTS PLC
21 April 1999


The Company has been notified today for the purposes of S.198 Companies Act
1985: as amended by the Disclosure of Interest in Shares (Amendment)
Regulations 1993 (ORD 5p) that Phillips & Drew Life Limited has a notifiable
interest in 2,325,250 Ordinary Shares of 5p each which, represents 4.86% of
the issued share capital of Oxford Instruments plc.

The shares to which this notification relates are registered as follows:

Registered Holder                           Number of Shares
Phildrew Nominees Limited a/c LF06               13,740
Phildrew Nominees Limited a/c LF20            2,311,510
                                              ----------
TOTAL                                         2,325,250

Phillips & Drew Life Limited is a subsidiary of Phillips & Drew Holding
Limited which is also treated as having an interest in the above shares.



Della Gorham (Mrs)
Assistant Company Secretary



END

HOLBUGBSUUDCCCB


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