FORM 4
[ X ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

GREAT POINT PARTNERS LLC
2. Issuer Name and Ticker or Trading Symbol

MEDecision, Inc. [ MEDE ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      __ X __ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

, 165 MASON STREET, 3RD FLOOR
3. Date of Earliest Transaction (MM/DD/YYYY)

7/1/2008
(Street)

GREENWICH, CT 06830
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   7/1/2008     P (1)    161755   A $6.65   1132297   I   By Biomedical Value Fund, L.P.   (2)
Common Stock   7/7/2008     S    15871   D $6.6115   1116426   I   By Biomedical Value Fund, L.P.   (2)
Common Stock   7/8/2008     S    11129   D $6.5829   1105297   I   By Biomedical Value Fund, L.P.   (2)
Common Stock   7/8/2008     S    77223   D $6.5829   1028074   I   By Biomedical Value Fund, L.P.   (2)
Common Stock   7/8/2008     S    31500   D $6.5670   996574   I   By Biomedical Value Fund, L.P.   (2)
Common Stock   7/1/2008     S (1)    161755   D $6.65   665000   I   By Biomedical Offshore Value Fund, Ltd.   (3)
Common Stock   7/7/2008     S    9321   D $6.6115   655679   I   By Biomedical Offshore Value Fund, Ltd.   (3)
Common Stock   7/8/2008     S    51888   D $6.5829   603791   I   By Biomedical Offshore Value Fund, Ltd.   (3)
Common Stock   7/8/2008     S    9336   D $6.5700   594455   I   By Biomedical Offshore Value Fund, Ltd.   (3)
Common Stock   7/8/2008     S    9164   D $6.5700   585291   I   By Biomedical Offshore Value Fund, Ltd.   (3)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
( 1)  On July 1, 2008, Biomedical Offshore Value Fund, Ltd. ("BOVF") sold 161,755 shares of Common Stock of MEDecision, Inc. to Biomedical Value Fund, L.P. ("BMVF") at a purchase price of $6.65 per share. The purchase price was the closing market price for the shares on June 30, 2008.
( 2)  Great Point Partners, LLC ("Great Point") is the investment manager of BMVF and by virtue of such status may be deemed to be the beneficial owner of the shares held by BMVF. Each of Dr. Jeffrey R. Jay, M.D. ("Dr. Jay"), as senior managing member of Great Point, and Mr. David Kroin ("Mr. Kroin"), as special managing member of Great Point, has voting and investment power with respect to the shares held by BMVF and may be deemed to be the beneficial owner of the shares held by BMVF. Great Point, Dr. Jay and Mr. Kroin disclaim beneficial ownership of the shares held by BMVF, except to the extent of any pecuniary interest, and this report shall not be deemed to be an admission that they are the beneficial owners of such securities.
( 3)  Great Point is the investment manager of BOVF and by virtue of such status may be deemed to be the beneficial owner of the shares held by BOVF. Each of Dr. Jay, as senior managing member of Great Point, and Mr. Kroin, as special managing member of Great Point, has voting and investment power with respect to the shares held by BOVF and may be deemed to be the beneficial owner of the shares held by BOVF. Great Point, Dr. Jay and Mr. Kroin disclaim beneficial ownership of the shares held by BOVF, except to the extent of any pecuniary interest, and this report shall not be deemed to be an admission that they are the beneficial owners of such securities.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
GREAT POINT PARTNERS LLC
165 MASON STREET, 3RD FLOOR
GREENWICH, CT 06830

X

JAY JEFFREY R
GREAT POINT PARTNERS, LLC
165 MASON STREET, 3RD FLOOR
GREENWICH, CT 06830

X

KROIN DAVID
C/O GREAT POINT PARTNERS LLC
165 MASON STREET, 3RD FLOOR
GREENWICH, CT 06830

X


Signatures
/s/ Dr. Jeffrey R. Jay, M.D., as senior managing member 7/9/2008
** Signature of Reporting Person Date

/s/ Dr. Jeffrey R. Jay, M.D. 7/9/2008
** Signature of Reporting Person Date

/s/ Mr. David Kroin 7/9/2008
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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