PTP Profile Thera.

RNS Number:7237W
3i Investments PLC
19 March 2004

                                                                      FORM SAR 5



Lodge with Company Announcements Office and the Panel.
A copy must also be sent to the company the shares of which are being sold.


Date of disclosure


19.03.04



DISCLOSURE UNDER NOTE 3 OF RULE 5 OF THE RULES GOVERNING SUBSTANTIAL
ACQUISITIONS OF SHARES ("SARs")



Date of sale


18.03.04



Sale of (name of company)


Profile Therapeutics  plc



1. Class of voting shares (eg ordinary shares)


Ordinary 2p shares



Number of shares/rights over shares sold


1,000,000                    Shares                    Rights



If rights over shares sold, as opposed to the shares themselves, specify nature
of rights



2. Resultant total holding of voting shares (and % of total voting shares in
issue)

9,516,384                                               19.38 %


Resultant total holding of rights over shares (and % of total voting shares in
issue)
                                                       %

Total percentage


19.38  %



3. Party making disclosure


3i Investments plc

4. (a) Name of person selling shares or rights over shares


3i Investments plc



and, if different, beneficial owner



(b) Names of any other persons acting by agreement or understanding



Signed, for and on behalf of the party named in (3) above




(Also print name of signatory)


Simon Howard



Telephone and extension number


020 7928 3131



For full details of the SARs disclosure requirements, see Rules 3 and 5 of the
SARs.  If in doubt, contact the Panel on Takeovers and Mergers, Monitoring
Section, Tel. No: 020 7638 0129.


                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

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