Targeted Genetics to Host Conference Call and Webcast Discussion of Fourth Quarter and 2007 Results on March 25, 2008

SEATTLE, WA will report its fourth quarter and full-year 2007 financial results before the open of the financial markets on Tuesday, March 25, 2008. Following the announcement, management will host a conference call and webcast discussion of the financial results and provide a general corporate update beginning at 10:30 a.m. Eastern Time / 7:30 a.m. Pacific Time. You may access the live webcast via the "Events" section found on the homepage of the Company's website at www.targetedgenetics.com or via telephone at 800.240.4186 (domestic) or 303.262.2139 (international).

Replay Access

Webcast replay will be available for approximately 30 days at www.targetedgenetics.com; telephone replay will be available following Tuesday's call at approximately 10:30 a.m. PT through 11:59 p.m. PT, Saturday, April 26, 2008, by calling 800.405.2236 (domestic) or 303.590.3000 (international); pass code 11110469#.

About Targeted Genetics

Targeted Genetics Corporation is a biotechnology company committed to the development of innovative targeted molecular therapies for the prevention and treatment of acquired and inherited diseases with significant unmet medical need. Targeted Genetics' proprietary Adeno-Associated Virus (AAV) technology platform allows it to deliver genes that encode proteins to increase gene function or RNAi to decrease or silence gene function. Targeted Genetics' product development efforts target inflammatory arthritis, AIDS prophylaxis, congestive heart failure and Huntington's disease. To learn more about Targeted Genetics, visit Targeted Genetics' website at www.targetedgenetics.com.

Investor and Media Contacts: Stacie D. Byars Senior Associate WeissComm Partners 415.946.1072 Carolyn Wang Senior Associate WeissComm Partners 415.946.1065

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