RNS No 1877h
OXFORD INSTRUMENTS PLC
16th March 1999

Letter to  Company Announcements Office

The Company has been notified today for the purposes of S.198 Companies Act
1985: as amended by the Disclosure of Interest in Shares (Amendment)
Regulations 1993 that Phillips & Drew Life Limited has a notifiable interest
in 1,745,250 Ordinary Shares of 5p each which, represents 3.65% of the issued
share capital of Oxford Instruments plc.

The shares to which this notification relates are registered as follows:

Registered Holder                  Number of Shares

Phildrew Nominees Limited a/c LF06 - 13,740

Phildrew Nominees Limited a/c LF20 - 1,731,510

TOTAL                              - 1,745,250

Phillips & Drew Life Limited is a subsidiary of Phillips & Drew Holding
Limited which is also treated as having an interest in the above shares.


Letter from   Della Gorham (Mrs)
              Assistant Company Secretary
              Oxford Instruments Plc


END

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