RNS Number:5129O
Cytomyx Holdings PLC
21 December 2006

                              Cytomyx Holdings Plc

                            Directors' Shareholding



The Company has been notifed that Dr Wei-Wu He, chief executive, has purchased
an aggregate 3,600,000 ordinary shares of 2.5 pence each in the company, which
represents his entire interest.



The purchases were denominated in US $ and made as follows:


Date of purchase     Number of Shares acquired         Price per share ($)
15/12/2006           900,000                           0.03
08/12/2006           900,000                           0.026
06/12/2006           1,000,000                         0.025
01/12/2006           800,000                           0.0237




                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

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