As filed with the U.S. Securities and Exchange
Commission on October 29, 2024.
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-3
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
TRISALUS LIFE SCIENCES, INC.
(Exact name of registrant as specified in its charter)
Delaware
(State or other jurisdiction of
incorporation or organization) |
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3841
(Primary Standard Industrial
Classification Code Number) |
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85-3009869
(I.R.S. Employer
Identification No.) |
6272 W. 91st Ave.
Westminster, Colorado 80031
(888) 321-5212
(Address, including zip code, and telephone number,
including area code, of registrant’s principal executive offices)
Mary Szela
Chief Executive Officer
6272 W. 91st Ave.
Westminster, Colorado 80031
(888) 321-5212
(Name, address, including zip code, and telephone
number, including area code, of agent for service)
Copy to:
Matt Browne
Carlos Ramirez
Cooley LLP
10265 Science Center Dr
San Diego, California 92121
(858) 550-6000
Approximate date of commencement of proposed
sale to the public:
From time to time on or after this registration
statement is declared effective.
If the only securities being
registered on this Form are being offered pursuant to dividend or interest reinvestment plans, please check the following box: ☐
If any of the securities
being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act
of 1933, other than securities offered only in connection with dividend or interest reinvestment plans, check the following box. ☒
If this Form is filed
to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following
box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐
If this Form is a post-effective
amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration
statement number of the earlier effective registration statement for the same offering. ☐
If this Form is a registration
statement pursuant to General Instruction I.D. or a post-effective amendment thereto that shall become effective upon filing with the
Commission pursuant to Rule 462(e) under the Securities Act, check the following box. ☐
If this Form is a post-effective
amendment to a registration statement filed pursuant to General Instruction I.D. filed to register additional securities or additional
classes of securities pursuant to Rule 413(b) under the Securities Act, check the following box. ☐
Indicate by check mark whether
the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging
growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting
company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
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Large accelerated filer |
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Accelerated filer |
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Non-accelerated filer |
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Smaller reporting company |
x |
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Emerging growth company |
x |
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If an emerging growth company,
indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial
accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐
The
registrant hereby amends this registration statement on such date or dates as may be necessary to delay its effective date until the registrant
shall file a further amendment which specifically states that this registration statement shall thereafter become effective in accordance
with Section 8(a) of the Securities
Act of 1933 or until the registration statement shall become effective
on such date as the Securities and Exchange Commission, acting pursuant to said Section 8(a),
may determine.
The information in this preliminary
prospectus is not complete and may be changed. Neither we nor the selling securityholders may not sell these shares of Common Stock until
the registration statement filed with the Securities and Exchange Commission is effective. This preliminary prospectus is not an offer
to sell these shares of Common Stock, and neither we nor the selling securityholders seek an offer to buy these shares of our Common
Stock in any jurisdiction where the offer or sale is not permitted.
Subject to Completion, Dated October 29,
2024
PRELIMINARY PROSPECTUS
![](https://www.sec.gov/Archives/edgar/data/1826667/000110465924112293/tm2426916d4_img001.jpg)
Up to 10,587,582 Shares of Common Stock
This
prospectus relates to the offer and sale, from time to time, by the Selling Securityholders named in this prospectus or their permitted
transferees (the “Selling Securityholders”) of up to 10,587,582 shares of our common stock, $0.0001 par value
per share (the “Common Stock”), issued pursuant to the Agreement and Plan of Merger (the “Merger Agreement”),
dated as of November 11, 2022, as amended on April 4, 2023, May 13, 2023 and July 5, 2023, by and among MTAC, MTAC
Merger Sub, Inc. and TriSalus Operating Life Sciences, Inc. (“Legacy TriSalus”) to the Selling Securityholders.
The Selling Securityholders
are “underwriters” within the meaning of Section 2(a)(11) of the Securities Act of 1933, as amended (the “Securities
Act”), and any profits on the sales of shares of our Common Stock by the Selling Securityholders and any discounts, commissions,
or concessions received by the Selling Stockholders are deemed to be underwriting discounts and commissions under the Securities Act.
The Selling Securityholders may offer and sell the shares of Common Stock covered by this prospectus from time to time. The Selling Securityholders
may offer and sell the shares of Common Stock covered by this prospectus in a number of different ways and at varying prices.
The Selling
Securityholders may sell the shares of Common Stock being offered for resale through various methods, as described in the section
titled “Plan of Distribution.” These sales may be at fixed prices, at prevailing market prices at the time of
sale, at prices related to the prevailing market price, at varying prices determined at the time of sale, or at negotiated prices.
In connection with any sales of shares of Common Stock offered hereunder, the Selling Securityholders and any underwriters, agents,
brokers or dealers participating in such sales will be deemed to be “underwriters” within the meaning of the Securities
Act of 1933, as amended. We will bear all costs, expenses and fees in connection with the registration of these shares of Common
Stock, including with regard to compliance with state securities or “blue sky” laws. The Selling Securityholders will
bear all commissions and discounts, if any, attributable to their sale of shares of Common Stock. See the section titled
“Plan of Distribution.” We will not receive any of the proceeds from such sales of the shares of Common Stock by
the Selling Securityholders pursuant to this prospectus.
The Common Stock
is listed on the Nasdaq Global Market under the ticker symbols “TLSI.” On October 21, 2024, the last reported sales price
of our Common Stock was $4.25 per share.
We are an “emerging
growth company” as defined under U.S. federal securities laws and, as such, have elected to comply with reduced public company reporting
requirements. This prospectus complies with the requirements that apply to an issuer that is an emerging growth company. We are incorporated
in Delaware.
Investing in
our shares of Common Stock involves a high degree of risk. You should review carefully the risks and uncertainties described in the section
titled “Risk Factors” beginning on page 4 of this prospectus, and under similar headings in any amendments or
supplements to this prospectus.
Neither the
Securities and Exchange Commission nor any state securities commission has approved or disapproved of these shares of Common Stock, or
passed upon the accuracy or adequacy of this prospectus. Any representation to the contrary is a criminal offense.
Prospectus dated ,
2024
TABLE
OF CONTENTS
For investors outside of
the United States: Neither we, nor the Selling Securityholders, have done anything that would permit this offering or possession or distribution
of this prospectus in any jurisdiction where action for that purpose is required, other than in the United States. Persons outside the
United States who come into possession of this prospectus must inform themselves about, and observe any restrictions relating to, the
offering of our shares of Common Stock and the distribution of this prospectus outside the United States.
To the extent there is a
conflict between the information contained in this prospectus, on the one hand, and the information contained in any document incorporated
by reference filed with the U.S. Securities and Exchange Commission (the “SEC”) before the date of this prospectus, on the other hand, you should rely on the information in this prospectus.
If any statement in a document incorporated by reference is inconsistent with a statement in another document incorporated by reference
having a later date, the statement in the document having the later date modifies or supersedes the earlier statement.
ABOUT
THIS PROSPECTUS
This prospectus is part of
a registration statement on Form S-3 that we filed with the SEC using the “shelf” registration process. Under this shelf
registration process, the Selling Securityholders may, from time to time, sell the shares of Common Stock offered by them described in
this prospectus. We will not receive any proceeds from the sale by such Selling Securityholders of the shares of Common Stock offered
by them described in this prospectus.
Neither we nor the Selling
Securityholders have authorized anyone to provide you with any information or to make any representations other than those contained in
this prospectus or any applicable prospectus supplement or any free writing prospectuses prepared by or on behalf of us or to which we
have referred you. Neither we nor the Selling Securityholders take responsibility for and can provide no assurance as to the reliability
of, any other information that others may give you. Neither we nor the Selling Securityholders will make an offer to sell these shares
of Common Stock in any jurisdiction where the offer or sale is not permitted.
We may also provide a prospectus
supplement or post-effective amendment to the registration statement to add information to, or update or change information contained
in, this prospectus. You should read both this prospectus and any applicable prospectus supplement or post-effective amendment to the
registration statement together with the additional information to which we refer you in the section titled “Where You Can Find
More Information” and “Incorporation of Certain Information by Reference” before deciding to invest in any
of the shares of Common Stock being offered. The information contained in this prospectus and any supplement to this prospectus, or incorporated
by reference herein, is accurate only as of the respective dates thereof, regardless of the time of delivery of this prospectus or of
any sale of our shares of Common Stock. Our business, financial condition, results of operations and prospects may have changed since
those dates.
On August 10, 2023,
Legacy TriSalus, MTAC and Merger Sub consummated the transactions contemplated by the Merger Agreement (as such terms are defined below),
following the approval by MTAC’s stockholders at an extraordinary general meeting held on August 2, 2023. Pursuant to the terms
of the Merger Agreement, a Business Combination (as defined below) of Legacy TriSalus and MTAC was effected through, among other transactions,
the merger of Merger Sub with and into Legacy TriSalus with the separate corporate existence of Merger Sub ceasing. In connection with
the consummation of the Merger on August 10, 2023, MTAC changed its name from MedTech Acquisition Corporation to TriSalus Life Sciences, Inc.
and Legacy TriSalus changed its name from TriSalus Life Sciences, Inc. to TriSalus Operating Life Sciences, Inc.
Unless the context indicates
otherwise, references in this prospectus to the “Company,” “TriSalus,” “we,” “us,” “our”
and similar terms refer to TriSalus Life Sciences, Inc. (f/k/a MedTech Acquisition Corporation) and its consolidated subsidiaries
(including Legacy TriSalus). References to “MTAC” refer to the predecessor company prior to the consummation of the Business
Combination.
SPECIAL
NOTE REGARDING FORWARD-LOOKING STATEMENTS
This prospectus and the documents
incorporated by reference herein and any prospectus supplement delivered with this prospectus may contain forward-looking statements within
the meaning of the federal securities laws. Forward-looking statements relate to expectations, beliefs, projections, future plans and
strategies, anticipated events or trends and similar expressions concerning matters that are not historical facts. These forward-looking
statements include statements regarding our intentions, beliefs and current expectations and projections concerning, among other things,
our results of operations, financial condition, liquidity, prospects, growth, strategies and the markets in which we operate. In some
cases, you can identify these forward-looking statements by the use of terminology such as “outlook,” “believes,”
“expects,” “potential,” “continues,” “may,” “will,” “should,”
“could,” “seeks,” “approximately,” “predicts,” “intends,” “plans,”
“estimates,” “anticipates” or the negative version of these words or other comparable words or phrases.
The forward-looking statements
contained in this prospectus reflect our current views about future events and are subject to numerous known and unknown risks, uncertainties,
assumptions and changes in circumstances that may cause its actual results to differ materially from those expressed in any forward-looking
statement. There are no guarantees that the transactions and events described will happen as described (or that they will happen at all).
As a result of a number of known and unknown risks and uncertainties, our actual results or performance may be materially different from
those expressed or implied by these forward-looking statements. Some factors that could cause actual results to differ include:
| · | our ability to raise financing in the future; |
| · | our
ability to service our indebtedness and to access additional delayed draws that may in the
future become available to us; |
| · | changes
in applicable laws or regulations; |
| · | our
ability to retain or recruit, or changes required in, our officers, key employees or directors; |
| · | our
ability to successfully commercialize any product candidates that we successfully develop
and that are approved by applicable regulatory authorities; |
| · | our
expectations for the timing and results of data from clinical trials and regulatory approval
applications; |
| · | our
estimates regarding expenses, future revenue, capital requirements and needs for additional
financing; |
| · | our
business, operations and financial performance including: |
| · | our
history of operating losses and expectations of significant expenses and continuing losses
for the foreseeable future; |
| · | our
ability to execute our business strategy, including the growth potential of the markets for
our products and our ability to serve those markets; |
| · | our
ability to grow market share in our existing markets or any new markets we may enter; |
| · | our
ability to develop and maintain our brand and reputation; |
| · | our
ability to partner with other companies; |
| · | the
size of the addressable markets for our product candidates; |
| · | our
expectations regarding our ability to obtain and maintain intellectual property protection
and not infringe on the rights of others; |
| · | our
ability to manage our growth effectively; |
| · | our
ability to maintain the listing of our securities in the Nasdaq Global Market, and the potential
liquidity and trading of such securities; |
| · | the
outcome of any legal proceedings that may be instituted against us; and |
| · | unfavorable
conditions in our industry, the global economy or global supply chain, including financial
and credit market fluctuations, international trade relations, pandemics, political turmoil,
natural catastrophes, warfare and terrorist attacks. |
In addition, statements
that “TriSalus believes,” “the Company believes” or “we believe” and similar statements reflect
our beliefs and opinions on the relevant subjects. These statements are based upon information available to us as of the date of
this prospectus or the date of the applicable information incorporated by reference in this prospectus, and while we believe such information forms a reasonable basis for such statements, such information may be
limited or incomplete, and such statements should not be read to indicate that we have conducted an exhaustive inquiry into, or
review of, all potentially available relevant information. These statements are inherently uncertain and investors are cautioned not
to unduly rely upon these statements.
While forward-looking statements
reflect our good faith beliefs, they are not guarantees of future performance. Except to the extent required by applicable law, we are
under no obligation (and expressly disclaim any such obligation) to update or revise their forward-looking statements whether as a result
of new information, future events, or otherwise. For a further discussion of these and other factors that could cause our future results,
performance or transactions to differ significantly from those expressed in any forward-looking statement, please see the section titled
“Risk Factors.” You should not place undue reliance on any forward-looking statements, which are based only on information
currently available to us (or to third parties making the forward-looking statements).
You should read this prospectus
and any accompanying prospectus supplement and the documents incorporated by reference herein or therein completely and with the understanding that our actual future results, levels of activity and
performance as well as other events and circumstances may be materially different from what we expect. We qualify all of our forward-looking
statements by these cautionary statements.
FREQUENTLY
USED TERMS
“Business Combination”
means the transactions contemplated by the Merger Agreement, including, among other things, the Merger.
“Bylaws”
mean our amended and restated bylaws.
“Certificate of
Incorporation” means the Second Amended and Restated Certificate of Incorporation.
“Closing”
means the closing of the Business Combination.
“Closing Date”
means August 10, 2023, the date on which the Closing occurred.
“Common Stock”
means the shares of our common stock, $0.0001 par value per share.
“DGCL”
means the General Corporation Law of the State of Delaware.
“Initial
OrbiMed Warrant” means the 130,805 warrants issued to OrbiMed in connection with the initial draw down of a loan under the Credit
Agreement dated April 30, 2024, between the Company and OrbiMed, all of which remain outstanding as of October 21,
2024.
“Founder Shares”
means the 4,062,500 shares of Common Stock issued to the members of the Sponsor that were not forfeited at Closing.
“Legacy TriSalus”
means TriSalus Operating Life Sciences, Inc., a Delaware corporation which, pursuant to the Business Combination, became a direct,
wholly owned subsidiary of TriSalus Life Sciences, Inc., and, unless the context otherwise requires, its consolidated subsidiaries.
“Merger”
means the merger of Merger Sub, a direct, wholly owned subsidiary of MTAC, with and into Legacy TriSalus, with Legacy TriSalus continuing
as the surviving entity.
“Merger Agreement”
means that certain Agreement and Plan of Merger, dated as of November 11, 2022, as amended by that certain First Amendment to Agreement
and Plan of Merger, dated as of April 4, 2023, the Second Amendment to Agreement and Plan of Merger, dated as of May 13, 2023,
and the Third Amendment to Agreement and Plan of Merger, dated as of July 5, 2023, with Merger Sub and Legacy TriSalus.
“Merger Sub”
means MTAC Merger Sub, Inc., a Delaware corporation and wholly-owned subsidiary of MTAC.
“MTAC”
means MedTech Acquisition Corporation (which was renamed “TriSalus Life Sciences, Inc” in connection with the consummation
of the Business Combination).
“MTAC IPO”
means MTAC’s initial public offering, consummated on December 22, 2020.
“OrbiMed” means
OrbiMed Royalty & Credit Opportunities IV, LP and certain of its affiliates.
“Private Placement
Warrants” means the 4,933,333 warrants purchased by the Sponsor in connection with the MTAC IPO in a private placement transaction
occurring simultaneously with the closing of the MTAC IPO, of which 4,428,648 remained outstanding as of October 21, 2024.
“Public
Warrants” means the 8,281,779 outstanding warrants included as a component of the MTAC Units sold in the MTAC IPO, each of which
is exercisable, at an exercise price of $11.50, for one share of Common Stock, in accordance with its terms, of which 1,751,825 remained
outstanding as of October 21, 2024.
"SEPA" means the
Standby Equity Purchase Agreement, dated October 2, 2023, by and between TriSalus Life Sciences, Inc. and Yorkville.
“Sponsor”
means MedTech Acquisition Sponsor LLC, a Delaware limited liability company, which liquidated and distributed its holdings to its ultimate
beneficiaries prior to the Closing.
“Working
Capital Warrants” means the 1,000,000 warrants issued upon the conversion of the promissory note issued by MTAC to the Sponsor
for working capital requirements and payment of certain expenses in connection with the Business Combination, all of which remained outstanding
as of October 21, 2024.
"Yorkville" means
YA II PN, Ltd.
PROSPECTUS
SUMMARY
This summary
highlights information contained elsewhere in this prospectus and does not contain all of the information that you should consider
in making your investment decision. Before investing in our shares of Common Stock, you should carefully read this entire
prospectus, including our consolidated financial statements and the related notes thereto and the information set forth in the
section titled “Risk Factors” or incorporated by reference therein or otherwise incorporated by reference or included
elsewhere in this prospectus, before deciding to invest in our shares of common stock. For purposes of this section, unless
otherwise indicated or the context otherwise requires, all references to “TriSalus,” “the Company,”
“we,” “our,” “ours,” “us” or similar terms refer to TriSalus Life
Sciences, Inc. and its consolidated subsidiaries after the Closing.
Overview
We are a growing, oncology
focused medical technology business bringing disruptive drug delivery technology with the goal of improving therapeutic delivery to liver
and pancreatic tumors. Additionally, we are exploring the integration of our technology with our investigational immunotherapeutic, nelitolimod,
a class C Toll-like receptor 9 agonist, for a range of liver and pancreatic indications. Our ultimate goal is to transform the treatment
paradigm for patients battling liver and pancreatic tumors. We have developed an innovative organ-specific platform that is designed to
overcome two of the most significant challenges that prevent optimal delivery and performance of therapeutics in these difficult-to-treat
diseases: (i) high intratumoral pressure caused by tumor growth and collapsed vasculature restricting the delivery of oncology therapeutics
and (ii) the immunosuppressive properties of liver and pancreatic tumor immune cells. By systematically addressing these barriers,
we aim to improve response to therapies and to enable improved patient outcomes.
Implications of Being an Emerging Growth Company
and a Smaller Reporting Company
We are an emerging growth
company, as defined in the Jumpstart Our Business Startups Act of 2012, as amended, and therefore we intend to take advantage of certain
exemptions from various public company reporting requirements, including not being required to have our internal control over financial
reporting audited by our independent registered public accounting firm pursuant to Section 404(b) of the Sarbanes-Oxley Act
of 2002, reduced disclosure obligations regarding executive compensation in this prospectus, our periodic reports and our proxy statements
and exemptions from the requirements of holding a nonbinding advisory vote on executive compensation and any golden parachute payments
not previously approved. We will remain an emerging growth company until the earliest of (i) the last day of the fiscal year
in which the market value of our Common Stock that is held by non-affiliates equals or exceeds $700 million as of the end of that year’s
second fiscal quarter, (ii) the last day of the fiscal year in which we have total annual gross revenue of $1.235 billion
or more during such fiscal year (as indexed for inflation), (iii) the date on which we have issued more than $1.0 billion
in non-convertible debt in the prior three-year period or (iv) December 31, 2025.
We are also a smaller reporting
company as defined in the Securities Exchange Act of 1934, as amended (the “Exchange Act”). We may continue to be a smaller
reporting company even after we are no longer an emerging growth company. We may take advantage of certain of the scaled disclosures available
to smaller reporting companies and will be able to take advantage of these scaled disclosures for so long as (i) the market value
of our common stock held by non-affiliates exceeds $250 million as of the end of that year’s second fiscal quarter, or (ii) our
annual revenues exceeded $100 million during such completed fiscal year and the market value of common stock held by non-affiliates equals
or exceeds $700 million as of the end of that year’s second fiscal quarter.
Corporate Information
Our principal executive offices
are located at 6272 W. 91st Ave., Westminster, Colorado 80031 and our telephone number is (888) 321-5212. Our corporate website address
is www.trisaluslifesci.com. Information contained on or accessible through our website is not a part of this prospectus, and the inclusion
of our website address in this prospectus is an inactive textual reference only.
We and our subsidiaries own
or have rights to trademarks, trade names and service marks that they use in connection with the operation of their business. Other trademarks,
trade names and service marks appearing in this prospectus are the property of their respective owners. Solely for convenience, in some
cases, the trademarks, trade names and service marks referred to in this prospectus are listed without the applicable ®,
™ and SM symbols.
THE
OFFERING
Shares of Common Stock offered by the Selling Securityholders |
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We
are registering the resale by the Selling Securityholders named in this prospectus, or their permitted transferees, an aggregate of 10,587,582
shares of Common Stock.
Given the substantial number of shares of Common Stock being registered
for potential resale by Selling Securityholders pursuant to this prospectus, the sale of shares by Selling Securityholders of a large
number of shares, or the perception in the market that the Selling Securityholders intend to sell a large number of shares, could increase
the volatility of the market price of our Common Stock or result in a significant decline in the public trading price of our Common Stock. |
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Terms of the offering |
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The Selling Securityholders will determine when and how they will dispose of the shares of Common Stock registered for resale under this prospectus. |
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Use of proceeds |
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We will not receive any proceeds from the sale of shares of Common Stock by the Selling Securityholders. |
Risk factors |
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Before investing in our shares of Common Stock, you should carefully read and consider the information set forth in the section titled “Risk Factors” beginning on page 4 of this prospectus and the documents incorporated herein by reference. |
Nasdaq ticker symbols |
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“TLSI” |
The number of shares of Common
Stock outstanding is based on 30,491,072 shares of Common Stock outstanding as of October 21, 2024 and excludes:
| · | 1,751,825 shares of Common Stock issuable upon the exercise of outstanding Public Warrants; |
| · | 4,428,648 shares of Common Stock issuable upon the exercise of outstanding Private Placement Warrants; |
| · | 1,000,000 shares of Common Stock issuable upon the exercise of outstanding Working Capital Warrants; |
| · | 130,805 shares of Common Stock issuable upon the exercise of the Initial OrbiMed Warrant; |
| · | 25,207,155 shares of Common Stock issuable upon conversion of Series A Convertible Preferred Stock,
assuming conversion of all outstanding Series A Convertible Preferred Stock at its floor price; |
| · | 7,969,524 shares of Common Stock available for future issuance under the Company’s 2023 Equity Incentive
Plan; |
| · | 2,308,867 shares of Common Stock available for future issuance under the Company’s 2023 Employee
Stock Purchase Plan; and |
| · | 3,385,837 shares of Common Stock that we may elect, in our sole discretion, to issue and sell to Yorkville
from time to time under the SEPA. |
For additional information
concerning the offering, see the section titled “Plan of Distribution” beginning on page 10 of this prospectus.
RISK
FACTORS
Investing
in our shares of Common Stock involves a high degree of risk. Before you make a decision to buy our shares of Common Stock, you
should carefully review the risks and uncertainties described under the heading “Risk Factors” contained in our most recent
Annual Report on Form 10-K, as updated by our subsequent Quarterly Reports on Form 10-Q and other filings we make
with the Securities and Exchange Commission, or the SEC, which are incorporated by reference into this prospectus in their entirety together
with other information in this prospectus and the documents incorporated by reference. The risks described in these documents are not
the only ones we face, but those that we consider to be material. There may be other unknown or unpredictable economic, business, competitive,
regulatory or other factors that could have material adverse effects on our future results. Past financial performance may not be a reliable
indicator of future performance, and historical trends should not be used to anticipate results or trends in future periods. If any of
these risks actually occur, our business, financial condition, results of operations or cash flow could be seriously harmed. This could
cause the trading price of our Common Stock to decline, resulting in a loss of all or part of your investment. Additional risks not presently
known to us or that we currently believe are immaterial may also significantly impair our business operations. Please also read carefully
the section above titled “Special Note Regarding Forward-Looking Statements.”
RISKS
RELATED TO THIS OFFERING
Sales of our Common Stock or the perception
of such sales, by us or the Selling Securityholders pursuant to this prospectus, in the public market or otherwise, could cause the market
price for our securities to decline, even though the Selling Securityholders would still realize a profit on sales at lower prices. Resales
of the securities offered by this prospectus may cause the market price of such securities to drop significantly, even if our business
is doing well.
The sale of our Common Stock
in the public market or otherwise, including sales pursuant to this prospectus, or the perception that such sales could occur, could harm
the prevailing market price of our Common Stock. These sales, or the possibility that these sales may occur, also might make it more difficult
for us to sell equity securities in the future at a time and at a price that we deem appropriate. Resales of our Common Stock may cause
the market price of our securities to drop significantly, even if our business is doing well.
Certain of the Selling Securityholders
named in this prospectus acquired securities at prices that are significantly less than the current trading price of our Common Stock.
Accordingly, certain of the Selling Securityholders could still realize a profit on sales at lower prices.
In addition, the Selling Securityholders named in this prospectus hold a disproportionately large portion of our outstanding Common Stock. The Common Stock being
offered for resale pursuant to this prospectus by the Selling Securityholders would represent approximately 34.7% of our outstanding Common
Stock as of October 21, 2024. Given the substantial number of shares of Common Stock being registered for potential resale by Selling
Securityholders pursuant to this prospectus, the sale of shares by the Selling Securityholders of a large number of shares, or the perception
in the market that the Selling Securityholders of a large number of shares intend to sell shares, could increase the volatility of the
market price of our Common Stock or result in a significant decline in the public trading price of our Common Stock. The Selling Securityholders
will be able to sell all of their securities held and registered for resale under the registration statement of which this prospectus
forms a part for so long as such registration statement is in effect. Even if the trading price of our Common Stock falls to or significantly
below the current trading price, the Selling Securityholders may still have an incentive to sell and profit due to the nominal purchase
prices paid by such Selling Securityholders, which are significantly lower than the purchase prices paid by the public securityholders.
Certain of our Selling Securityholders acquired the Common Stock at prices that are significantly lower than the current trading price
of our Common Stock.
USE
OF PROCEEDS
All
of the shares of Common Stock offered by the Selling Securityholders pursuant to this prospectus will be sold by the Selling Securityholders
for their respective accounts. We will not receive any of the proceeds from these sales. We will pay the expenses associated with
the registration of the shares of Common Stock as described in the “Plan of Distribution” section in this prospectus.
SELLING
SECURITYHOLDERS
This
prospectus relates to the offer and sale, from time to time, by the Selling Securityholders named in this prospectus or their permitted
transferees of up to 10,587,582 shares of Common Stock issued to the Selling Securityholders pursuant to the Merger Agreement.
The Selling Securityholders may from time to time offer and sell any or all of the Common Stock set forth below pursuant to this prospectus
and any accompanying prospectus supplement. As used in this prospectus, the term “Selling Securityholders” includes
the persons listed in the table below, together with any additional Selling Securityholders listed in any subsequent amendment to this prospectus,
and their pledgees, donees, transferees, assignees, successors, designees and others who later come to hold any of the Selling Securityholders’
interests in the Common Stock other than through a public sale.
Except as set forth in the
footnotes below, the following table sets forth, based on written representations from the Selling Securityholders, certain information
as of October 21, 2024, regarding the beneficial ownership of our Common Stock by the Selling Securityholders and the shares of Common
Stock being offered by the Selling Securityholders. The applicable percentage ownership of Common Stock is based on approximately 30,491,072
shares of Common Stock outstanding as of October 21, 2024. Information with respect to shares of Common Stock owned beneficially
after the offering assumes the Selling Securityholders sell all of the shares of Common Stock covered by this prospectus and do not acquire
beneficial ownership of any additional shares of Common Stock. The Selling Securityholders may offer and sell some, all or none of their
shares of Common Stock.
We have determined beneficial
ownership in accordance with the rules of the SEC, which generally provide that a person has beneficial ownership of a security if
he, she or it possesses sole or shared voting or investment power over that security or the right to acquire such power within 60 days.
Except as indicated by the footnotes below, we believe, based on the information furnished to us, that the Selling Securityholders have
sole voting and investment power with respect to all shares of Common Stock that they beneficially own, subject to applicable community
property laws. Except as otherwise described below, based on the information provided to us by the Selling Securityholders, no Selling
Securityholders is a broker-dealer or an affiliate of a broker dealer.
Please see the section titled
“Plan of Distribution” for further information regarding the Selling Securityholders’ method of distributing
these shares.
| |
Shares of Common Stock | |
| |
Number | | |
Number | | |
Number | | |
| |
| |
Beneficially | | |
Registered | | |
Beneficially | | |
Percent | |
| |
Owned | | |
for | | |
Owned | | |
Owned | |
| |
Prior to | | |
Sale | | |
After | | |
After | |
Name of Selling Securityholder | |
Offering | | |
Hereby | | |
Offering | | |
Offering | |
Frankenius Equity AB(1) | |
| 6,191,072 | | |
| 6,167,776 | | |
| 23,296 | | |
| * | |
Mats L. Wahlstrom(2) | |
| 2,792,626 | | |
| 1,254,259 | | |
| 168,339 | | |
| * | |
Bryan Cox(3) | |
| 93,427 | | |
| 67,817 | | |
| 25,610 | | |
| * | |
HW Investment Partners, LLC(4) | |
| 1,370,028 | | |
| 1,370,028 | | |
| 0 | | |
| * | |
Jennifer Stevens(5) | |
| 70,785 | | |
| 13,904 | | |
| 56,881 | | |
| * | |
Mary T. Szela(6) | |
| 833,447 | | |
| 243,189 | | |
| 590,258 | | |
| 1.9 | % |
Richard Marshak(7) | |
| 81,989 | | |
| 8,372 | | |
| 73,617 | | |
| * | |
Kerry Hicks(8) | |
| 2,319,570 | | |
| 919,171 | | |
| 30,371 | | |
| * | |
Sean Murphy(9) | |
| 658,382 | | |
| 525,267 | | |
| 133,115 | | |
| * | |
Steven Katz(10) | |
| 210,103 | | |
| 17,799 | | |
| 192,304 | | |
| * | |
* Less
than one percent.
| (1) | The shares registered for resale hereby represent 6,167,776 shares of Common Stock held by Frankenius
Equity AB (“Frankenius”). In addition, 1,699,010 shares of Common Stock issuable upon conversion of shares of Series A
Convertible Preferred Stock held by Frankenius (with 253,296 shares of Common Stock issuable within 60 days) are not registered for resale
by this prospectus. Frankenius’ principal place of business is Box 984, 501 10 Boras, Sweden. Paul Frankenius has sole voting and
investment discretion with respect to the shares held directly by Frankenius and may be deemed to have beneficial ownership of the shares
held by Frankenius. |
| (2) | The shares registered for resale hereby represent 1,254,259 shares of Common Stock held by Leonard Capital
LLC and 1,370,028 shares of Common Stock held by HW Investment Partners, LLC (“HW Investment”). In addition, (i) 319,349
shares of Common Stock issuable upon conversion of shares of Series A Convertible Preferred Stock held by Leonard Capital LLC (with
55,064 shares of Common Stock issuable within 60 days), and (ii) 185,945 shares of Common Stock issuable upon the exercise of stock
options (113,275 of which are exercisable within 60 days) are not registered for resale by this prospectus. Mr. Wahlström has
sole voting and investment discretion with respect to the shares held directly by Leonard Capital LLC and shared voting and investment
discretion with respect to the shares held directly by HW Investment and may be deemed to have beneficial ownership of the shares held
by each of them. The 1,370,028 shares of Common Stock held by HW Investment are not reflected in Mr. Wahlström’s “Number
Registered for Sale Hereby” figure; they are reflected in the HW Investment row below. |
| (3) | The shares registered for resale hereby represent 67,817 shares of Common Stock. Mr. Cox also holds
(i) 18,879 shares of Common Stock issuable upon settlement of restricted stock units (2,063 of which can settle within 60 days),
and (ii) 118,204 shares of Common Stock issuable upon exercise of stock options (23,547 of which are exercisable within 60 days)
not registered for resale by this prospectus. Dr. Cox is our Chief Scientific and Manufacturing Officer. |
| (4) | Consists of 1,370,028 shares of Common Stock held directly by HW Investment. Messrs. Wahlström
and Hicks have shared voting and investment discretion with respect to the shares held directly by HW Investment and may be deemed to
have beneficial ownership of the shares held by each of them. |
| (5) | The shares registered for resale hereby represent 13,904 shares of Common Stock. Ms. Stevens also
holds (i) 18,879 shares of Common Stock issuable upon settlement of restricted stock units (2,063 of which can settle within 60 days),
and (ii) 160,032 shares of Common Stock issuable upon exercise of stock options (54,818 of which are exercisable within 60 days)
not registered for resale by this prospectus. Ms. Stevens is our Chief Regulatory Officer. |
| (6) | The shares registered for resale hereby represent 263,004 shares of Common Stock. Ms. Szela also
holds (i) 121,673 shares of Common Stock issuable upon settlement of restricted stock units (18,387 of which can settle within 60
days), and (ii) 1,088,182 shares of Common Stock issuable upon exercise of stock options (552,056 of which are exercisable within
60 days) not registered for resale by this prospectus. Ms. Szela is our Chief Executive Officer and a member of our board of directors. |
| (7) | The shares registered for resale hereby represent 8,372 shares of Common Stock. Mr. Marshak also
holds (i) 18,879 shares of Common Stock issuable upon settlement of restricted stock units (2,063 of which can settle within 60 days),
and (ii) 213,937 shares of Common Stock issuable upon exercise of stock options (71,554 of which are exercisable within 60 days)
not registered for resale by this prospectus. Mr. Marshak is our Senior Vice President, Corporate Development and Strategy. |
| (8) | The shares registered for resale hereby represent (i) 514,589 shares of Common Stock held directly
by Mr. Hicks, (ii) 1,370,028 shares of Common Stock held by HW Investment, (iii) 81,845 shares of Common Stock held by
the Millennium Trust Company, LLC, as custodian FBO Kerry Hicks IRAT and (iv) 322,737 shares of Common Stock held by The Kerry Raymond
Hicks Dynasty Trust, for which Mr. Hicks serves as trustee. In addition, the following shares beneficially owned by Mr. Hicks
are not registered for resale by this prospectus: 74,222 shares of Common Stock issuable upon exercise of stock options (30,371 of which
are exercisable within 60 days). Mr. Hicks has shared voting and investment discretion with respect to the shares held directly by
HW Investment and may be deemed to have beneficial ownership of the shares held by each of them. Mr. Hicks is a member of our board
of directors. The 1,370,028 shares of Common Stock held by HW Investment are not reflected in Mr. Hicks’ “Number Registered
for Sale Hereby” figure; they are reflected in the HW Investment row above. |
| (9) | The shares registered for resale hereby represent (i) 357,535 shares of Common Stock held by Murphy
Family Trust 2012 and (ii) 167,732 shares of Common Stock held by Sean E Murphy TTEE U/A 2/4/2004 (“Sean Murphy Trust”).
In addition, the following shares beneficially owned by Sean Murphy are not registered for resale by this prospectus: (i) 50,788
shares of Common Stock issuable upon settlement of restricted stock units (8,322 of which can settle within 60 days), and (ii) 464,681
shares of Common Stock issuable upon exercise of stock options (124,793 of which are exercisable within 60 days). Lisa Murphy, Mr. Murphy’s
spouse, has voting and investment discretion with respect to the shares held directly by Murphy Family Trust 2012 and thus Mr. Murphy
may be deemed to have beneficial ownership of the shares held directly by Murphy Family Trust 2012. Mr. Murphy is the trustee of
the Sean Murphy Trust and thus Mr. Murphy may be deemed to have beneficial ownership of the shares held directly by the Sean Murphy
Trust. Mr. Murphy is our Chief Financial Officer and a member of our board of directors. |
| (10) | The shares registered for resale hereby represent 17,799 shares of Common Stock. Dr. Katz also holds
(i) 50,788 shares of Common Stock issuable upon settlement of restricted stock units (8,322 of which can settle within 60 days),
and (iv) 445,127 shares of Common Stock issuable upon exercise of stock options (183,982 of which are exercisable within 60 days)
not registered for resale by this prospectus. Dr. Katz is our Chief Medical Officer. |
PLAN
OF DISTRIBUTION
We are registering the resale
by the Selling Securityholders or their permitted transferees from time to time of up to 10,587,582 shares of Common Stock issued
to Selling Securityholders pursuant to the Merger Agreement.
We are required to pay all
fees and expenses incident to the registration of the shares of Common Stock to be offered and sold pursuant to this prospectus, including
with regard to compliance with state securities or “blue sky” laws. The Selling Securityholders will bear all commissions
and discounts, if any, attributable to their sale of the shares of Common Stock.
We will not receive any of
the proceeds from the sale of the shares of Common Stock by the Selling Securityholders. The aggregate proceeds to the Selling Securityholders
will be the purchase price of the shares of Common Stock less any discounts and commissions borne by the Selling Securityholders.
The shares of Common Stock
beneficially owned by the Selling Securityholders covered by this prospectus may be offered and sold from time to time by the Selling
Securityholders. The term “Selling Securityholders” includes donees, pledgees, transferees or other successors in interest
selling shares of Common Stock received after the date of this prospectus from a Selling Securityholders as a gift, pledge, partnership
distribution or other transfer. The Selling Securityholders will act independently of us in making decisions with respect to the timing,
manner and size of each sale. Such sales may be made on one or more exchanges or in the over-the-counter market or otherwise. These sales
may be at fixed prices, at prevailing market prices at the time of sale, at prices related to the prevailing market price, at varying
prices determined at the time of sale, or at negotiated prices.
The Selling Securityholders
may sell their shares of Common Stock by one or more of, or a combination of, the following methods:
| · | purchases by a broker-dealer as principal and resale by such broker-dealer for its own account pursuant to this prospectus; |
| · | ordinary brokerage transactions and transactions in which the broker solicits purchasers; |
| · | block trades in which the broker-dealer so engaged will attempt to sell the shares as agent but may position and resell a portion
of the block as principal to facilitate the transaction; |
| · | an over-the-counter distribution in accordance with the rules of Nasdaq; |
| · | through trading plans entered into by a Selling Securityholder pursuant to Rule 10b5-1 under the Exchange Act, that are in place
at the time of an offering pursuant to this prospectus and any applicable prospectus supplement hereto that provide for periodic sales
of their shares of Common Stock on the basis of parameters described in such trading plans; |
| · | distribution to employees, members, limited partners or securityholders of the Selling Securityholders; |
| · | through the writing or settlement of options or other hedging transaction, whether through an options exchange or otherwise; |
| · | by pledge to secured debts and other obligations; |
| · | delayed delivery arrangements; |
| · | to or through underwriters or broker-dealers; |
| · | in “at the market” offerings, as defined in Rule 415 under the Securities Act, at negotiated prices, at prices prevailing
at the time of sale or at prices related to such prevailing market prices, including sales made directly on a national securities exchange
or sales made through a market maker other than on an exchange or other similar offerings through sales agents; |
| · | in privately negotiated transactions; |
| · | in options transactions; |
| · | through a combination of any of the above methods of sale; or |
| · | any other method permitted pursuant to applicable law. |
In addition, any shares of
Common Stock that qualify for sale pursuant to Rule 144 may be sold under Rule 144 rather than pursuant to this prospectus.
To the extent required, this
prospectus may be amended or supplemented from time to time to describe a specific plan of distribution. In connection with distributions
of the shares of Common Stock or otherwise, the Selling Securityholders may enter into hedging transactions with broker-dealers or other
financial institutions. In connection with such transactions, broker-dealers or other financial institutions may engage in short sales
of the shares of Common Stock in the course of hedging the positions they assume with selling securityholder. The Selling Securityholders
may also sell the shares of Common Stock short and redeliver the shares of Common Stock to close out such short positions. The Selling
Securityholders may also enter into option or other transactions with broker-dealers or other financial institutions which require the
delivery to such broker-dealer or other financial institution of shares of Common Stock offered by this prospectus, which shares of Common
Stock such broker-dealer or other financial institution may resell pursuant to this prospectus (as supplemented or amended to reflect
such transaction). The Selling Securityholder may also pledge shares of Common Stock to a broker-dealer or other financial institution,
and, upon a default, such broker-dealer or other financial institution, may effect sales of the pledged shares of Common Stock pursuant
to this prospectus (as supplemented or amended to reflect such transaction).
In effecting sales, broker-dealers
or agents engaged by the Selling Securityholder may arrange for other broker-dealers to participate. Broker-dealers or agents may receive
commissions, discounts or concessions from the Selling Securityholders in amounts to be negotiated immediately prior to the sale.
In connection with any
sales of shares of Common Stock offered hereunder, the Selling Securityholders and any underwriters, agents, brokers or dealers
participating in such sales will be deemed to be “underwriters” within the meaning of the Securities Act. Any profits
realized by any Selling Securityholder on the sales of shares of our Common Stock and any discounts, commissions or concessions received by the Selling Securityholders are deemed
to be underwriting discounts and commissions under the Securities Act. The compensation of any broker-dealer may also be deemed to be underwriting discounts and
under the Securities Act. Each Selling Securityholder will be subject to the prospectus delivery requirements of the Securities Act.
At the time a particular offer of shares of Common Stock is made, if required, a prospectus supplement will be distributed that will
set forth the number of shares of Common Stock being offered and the terms of the offering, including the name of any underwriter,
dealer or agent, the purchase price paid by any underwriter, any discount, commission and other item constituting compensation, any
discount, commission or concession allowed or reallowed or paid to any dealer, and the proposed selling price to the public.
In order to comply with the
securities laws of certain states, if applicable, the shares of Common Stock must be sold in such jurisdictions only through registered
or licensed brokers or dealers. In addition, in certain states the shares of Common Stock may not be sold unless they have been registered
or qualified for sale in the applicable state or an exemption from the registration or qualification requirement is available and is complied
with.
We have advised the Selling
Securityholders that the anti-manipulation rules of Regulation M under the Exchange Act may apply to sales of shares of Common Stock
in the market and to the activities of the Selling Securityholders and their affiliates. In addition, we will make copies of this prospectus
available to the Selling Securityholders for the purpose of satisfying the prospectus delivery requirements of the Securities Act. The
Selling Securityholders may indemnify any broker-dealer that participates in transactions involving the sale of the shares of Common Stock
against certain liabilities, including liabilities arising under the Securities Act.
We have agreed to indemnify
the Selling Securityholders against certain liabilities, including liabilities under the Securities Act and state securities laws, relating
to the registration of the shares offered by this prospectus.
Pursuant to the Amended
and Restated Registration Rights Agreement, we have agreed to keep the registration statement of which this prospectus constitutes a
part effective until such time as (A) the securities subject to such registration statement have been sold, transferred, disposed of
or exchanged in accordance with such registration statement; (B) such securities have been otherwise transferred, new
certificates or book entry provisions for such securities not bearing a legend restricting further transfer shall have been
delivered by the Company and subsequent public distribution of such securities shall not require registration under the Securities
Act; (C) such securities have ceased to be outstanding; (D) such securities may be sold without registration pursuant to
Rule 144 promulgated under the Securities Act (or any successor rule promulgated thereafter by the SEC) without limitation
as to volume and manner of sale or other public information requirements; or (E) such securities have been sold to, or through,
a broker, dealer or underwriter in a public distribution or other public securities transaction.
LEGAL
MATTERS
The validity of the shares
of Common Stock offered hereby will be passed upon for us by Cooley LLP.
EXPERTS
The consolidated financial statements of TriSalus Life Sciences, Inc. as of December 31, 2023 and 2022, and for the years then ended,
have been incorporated by reference herein in reliance upon the report of KPMG LLP, independent registered public accounting firm, incorporated
by reference herein, and upon the authority of said firm as experts in accounting and auditing.
WHERE
YOU CAN FIND MORE INFORMATION
We have filed with the SEC
a registration statement on Form S-3 under the Securities Act, with respect to the shares of Common Stock being offered by this prospectus.
This prospectus, which constitutes part of the registration statement, does not contain all of the information in the registration statement
and its exhibits. For further information with respect to us and the shares of Common Stock offered by this prospectus, we refer you to
the registration statement and its exhibits. Statements contained in this prospectus as to the contents of any contract or any other document
referred to are not necessarily complete, and in each instance, we refer you to the copy of the contract or other document filed as an
exhibit to the registration statement. Each of these statements is qualified in all respects by this reference. You can read our SEC filings,
including the registration statement, over the internet at the SEC’s website at www.sec.gov.
We are subject to the information
reporting requirements of the Exchange Act, and we file reports, proxy statements, and other information with the SEC. These reports,
proxy statements, and other information will be available for review at the SEC’s website at www.sec.gov. We also maintain a website
at www.trisaluslifesci.com. Through our website, we make available, free of charge, the documents that are filed with, or furnished to,
the SEC as soon as reasonably practicable after they are filed with, or furnished to, the SEC, including our Annual Reports on Form 10-K;
our proxy statements for our annual and special stockholder meetings; our Quarterly Reports on Form 10-Q; our Current Reports on
Form 8-K; Forms 3, 4, and 5 and Schedules 13D with respect to our securities filed on behalf of our directors and our executive
officers; and amendments to those documents. Unless incorporated by reference herein in the section titled "Incorporation of Certain
Information by Reference," the information contained on, or that may be accessed through, our website is not a part of, and is not
incorporated into, this prospectus.
INCORPORATION
OF CERTAIN INFORMATION BY REFERENCE
The SEC allows us to “incorporate
by reference” the information we file with it, which means that we can disclose important information to you by referring you to
those documents. The information incorporated by reference is considered to be part of this prospectus and information we file later with
the SEC will automatically update and supersede this information. Any statement contained in this prospectus or a previously filed document
incorporated by reference will be deemed to be modified or superseded for purposes of this prospectus to the extent that a statement contained
in this prospectus or a subsequently filed document incorporated by reference modifies or replaces that statement.
The documents we are incorporating
by reference as of their respective dates of filing are (other than Current Reports or portions thereof furnished under Item 2.02 or Item
7.01 of Form 8-K and exhibits filed on such form that are related to such items and other portions of documents that are furnished,
but not filed, or are otherwise not incorporated into registration statements pursuant to applicable rules promulgated by the SEC):
| · | our
Annual Report on Form 10-K for the year ended December 31, 2023, filed with the
SEC on April 11, 2024; |
| · | information
specifically incorporated by reference into our Annual Report on Form 10-K for the fiscal
year ended December 31, 2023 from our definitive proxy statement on Schedule 14A, filed
with the SEC on July 19, 2024; |
| · | our
Quarterly Reports on Form 10-Q for the quarters ended March 31, 2024 and June 30,
2024 filed with the SEC on May 15, 2024 and August 14, 2024, respectively; |
| · | our
Current Reports on Form 8-K filed with the SEC on January 25, 2024, March 12, 2024, April 16, 2024, April 30, 2024, May 7, 2024, May 24, 2024, June 27, 2024, July 1, 2024 and August 15, 2024; and |
| · | the
description of our securities contained in Exhibit 4.7 to our Quarterly Report on Form 10-Q
for the quarter ended June 30, 2024, filed with the SEC on August 14, 2024, together
with any amendment or report filed with the SEC for the purpose of updating such description. |
All documents we subsequently
file pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act, prior to the termination of this offering, including
all such documents we may file after the date of the initial registration statement of which this prospectus forms a part and prior to
the effectiveness of the registration statement, but excluding any information furnished to, rather than filed with, the SEC, will also
be incorporated by reference into this prospectus and deemed to be part of this prospectus from the date of the filing of such reports
and documents.
You may obtain any of the
documents incorporated by reference in this prospectus from the SEC through the SEC’s website at the address provided above. You
also may request a copy of any document incorporated by reference in this prospectus (excluding any exhibits to those documents, unless
the exhibit is specifically incorporated by reference in this document), at no cost, by writing or telephoning us at the following address
and phone number:
TriSalus Life Sciences, Inc.
6272 W. 91st Ave.,
Westminster, CO 80031
(888) 321-5212
PART II
INFORMATION NOT REQUIRED IN
PROSPECTUS
Item 14. Other Expenses of Issuance and Distribution.
The
following table sets forth all costs and expenses, other than underwriting discounts and commissions, payable by us in connection with
the sale of the shares of Common Stock being registered. All amounts shown are estimates except for
the SEC registration fee.
| |
Amount | |
SEC registration fee | |
$ | 6,613.51 | |
Accountants’ fees and expenses | |
$ | 25,000.00 | |
Legal fees and expenses | |
$ | 50,000.00 | |
Miscellaneous fees and expenses | |
$ | 15,000.00 | |
Total expenses | |
$ | 96,613.51 | |
Discounts, concessions, commissions
and similar selling expenses attributable to the sale of shares of Common Stock covered by this prospectus will be borne by the Selling Securityholders. We will pay all expenses (other than discounts, concessions, commissions and similar selling expenses) relating to the
registration of the shares with the SEC, as estimated in the table above.
Item 15. Indemnification of Directors and Officers.
Section 145 of the DGCL provides
that a corporation may indemnify directors and officers as well as other employees and individuals against expenses (including attorneys’
fees), judgments, fines and amounts paid in settlement actually and reasonably incurred by such person in connection with any threatened,
pending or completed actions, suits or proceedings in which such person is made a party by reason of such person being or having been
a director, officer, employee or agent of the Registrant. The DGCL provides that Section 145 is not exclusive of other rights to
which those seeking indemnification may be entitled under any bylaws, agreement, vote of stockholders or disinterested directors or otherwise.
The Registrant’s Certificate of Incorporation and Bylaws provide for indemnification by the Registrant of its directors and officers
to the fullest extent permitted by the DGCL.
Section 102(b)(7) of
the DGCL permits a corporation to provide in its Certificate of Incorporation that a director or officer of the corporation shall not
be personally liable to the corporation or its stockholders for monetary damages for breach of fiduciary duty as a director or officer,
except for liability (1) for any breach of the director’s or officer’s duty of loyalty to the corporation or its stockholders,
(2) for a director’s or officer’s acts or omissions not in good faith or which involve intentional misconduct or a knowing
violation of law, (3) for a director, unlawful payments of dividends or unlawful stock repurchases redemptions or other distributions,
(4) for a director or officer, any transaction from which the director or officer derived an improper personal benefit or (5) for
an officer, any action by or in the right of the corporation. The Registrant’s Certificate of Incorporation provides for such limitation
of liability to the fullest extent permitted by the DGCL.
The Registrant has entered into
indemnification agreements with each of its directors and executive officers to provide contractual indemnification in addition to the
indemnification provided in our Certificate of Incorporation. Each indemnification agreement provides for indemnification and advancements
by the Registrant of certain expenses and costs relating to claims, suits or proceedings arising from his or her service to the Registrant
or, at our request, service to other entities, as officers or directors to the maximum extent permitted by applicable law. We believe
that these provisions and agreements are necessary to attract qualified directors and officers.
The Registrant also maintains
standard policies of insurance under which coverage is provided (1) to its directors and officers against loss arising from claims
made by reason of breach of duty or other wrongful act, while acting in their capacity as directors and officers of the Registrant and
(2) to the Registrant with respect to payments which may be made by the Registrant to such officers and directors pursuant to any
indemnification provision contained in the Registrant’s Certificate of Incorporation and Bylaws or otherwise as a matter of law.
Item 16. Exhibits.
The exhibits listed below are
filed as part of this registration statement.
|
|
|
|
Incorporated by Reference |
Exhibit |
|
Description |
|
Schedule/
Form |
|
File Number |
|
Exhibits |
|
Filing Date |
2.1†** |
|
Agreement
and Plan of Merger, dated as of November 11, 2022, by and among MedTech Acquisition Corporation, MTAC Merger Sub, Inc.,
and TriSalus Life Sciences, Inc. |
|
Form 8-K |
|
001-39813 |
|
2.1 |
|
November 14,
2022 |
2.2** |
|
First
Amendment to Agreement and Plan of Merger, dated as of April 4, 2023, by and among MedTech Acquisition Corporation, MTAC Merger
Sub, Inc., and TriSalus Life Sciences, Inc. |
|
Form 8-K |
|
001-39813 |
|
10.1 |
|
April 5,
2023 |
2.3** |
|
Second
Amendment to Agreement and Plan of Merger, dated as of May 13, 2023, by and among MedTech Acquisition Corporation, MTAC Merger
Sub, Inc., and TriSalus Life Sciences, Inc. |
|
Form 8-K |
|
001-39813 |
|
10.1 |
|
May 15,
2023 |
2.4** |
|
Third
Amendment to Agreement and Plan of Merger, dated as of July 5, 2023, by and among MedTech Acquisition Corporation, MTAC Merger
Sub, Inc., and TriSalus Life Sciences, Inc. |
|
Form 8-K |
|
001-39813 |
|
10.1 |
|
July 6,
2023 |
4.1** |
|
Second
Amended and Restated Certificate of Incorporation of TriSalus Life Sciences, Inc. |
|
Form 8-K |
|
001-39813 |
|
3.1 |
|
August 16,
2023 |
4.2** |
|
Amended
and Restated Bylaws of TriSalus Life Sciences, Inc. |
|
Form 8-K |
|
001-39813 |
|
3.2 |
|
August 16,
2023 |
4.3** |
|
Form of
Certificate of Designations, Preferences and Rights of Series A Convertible Preferred Stock of TriSalus Life Sciences, Inc. |
|
Form 8-K |
|
001-39813 |
|
3.3 |
|
August 16,
2023 |
4.4** |
|
Specimen
Common Stock Certificate. |
|
Form 8-K |
|
001-39813 |
|
4.1 |
|
August 16,
2023 |
4.5** |
|
Specimen
Warrant Certificate. |
|
Form 8-K |
|
001-39813 |
|
4.2 |
|
August 16,
2023 |
4.6** |
|
Warrant
Agreement, dated December 17, 2020, by and between MTAC and Continental Stock Transfer & Trust Company. |
|
Form 8-K |
|
001-39813 |
|
4.1 |
|
December 23,
2020 |
4.7** |
|
Form of
Amended and Restated Registration Rights Agreement, by and among TriSalus Life Sciences, Inc., MedTech Acquisition Sponsor LLC,
and certain former stockholders of TriSalus Life Sciences, Inc. |
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Form 8-K |
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001-39813 |
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10.1 |
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November 14,
2022 |
4.8** |
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Registration
Rights Agreement, dated April 30, 2024, by and between TriSalus Life Sciences, Inc., and OrbiMed Royalty & Credit
Opportunities IV, LP. |
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Form 10-Q |
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001-39813 |
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4.4 |
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May 15,
2024 |
4.9** |
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Amendment
No. 1 to Warrant Agreement, dated June 26, 2024, by and between the Company and Continental Stock Transfer & Trust
Company. |
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Form 8-K |
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001-39813 |
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10.1 |
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June 27,
2024 |
4.10* |
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Substitute Warrant Certificate, August 15, 2024, by and between TriSalus Life Sciences, Inc., and OrbiMed Royalty & Credit Opportunities IV, LP. |
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4.11* |
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Substitute Warrant Certificate, dated August 15, 2024, by and between TriSalus Life Sciences, Inc., and OrbiMed Royalty & Credit Opportunities IV Offshore, LP. |
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5.1* |
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Opinion of Cooley LLP. |
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23.1* |
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Consent of KPMG LLP, independent registered public
accounting firm. |
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23.2* |
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Consent of Cooley LLP (included in Exhibit 5.1). |
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24.1* |
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Power of Attorney (included on signature page). |
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107* |
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Filing Fee Table. |
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| † | Certain of the exhibits and schedules to this Exhibit have been omitted in accordance with Regulation S-K Item 601(a)(5). The
Registrant agrees to furnish a copy of all omitted exhibits and schedules to the SEC upon its request; provided, however, that the Registrant
may request confidential treatment pursuant to Rule 24b-2 of the Exchange Act, as amended, for any schedule or exhibit so furnished. |
Item 17. Undertakings.
| (a) | The undersigned registrant hereby undertakes as follows: |
| (1) | To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement: |
| (i) | To include any prospectus required by Section 10(a)(3) of the Securities Act of 1933; |
| (ii) | To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth
in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar
value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum
offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate,
the changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in the “Calculation
of Registration Fee” table in the effective registration statement; and |
| (iii) | To include any material information with respect to the plan of distribution not previously disclosed in the registration statement
or any material change to such information in the registration statement; |
provided, however, that: Paragraphs (a)(1)(i),
(a)(1)(ii) and (a)(1)(iii) of this section do not apply if the registration statement is on Form S-3 and the information
required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Commission
by the registrant pursuant to Section 13 or Section 15(d) of the Exchange Act, that are incorporated by reference in the
registration statement, or is contained in a form of prospectus filed pursuant to Rule 424(b) that is part of the registration
statement.
| (2) | That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be deemed
to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall
be deemed to be the initial bona fide offering thereof. |
| (3) | To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the
termination of the offering. |
| (4) | That, for the purpose of determining liability under the Securities Act of 1933 to any purchaser: |
| (i) | Each prospectus filed by the registrant pursuant to Rule 424(b)(3) shall be deemed to be part of the registration statement
as of the date the filed prospectus was deemed part of and included in the registration statement; and |
| (ii) | Each prospectus required to be filed pursuant to Rule 424(b)(2), (b)(5) or (b)(7) as part of a registration statement
in reliance on Rule 430B relating to an offering made pursuant to Rule 415(a)(1)(i), (vii) or (x) for the purpose
of providing the information required by Section 10(a) of the Securities Act shall be deemed to be part of and included in the
registration statement as of the earlier of the date such form of prospectus is first used after effectiveness or the date of the first
contract of sale of securities in the offering described in the prospectus. As provided in Rule 430B, for liability purposes of the
issuer and any person that is at that date an underwriter, such date shall be deemed to be a new effective date of the registration statement
relating to the securities in the registration statement to which that prospectus relates, and the offering of such securities at that
time shall be deemed to be the initial bona fide offering thereof. Provided, however, that no statement made in a registration statement
or prospectus that is part of the registration statement or made in a document incorporated or deemed incorporated by reference into the
registration statement or prospectus that is part of the registration statement will, as to a purchaser with a time of contract of sale
prior to such effective date, supersede or modify any statement that was made in the registration statement or prospectus that was part
of the registration statement or made in any such document immediately prior to such effective date |
| (b) | That, for the purpose of determining liability of the registrant
under the Securities Act each filing of the Registrant’s annual report pursuant to Section 13(a) or 15(d) of
the Exchange Act (and, where applicable, each filing of an employee benefit plan’s annual report pursuant to Section 15(d) of
the Exchange Act) that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating
to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering
thereof. |
| (c) | Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and controlling
persons of the undersigned pursuant to the foregoing provisions, or otherwise, the undersigned has been advised that in the opinion of
the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event
that a claim for indemnification against such liabilities (other than the payment by the undersigned of expenses incurred or paid by a
director, officer or controlling person of the undersigned in the successful defense of any action, suit or proceeding) is asserted by
such director, officer or controlling person in connection with the securities being registered, the undersigned will, unless in the opinion
of our counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the Act and will be governed by the final adjudication of such issue. |
SIGNATURES
Pursuant
to the requirements of the Securities Act of 1933, the Company has duly caused this registration statement on Form S-3 to
be signed on its behalf by the undersigned, thereunto duly authorized in the City of Westminster, State of Colorado, on this 29th day
of October, 2024.
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TRISALUS LIFE SCIENCES, INC. |
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By: |
/s/ Mary Szela |
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Mary Szela |
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Chief Executive Officer |
POWER OF ATTORNEY
KNOW ALL
PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Mary Szela and Sean Murphy, and each
one of them, as his or her true and lawful attorneys-in-fact and agents, with full power to act alone, with full powers of substitution
and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments
(including post-effective amendments) to this registration statement on Form S-3, and to sign any registration statement for the
same offering covered by this registration statement that is to be effective on filing pursuant to Rule 462(b) under the Securities
Act of 1933, as amended, and all post-effective amendments thereto, and to file the same, with all exhibits thereto and other documents
in connection therewith, with the SEC, granting unto said attorneys-in-fact and agents, and each one of them, full power and authority
to do and perform each and every act and thing requisite and necessary to be done in connection therewith,as fully for all intents and
purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or any
of them, or her substitute or resubstitute, may lawfully do or cause to be done by virtue hereof.
Pursuant
to the requirements of the Securities Act of 1933, this registration statement on Form S-3 has been signed by the following persons
in the capacities and on the dates indicated.
/s/ Mary Szela |
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Chief Executive Officer and Director |
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October 29, 2024 |
Mary Szela |
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(Principal Executive Officer) |
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/s/ Sean Murphy |
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Chief Financial Officer and Director |
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October 29, 2024 |
Sean Murphy |
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(Principal Financial and Accounting Officer) |
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/s/ Mats Wahlström |
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Chairman |
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October 29, 2024 |
Mats Wahlström |
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/s/ Arjun “JJ” Desai |
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Director |
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October 29, 2024 |
Arjun “JJ” Desai |
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/s/ Andrew von Eschenbach |
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Director |
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October 29, 2024 |
Andrew von Eschenbach |
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/s/ Kerry Hicks |
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Director |
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October 29, 2024 |
Kerry Hicks |
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/s/ Liselotte Hyveled |
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Director |
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October 29, 2024 |
Liselotte Hyveled |
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/s/ George Kelly Martin |
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Director |
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October 29, 2024 |
George Kelly Martin |
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/s/ David J. Matlin |
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Director |
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October 29, 2024 |
David J. Matlin |
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/s/ Anil Singhal |
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Director |
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October 29, 2024 |
Anil Singhal |
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Exhibit 4.10
Execution Version
WARRANT CERTIFICATE
THIS WARRANT CERTIFICATE AND
THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED
(THE “SECURITIES ACT”), OR QUALIFIED UNDER ANY STATE OR FOREIGN SECURITIES LAWS AND MAY NOT BE OFFERED FOR SALE, SOLD,
PLEDGED, HYPOTHECATED OR OTHERWISE TRANSFERRED OR ASSIGNED UNLESS (I) A REGISTRATION STATEMENT COVERING THE OFFER AND SALE OF SUCH
SECURITIES IS EFFECTIVE UNDER THE SECURITIES ACT AND IS QUALIFIED UNDER APPLICABLE STATE AND FOREIGN LAW OR (II) THE TRANSACTION
IS EXEMPT FROM THE REGISTRATION AND PROSPECTUS DELIVERY REQUIREMENTS UNDER THE SECURITIES ACT AND THE QUALIFICATION REQUIREMENTS UNDER
APPLICABLE STATE AND FOREIGN LAW AND, IN EACH CASE, IF THE COMPANY REQUESTS, AN OPINION SATISFACTORY TO THE COMPANY TO SUCH
EFFECT HAS BEEN RENDERED BY COUNSEL.
Warrant Shares Issuable: | 92,801
Common Shares |
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Issue Date: | August 15,
2024 (Substitute Warrant Certificate #1 to Initial Certificate April 30, 2024) |
FOR VALUE RECEIVED, TRISALUS
LIFE SCIENCES, INC., a Delaware corporation (the “Company”), hereby certifies that ORBIMED ROYALTY &
CREDIT OPPORTUNITIES IV, LP, a Delaware limited partnership (the “Initial Holder” and, together with its successors
and permitted transferees and assigns, a “Holder”) is entitled to purchase, at the per share Exercise Price,
up to Ninety-Two Thousand Eight Hundred and One (92,801) fully paid and nonassessable Common Shares (as subject to adjustment hereunder,
the “Warrant Shares”), all subject to the terms, conditions and adjustments set forth below in this Warrant
Certificate. Certain capitalized terms used herein are defined in Section 1.
This Warrant Certificate is
being issued as a Substitute Warrant Certificate as defined in and pursuant to the Assignment dated August 15, 2024, by and between
OrbiMed Royalty & Credit Opportunities IV Offshore, LP and Initial Holder with respect to the Warrant Certificate issued April 30,
2024 (the “Initial Certificate”). The Initial Certificate was issued as a condition precedent to the making
of loans under and pursuant to the Credit Agreement, dated as of April 30, 2024 (as amended or otherwise modified from time to time,
the “Credit Agreement”), among TriSalus Operating Life Sciences, Inc., as borrower, the Company, the lenders
party thereto, and OrbiMed Royalty & Credit Opportunities IV, LP, as the administrative agent.
Section 1. Definitions.
Capitalized terms used in this Warrant Certificate but not defined herein have the meanings ascribed thereto in the Credit Agreement as
in effect on the date hereof. The following terms when used herein have the following meanings:
“Aggregate Exercise
Price” means, with respect to any exercise of this Warrant Certificate for Warrant Shares, an amount equal to the product
of (i) the number of Warrant Shares in respect of which this Warrant Certificate is then being exercised pursuant to Section 3,
multiplied by (ii) the Exercise Price.
“Bloomberg”
has the meaning set forth within the definition of “VWAP”.
“Cashless Exercise”
has the meaning set forth in Section 3(b).
“Charter”
means the Second Amended and Restated Certificate of Incorporation of the Company, as amended as of August 10, 2023.
“Common Shares”
means the Company’s common stock, par value $0.0001 per share.
“Common Shares
Deemed Outstanding” means, at any given time, the sum of (i) the number of Common Shares actually outstanding at such
time, plus (ii) the number of Common Shares issuable upon exercise of Options actually outstanding at such time, plus (iii) the
number of Common Shares issuable upon conversion or exchange of Convertible Securities actually outstanding at such time (treating as
actually outstanding any Convertible Securities issuable upon exercise of Options actually outstanding at such time), in each case, regardless
of whether the Options or Convertible Securities are actually exercisable at such time; provided that Common Shares Deemed Outstanding
at any given time shall not include shares owned or held by or for the account of the Company or any or its wholly owned subsidiaries.
“Company”
has the meaning set forth in the preamble.
“Convertible Securities”
means any Capital Securities that, directly or indirectly, are convertible into, exchangeable or settleable for Common Shares, including
shares of the Company’s preferred stock that may be issued from time to time.
“Credit Agreement”
has the meaning set forth in the preamble.
“Determination
Date” has the meaning set forth in the definition of “VWAP”.
“Exchange Act”
means the Securities Exchange Act of 1934, as amended.
“Exercise Certificate”
has the meaning set forth in Section 3(a)(i).
“Exercise Date”
means, for any given exercise of this Warrant Certificate, whether in whole or in part, a Business Day on which the conditions to such
exercise as set forth in Section 3 shall have been satisfied at or prior to 5:00 p.m., New York City time, including, without
limitation, the receipt by the Company of the Exercise Certificate.
“Exercise Period”
means the period from (and including) the Issue Date to (and including) 5:00 p.m., New York City time, on the Expiration Date.
“Exercise Price”
means $9.5562, as adjusted from time to time pursuant to Section 4.
“Expiration Date”
means April 30, 2031.
“Fair Market Value”
means (i) if the Common Shares are traded on a Trading Market, the VWAP of such Common Shares for such day (provided that if the
Fair Market Value is being determined in connection with a Sale of the Company, such Fair Market Value shall be the greater of the amount
determined pursuant to this clause (i) and the closing price on the Trading Market on the Trading Day immediately prior to the closing
date of the Sale of the Company) or (ii) if at any time the Common Shares are not listed, quoted or otherwise available for trading
on any Trading Market (so that no Trading Day shall have occurred), or if VWAP cannot be calculated for the Common Shares for such day
for any other reason, the “Fair Market Value” of such Common Shares shall be the fair market value per share
of such Common Shares as determined jointly by the Company and the Holder; provided further, that, in the event the Company and
Holder are unable to so mutually agree, Fair Market Value shall be determined pursuant to Section 10(a).
“Holder”
has the meaning set forth in the preamble.
“Independent Advisor”
has the meaning set forth in Section 10(a).
“Initial Holder”
has the meaning set forth in the preamble.
“Issue Date”
means the date designated as such on the first page of this Warrant Certificate.
“Marketable Securities”
means equity securities meeting each of the following requirements: (i) the issuer thereof is subject to the reporting requirements
of Section 13 or Section 15(d) of the Exchange Act, and is current in its filing of all required reports and other information
under the Securities Act and the Exchange Act; (ii) such equity securities are traded on a Trading Market; and (iii) if delivered
(or to be delivered) as payment or compensation to the Holder in connection with an automatic Cashless Exercise pursuant to Section 3(c),
following the closing of the related Sale of the Company, the Holder would not be restricted from publicly re-selling all of such equity
securities delivered to it.
“Nasdaq”
means The Nasdaq Stock Market LLC.
“NYSE”
means the New York Stock Exchange.
“Options”
means any warrants, options or similar rights to subscribe for or purchase Common Shares or Convertible Securities.
“Original Issue
Date” means April 30, 2024.
“OTC Bulletin
Board” means the Financial Industry Regulatory Authority, Inc. OTC Bulletin Board.
“Pre-emptive Rights”
has the meaning set forth in Section 12.
“Registration
Statement” means, in connection with any public offering of securities, any registration statement required pursuant to
the Securities Act that covers the offer and sales of any such securities, including any prospectus, amendments or supplements to such
Registration Statement, including post-effective amendments and all exhibits and all materials incorporated by reference in such Registration
Statement.
“Rule 144”
means Rule 144 promulgated under the Securities Act.
“Sale of the Company”
means a transaction pursuant to which (i) (x) any Person or group of Persons acting jointly or otherwise in concert (other than
the Holder and any other parties to the Credit Agreement) acquires ownership, directly or indirectly, beneficially or of record, of Capital
Securities of the Company having more than fifty percent (50%) of the aggregate economic interests and/or voting power, determined on
a fully diluted basis, (y) any Person or group of Persons acting jointly or otherwise in concert (other than the Holder and any other
parties to the Credit Agreement) acquires, by contract or otherwise, the right to appoint or elect a majority of the Company’s board
of directors (the “Board”), or (z) all or substantially all of the assets of the Company and its Subsidiaries,
taken as a whole, are sold, leased, exclusively licensed, transferred, conveyed or otherwise disposed of, and (ii) all Obligations
outstanding under the Credit Agreement are to be paid in full in cash, whether pursuant to the terms of the transaction, pursuant to the
terms of the Credit Agreement or otherwise.
“SEC”
means the Securities and Exchange Commission or any successor thereto.
“Share Distribution”
means any issuance or sale by the Company of any of its Common Shares, Options or Convertible Securities, other than in connection with
a dividend or distribution to holders of its Common Shares of the type described in Section 4(c) below.
“Share Reorganization”
has the meaning set forth in Section 4(a).
“Trading Day”
means, with respect to the Common Shares or any other Marketable Securities, a date on which the relevant Trading Market is open and conducting
business.
“Trading Market”
means, with respect to the Common Shares or any other Marketable Securities, the Nasdaq, the NYSE or the OTC Bulletin Board.
“Unrestricted
Conditions” has the meaning set forth in Section 11(a)(ii).
“VWAP”
means, with respect to any Common Shares, as of any day of determination (a “Determination Date”), the volume
weighted average sale price for the period of ten (10) consecutive Trading Days immediately preceding such Determination Date on
the Trading Market for such Common Shares as reported by, or based upon data reported by, Bloomberg Financial Markets or an equivalent,
reliable reporting service reasonably acceptable to the Holder and the Company (collectively, “Bloomberg”) or,
if the volume weighted average sale price has not been reported for such security by Bloomberg for such ten (10) day period, then
the simple average of the last closing trade prices of such security for such ten (10) day period, as reported by Bloomberg, or,
if no last closing trade price is reported for such security by Bloomberg, the simple average of the bid prices of any market makers for
such security that are listed in the over the counter market by the Financial Industry Regulatory Authority, Inc. or on the OTC Bulletin
Board (or any successor) or in the “pink sheets” (or any successor) by the OTC Markets Group, Inc. over such ten (10) day
period.
“Warrant Certificate”
means this Warrant Certificate and all subsequent warrant certificates issued upon division, combination or transfer of, or in substitution
for, this Warrant Certificate.
“Warrant Register”
has the meaning set forth in Section 5.
“Warrant Shares”
has the meaning set forth in the preamble.
Section 2.
Term of Warrant Certificate. Subject to the terms and conditions hereof, from time to time during
the Exercise Period, the Holder of this Warrant Certificate may exercise this Warrant Certificate for all or any part of the Warrant
Shares purchasable hereunder (subject to adjustment as provided herein).
Section 3.
Exercise of Warrant Certificate.
(a) Exercise
Procedure. This Warrant Certificate may be exercised from time to time on any Business Day during the Exercise Period, for all or
any part of the unexercised Warrant Shares, upon:
(i) delivery
to the Company at its then registered office of a duly completed and executed Exercise Certificate in the form attached hereto as Exhibit A
(each, an “Exercise Certificate”), which certificate will specify the number of Warrant Shares to be purchased
and the Aggregate Exercise Price; and
(ii) simultaneously
with the delivery of the Exercise Certificate, payment to the Company of the Aggregate Exercise Price in accordance with Section 3(b).
(b) Payment
of the Aggregate Exercise Price. Payment of the Aggregate Exercise Price shall be made, at the option of the Holder as set forth in
the applicable Exercise Certificate, by any of the following methods:
(i) by
wire transfer of immediately available funds to an account designated in writing by the Company, in the amount of such Aggregate Exercise
Price;
(ii) by
instructing the Company to withhold a number of Warrant Shares then issuable upon exercise of this Warrant Certificate with an aggregate
Fair Market Value as of the Exercise Date equal to such Aggregate Exercise Price; or
(iii) any
combination of the foregoing.
In the event of any withholding of Warrant Shares
pursuant to Section 3(b)(ii) or (iii) (solely to the extent of such withholding, a “Cashless
Exercise”) where the number of shares whose value is equal to the Aggregate Exercise Price is not a whole number, the number
of shares withheld by the Company shall be rounded up to the nearest whole share and the Company shall make a cash payment to the Holder
(by delivery of a certified or official bank check or by wire transfer of immediately available funds) based on the incremental fraction
of a share being so withheld by the Company in an amount equal to the product of (x) such incremental fraction of a share being so
withheld multiplied by (y) the Fair Market Value per Warrant Share as of the Exercise Date.
(c) Automatic
Cashless Exercise. To the extent this Warrant Certificate has not been exercised in full by the Holder prior to the earlier of (i) the
occurrence of the Expiration Date, and (ii) the date on which a Sale of the Company is consummated pursuant to which the sole consideration
payable to the Company or its shareholders in respect of such sale transaction consists of cash, Marketable Securities or a combination
thereof, any portion of this Warrant Certificate that remains unexercised on such date shall be deemed to have been exercised automatically
pursuant to a Cashless Exercise, in whole (and not in part), on the Business Day immediately preceding such date; provided, that
the automatic Cashless Exercise contemplated by this Section 3(c) shall not occur in the event that, as of the Business
Day immediately preceding any such date described above, the per share Fair Market Value of a Warrant Share is less than the Exercise
Price per Warrant Share, in which case, this Warrant Certificate shall automatically expire and be of no further force and effect as of
the Expiration Date or immediately prior to the consummation of the Sale of the Company, as applicable.
To the extent permitted by applicable Law, for
purposes of Rule 144, (i) the Warrant Shares issuable upon any exercise of this Warrant Certificate in any Cashless Exercise
transaction shall be deemed to have been acquired on the Original Issue Date, and (ii) the holding period for any Warrant Shares
issuable upon the exercise of this Warrant Certificate in any Cashless Exercise transaction shall be deemed to have commenced on the Original
Issue Date; provided that the Company makes no representation or warranty regarding the commencement of the holding period of any
Warrant Share.
(d) Delivery
of Stock Certificates. With respect to any exercise of this Warrant Certificate by the Holder, upon receipt by the Company of an Exercise
Certificate and delivery of the Aggregate Exercise Price, the Company shall, within five (5) Business Days, deliver in accordance
with the terms hereof to or upon the order of the Holder that number of Warrant Shares for the portion of this Warrant Certificate so
exercised on such date, together with cash in lieu of any fraction of a share to the extent the Company elects to do so pursuant to Section 3(e) below.
If such Warrant Shares are issued in certificated form, the Company shall deliver a certificate or certificates, to the extent possible,
representing the number of Warrant Shares as the Holder shall request in the Exercise Certificate. If such Warrant Shares are issued in
uncertificated form, the Company shall deliver upon request a confirmation evidencing the registration of such shares. Unless otherwise
provided herein, upon any exercise in accordance with the terms of this Warrant Certificate, this Warrant Certificate shall be deemed
to have been exercised and such certificate or certificates of Warrant Shares shall be deemed to have been issued, and the Holder shall
be deemed to have become a holder of record of such Warrant Shares for all purposes, as of the Exercise Date. Unless otherwise permitted
by federal or state securities laws, rules or regulations, any share certificates issued pursuant to the exercise of this Warrant
Certificate will bear a legend in substantially the form set out in Section 11(a)(i) below.
(e) No
Fractional Shares or Scrip. No fractional or scrip representing fractional shares shall be issued upon the exercise of this Warrant
Certificate. As to any fraction of a share which the Holder would otherwise be entitled to purchase upon such exercise, the Company shall
at its election, either pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied by the
Fair Market Value of one Warrant Share on the Exercise Date or round up to the next whole share.
(f) Surrender
of this Warrant Certificate; Delivery of New Warrant Certificate.
(i) The
Holder shall not be required to physically surrender this Warrant Certificate to the Company until this Warrant Certificate has been exercised
in full by the Holder, in which case, the Holder shall, at the written request of the Company, surrender this Warrant Certificate to the
Company for cancellation within three (3) Business Days after the date the final Exercise Certificate is delivered to the Company.
Partial exercises of this Warrant Certificate resulting in purchases of a portion of the total number of Warrant Shares available hereunder
shall have the effect of lowering the outstanding number of Warrant Shares issuable hereunder by an amount equal to the applicable number
of Warrant Shares that have been issued hereunder as a result of previous exercises or withheld in connection with any Cashless Exercises.
The Holder and the Company shall maintain records showing the number of Warrant Shares issued and purchased, the date of such issuances
and purchases and the number of Warrant Shares withheld in connection with any Cashless Exercises. The Holder and any assignee, by acceptance
of this Warrant Certificate, acknowledge and agree that, by reason of the provisions of this Section 3(f), following the purchase
of a portion of the Warrant Shares hereunder, the number of Warrant Shares available for purchase hereunder at any given time may be fewer
than the amount stated on the face hereof.
(ii) Notwithstanding
the foregoing, to the extent that there are unexpired and unexercised Warrant Shares remaining under the Warrant Certificate, the Holder
may request that the Company (and the Company shall), at the time of issuance of any Warrant Shares in accordance with Section 3(d) and
the surrender of this Warrant Certificate, deliver to the Holder a new Warrant Certificate evidencing the rights of the Holder to subscribe
for the unexpired and unexercised Warrant Shares called for by this Warrant Certificate. Unless otherwise agreed upon by the Holder in
its sole discretion, such new Warrant Certificate shall in all other respects be identical to this Warrant Certificate.
(g) Valid
Issuance of Warrant Certificate and Warrant Shares; Payment of Taxes. With respect to the exercise of this Warrant Certificate, the
Company hereby represents, warrants, covenants and agrees as follows:
(i) This
Warrant Certificate is, and any Warrant Certificate issued in substitution for or replacement of this Warrant Certificate shall be, upon
issuance, duly authorized.
(ii) All
Warrant Shares issuable upon the exercise of this Warrant Certificate (or any substitute or replacement Warrant Certificate) shall be,
upon issuance, and the Company shall take all such actions as may be necessary or appropriate in order that such Warrant Shares are, validly
issued, fully paid and non-assessable, issued without violation of any preemptive or similar rights of any shareholder of the Company
and free and clear of all liens and charges (other than liens or charges created by the Holder, or created with regard to income taxes
or other taxes payable by the Holder incurred in connection with the exercise of the Warrant or taxes in respect of any transfer made
by the Holder occurring contemporaneously therewith).
(iii) The
Company shall take all such actions as may be necessary to (x) comply with Section 3(i) below and (y) ensure
that all such Warrant Shares are issued without violation by the Company of any applicable Law or any requirements of any foreign or domestic
securities exchange upon which Warrant Shares may be listed at the time of such exercise.
(iv) The
Company shall exclusively bear and pay all expenses in connection with, and all governmental charges, taxes, fees, levies, withholdings
and all other such payments, that may be imposed on or with respect to, the issuance of this Warrant Certificate, and the issuance or
delivery of Warrant Shares pursuant to the terms of this Warrant Certificate and the Holder shall not be affected by such payments, and
the Company shall not be eligible to any indemnification for such payment from the Holder.
(v) The
Company is a corporation duly organized and validly existing under the Laws of the State of Delaware and has the capacity and corporate
power and authority to enter into this Warrant Certificate.
(vi) The
Company has taken all action required to be taken to authorize the execution, delivery and performance of this Warrant Certificate.
(vii) This
Warrant Certificate has been duly executed by the Company.
(viii) The
obligations of the Company under this Warrant Certificate are legal, valid and binding obligations, enforceable against the Company in
accordance with the terms hereof, except to the extent that enforceability may be limited by bankruptcy, insolvency, reorganization, moratorium
or similar laws affecting creditors’ rights generally and by general equitable principles.
(ix) As
of the Issue Date, the Company has complied with all obligations set forth in Section 3(i), below.
(h)
Conditional Exercise. Notwithstanding any other provision hereof, if an exercise of all or any portion
of this Warrant Certificate is to be made in connection with a Sale of the Company, such exercise may, at the election of the
Holder, be conditioned upon the consummation of such transaction, in which case such exercise shall not be deemed to be effective
until immediately prior to the consummation of such transaction.
(i) Reservation
of Shares. The Company shall at all times during the Exercise Period reserve and keep available out of its authorized but unissued
Common Shares or (if applicable) other securities constituting Warrant Shares, solely for the purpose of issuance upon the exercise of
this Warrant Certificate, the maximum number of Warrant Shares issuable upon the exercise of this Warrant Certificate. The Company shall
not increase the par value of any Warrant Shares receivable upon the exercise of this Warrant Certificate above the Exercise Price then
in effect, and shall take all such actions within its power as may be necessary or appropriate in order that the Company may validly and
legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant Certificate.
(j) Rule 144
Compliance. With a view to making available to the Holder the benefits of Rule 144 and any other rule or regulation of the
SEC that may at any time permit a holder to sell securities of the Company to the public without registration or pursuant to a Registration
Statement, the Company shall, during the Exercise Period while any portion of this Warrant Certificate remains unexercised:
(i) use
commercially reasonable efforts to make and keep adequate public information available, as required by clause (c) of Rule 144;
(ii) use
commercially reasonable efforts to file with the SEC in a timely manner all reports and other documents required of the Company under
the Securities Act and the Exchange Act (excluding, for avoidance of doubt, any prospectus or registration statement which the Company
is under no obligation to file); and
(iii) furnish,
or otherwise make available to the Holder so long as the Holder owns Warrant Shares, promptly upon request, a written statement by the
Company as to its compliance with the reporting requirements of Rule 144 and the Exchange Act, a copy of the most recent annual or
quarterly report of the Company, and such other reports and documents so filed or furnished by the Company with the SEC under the Exchange
Act or Securities Act as the Holder may reasonably request in connection with the sale of Common Shares without registration.
(k) Ownership
Cap. The Company shall not knowingly effect the exercise of this Warrant Certificate, and the Holder shall not have the right to exercise
this Warrant Certificate to the extent that, after giving effect to such exercise, the Holder (together with its Affiliates) would beneficially
own in excess of 9.99% of the Common Shares of the Company immediately after giving effect to such exercise. For purposes of the foregoing
sentence, the aggregate number of Common Shares owned by the Holder and its Affiliates shall include the number of Warrant Shares issuable
upon exercise of this Warrant Certificate with respect to which the determination of such aggregate number is being made, but shall exclude
Common Shares (if any) that would be issuable upon (i) exercise of the remaining, unexercised portion of this Warrant Certificate
beneficially owned by the Holder and its Affiliates and (ii) exercise or conversion of the unexercised or unconverted portion of
any other Capital Securities of the Company beneficially owned by the Holder and its Affiliates (including, without limitation, any Convertible
Securities) subject to a limitation on conversion or exercise analogous to the limitations contained herein. Except as set forth in the
preceding sentence, for purposes of this Section 3(k), beneficial ownership shall be calculated in accordance with Section 13(d) of
the Exchange Act. For purposes of this Warrant Certificate, in determining the number of outstanding Common Shares, the Holder of this
Warrant Certificate may rely on the number of such outstanding Capital Securities as reflected in the most recent of (i) the Company’s
Form 10-K, Form 10-Q or other public filing with the SEC, as the case may be, if available, (ii) a more recent public announcement
by the Company, or (iii) any other notice by the Company or its transfer agent setting forth the number of outstanding Common Shares.
In addition, upon the written request of the Holder (but not more than once during any calendar quarter), the Company shall, within three
(3) Business Days, confirm to the Holder the number of its outstanding Common Shares. Furthermore, upon the written request of the
Company (but not more than once during any calendar quarter), the Holder shall promptly confirm to the Company its then current beneficial
ownership with respect to the Company’s Common Shares.
(l) Except
as expressly provided herein with respect to cash payments in lieu of the issuance of fractional shares, and without regard to any exchange
of consideration in connection with an automatic Cashless Exercise pursuant to Section 3(c) above or similar event, upon
exercise of this Warrant Certificate the Holder shall not otherwise be entitled to receive cash or Warrant Shares that are registered
under the Securities Act.
Section 4. Adjustment
to Number of Warrant Shares, Exercise Price, etc. The number of Warrant Shares issuable upon exercise of this Warrant Certificate
shall be subject to adjustment from time to time as provided in this Section 4.
(a) Adjustment
to Number of Warrant Shares Upon Reorganizations, Reclassifications, etc. In the event of any changes in the outstanding Common
Shares of the Company by reason of redemptions, recapitalizations, reclassifications, combinations or exchanges of shares, splits or reverse
splits, separations, reorganizations, liquidations, substitutions, replacements or the like (any of the foregoing or combination thereof
being a “Share Reorganization”), the number and class of Warrant Shares available upon exercise of this Warrant
Certificate in the aggregate and the Exercise Price shall be correspondingly adjusted to give the Holder of this Warrant Certificate,
on exercise for the same Aggregate Exercise Price, the total number, class, and kind of shares as the Holder would have owned had this
Warrant Certificate been exercised prior to any such event and had the Holder continued to hold such Warrant Shares until after the event
requiring adjustment. The form of this Warrant Certificate need not be changed because of any adjustment in the number of Warrant Shares
subject to this Warrant Certificate.
(b) Adjustment
to Exercise Price Upon a Share Distribution. Subject to clause (iii) below, if the Company consummates or effects
any Share Distribution for a price per Common Share less than the Exercise Price then in effect, then, effective upon such Share Distribution,
the Exercise Price shall be reduced to a price determined by multiplying the Exercise Price then in effect by a fraction, the numerator
of which shall be the sum of (A) the number of Common Shares Deemed Outstanding immediately prior to such Share Distribution multiplied
by the Exercise Price then in effect, plus (B) the consideration, if any, received by the Company upon such Share Distribution, and
the denominator of which shall be the product of (1) the total number of Common Shares Deemed Outstanding immediately after such
Share Distribution multiplied by (2) the Exercise Price in effect immediately prior to such Share Distribution. For purposes of this
Section 4(b):
(i) In
the event Options or Convertible Securities are included in any such Share Distribution, the price per Common Share deemed to have been
issued or sold as a result of the sale or issuance of such Options or Convertible Securities, shall be equal to the price per Common Share
for which Common Shares are issuable upon the exercise of such Options or upon conversion or exchange of such Convertible Securities,
as the case may be (determined by dividing (x) the aggregate amount, if any, received or receivable by the Company as consideration
for the issuance, sale, distribution or grant of all such Options or Convertible Securities, plus the minimum aggregate amount of additional
consideration payable to the Company, if any, upon the exercise of all such Options or the conversion or exchange of all such Convertible
Securities (as the case may be), by (y) the total maximum number of Common Shares issuable upon the exercise of all such Options
or upon the conversion or exchange of all such Convertible Securities (without, in each case, giving effect to any anti-dilution provisions
included in such Options or Convertible Securities that are not applicable at the time of the applicable price per Common Share calculations)).
(ii) The
provisions of this Section 4(b) shall not in any event operate to increase the Exercise Price.
(iii) This
Section 4(b) shall not apply to any of the following:
| (A) | Any issuance, sale or other distribution of Common Shares, Options or Convertible Securities pursuant
to (i) any Share Reorganization, which shall instead be governed by Section 4(a) above, or (ii) any dividend
or distribution to holders of Common Shares, which shall instead by governed by Section 4(c) below. |
| (B) | The issuance of Common Shares upon exercise or conversion of any Options or Convertible Securities included
in the Common Shares Deemed Outstanding as of the Original Issue Date. |
| (C) | The grant or issuance of Common Shares, Options or Convertible Securities to board members, officers,
employees, consultants or other service providers of the Company pursuant to any employee incentive plan, employee share purchase plan
or similar equity-based benefit plans (including any inducement award granted in accordance with the Nasdaq Listing Rules) approved by
the Company’s Board or duly authorized committee thereof; provided that the total number of securities issued under this
sub-clause for a price per share less than the Exercise Price shall not constitute more than five percent (5.0%) of the total number of
Common Shares Deemed Outstanding at any time. |
(c) Adjustment
to Number of Warrant Shares Upon Dividends, Distributions, etc. If the Company declares or pays a dividend or distribution on
its outstanding Common Shares payable in cash, Capital Securities or other property, the Holder shall be entitled to receive, at the time
such dividend or distribution is paid, without additional cost to the Holder, the total number and kind of cash, Capital Securities or
other property which the Holder would have received had the Holder owned the Warrant Shares of record as of the date such dividend or
distribution was paid.
(d) Certificate
as to Adjustment.
(i) As
promptly as reasonably practicable following any change or adjustment of the type described above in this Section 4, but in
any event not later than ten (10) Business Days thereafter, the Company shall furnish to the Holder a certificate of an Authorized
Officer setting forth in reasonable detail such adjustment and the facts upon which it is based and certifying the calculation thereof.
(ii) As
promptly as reasonably practicable following the receipt by the Company of a written request by the Holder, but in any event not later
than ten (10) Business Days thereafter, the Company shall furnish to the Holder a certificate of an Authorized Officer certifying
the number of Warrant Shares or the amount, if any, of other shares, securities or assets then issuable upon exercise of the Warrant Certificate.
(e) Notices.
In the event that, at any time during the Exercise Period the Company shall take a record of the holders of its outstanding Common Shares
(or other Capital Securities at the time issuable upon exercise of this Warrant Certificate) for the purpose of:
(i) entitling
or enabling such holders to receive any dividend or other distribution, to receive any right to subscribe for or purchase any shares
of any class or any other securities, or to receive any other security;
(ii) (x) any
capital reorganization of the Company, any reclassification of any outstanding securities, any consolidation or merger of the Company
with or into another Person, or (y) a Sale of the Company; or
(iii) the
voluntary or involuntary dissolution, liquidation or winding-up bankruptcy or similar event involving the Company;
then, and in each such case, the Company shall
send or cause to be sent to the Holder at least ten (10) Business Days prior to the applicable record date or the applicable expected
effective date, as the case may be, for the event, a written notice specifying, as the case may be, (A) the record date for such
dividend, distribution or other right or action, and a description of such dividend, distribution or other right or action, or (B) the
effective date on which such reorganization, reclassification, consolidation, merger, Sale of the Company, dissolution, liquidation, winding-up
or bankruptcy is proposed to take place, and the date, if any is to be fixed, as of which the books of the Company shall close or a record
shall be taken with respect to which the holders of record of its Common Shares (or such other Capital Securities at the time issuable
upon exercise of the Warrant Certificate) shall be entitled to exchange their Common Shares (or such other Capital Securities), for securities
or other property deliverable upon such reorganization, reclassification, consolidation, merger, Sale of the Company, dissolution, liquidation,
winding-up or bankruptcy, and the amount per share and character of such exchange applicable to the Warrant Certificate and the Warrant
Shares. The above notwithstanding, the Company shall not be required to provide the Holder with notice containing such information if
the Company reasonably believes that it constitutes material non-public information, unless the Holder (i) confirms to the Company
in writing that it consents to receive such information, and (ii) executes a customary market standstill or equivalent agreement
pursuant to which the Holder will agree not to trade in the Company’s Common Shares or other Capital Securities while in possession
of such material non-public information or until such information is no longer material or non-public.
Section 5.
Warrant Register. The Company shall keep and properly maintain at its principal
executive offices a register (the “Warrant Register”) for the registration of this Warrant Certificate and
any transfers thereof. The Company may deem and treat the Person in whose name this Warrant Certificate is registered on such
register as the Holder thereof for all purposes, and the Company shall not be affected by any notice to the contrary, except any
assignment, division, combination or other transfer of this Warrant Certificate effected in accordance with the provisions of this
Warrant Certificate.
Section 6.
Registration Rights. The Holder is entitled to the benefit of certain registration
rights with respect to the Warrant Shares as provided in the Registration Rights Agreement, dated as of April 30, 2024, by and
between the Company and the Initial Holder (the “Registration Rights Agreement”), and any subsequent
Holder hereof shall be entitled to such rights to the extent provided in the Registration Rights Agreement. If the Company fails to
cause any Registration Statement covering applicable “Registrable Securities” (as that term is defined in the
Registration Rights Agreement) to be declared effective prior to the applicable dates set forth therein, or if any of the events
specified in Section 2(b) of the Registration Rights Agreement occurs, and the Suspension Period (as that term is defined
in the Registration Rights Agreement) (whether alone, or in combination with any other Suspension Period) continues for more than 30
consecutive days, or for more than a total of 60 days, in each case in any 360-day period, then the Expiration Date of this Warrant
Certificate shall be extended one day for each day beyond the applicable dates for effectiveness of the Registration Statement that
such Registration Statement has not been declared effective by the SEC or the 30-day or 60-day limits, as the case may be, that the
Suspension Period continues.
Section 7.
Transfer of Warrant Certificate. Subject to Section 11 hereof, this Warrant
Certificate and all rights hereunder are transferable, in whole or in part, by the Holder without charge to the Holder, upon
surrender of this Warrant Certificate to the Company at its then principal executive offices with a properly completed and duly
executed Assignment in the form attached hereto as Exhibit B. Upon such compliance, surrender and delivery, the Company
shall execute and deliver a new Warrant Certificate or Warrant Certificates in the name of the assignee or assignees and in the
denominations specified in such instrument of assignment, and shall issue to the assignor a new Warrant Certificate evidencing the
portion of this Warrant Certificate, if any, not so assigned, and this Warrant Certificate shall promptly be cancelled.
Section 8.
The Holder Not Deemed a Shareholder; Limitations on Liability. Except as otherwise specifically
provided herein (including in 4(c) above and Section 12 below), (i) prior to the Exercise Date, the
Holder shall not be entitled to receive dividends, nor shall anything contained in this Warrant Certificate be construed to confer
upon the Holder, as such, any of the rights of a shareholder of the Company or any right to receive dividends or subscription
rights, and (ii) prior to the registration of the Holder in the share register of the Company with respect to the Warrant
Shares to which the Holder is then entitled to receive upon the due exercise of this Warrant Certificate, the Holder shall not be
entitled to vote, nor shall anything contained in this Warrant Certificate be construed to confer upon the Holder, as such, any
right to vote, give or withhold consent to any corporate action (whether any reorganization, issue of shares, reclassification of
shares, consolidation, merger, conveyance or otherwise) or receive notice of meetings. In addition, nothing contained in this
Warrant Certificate shall be construed as imposing any liabilities on the Holder to purchase any securities (upon exercise of this
Warrant Certificate or otherwise) or as a shareholder of the Company, whether such liabilities are asserted by the Company or by
creditors of the Company. Notwithstanding this Section 8, the Company shall provide the Holder with copies of the same
notices and other information given to all shareholders of the Company generally, contemporaneously with the giving thereof to such
shareholders, unless such notice or information had been made publicly available on the SEC’s EDGAR system website.
Section 9.
Replacement on Loss; Division and Combination.
(a) Replacement
of Warrant Certificate on Loss. Subject to any further requirements in relation to the cancellation of this Warrant Certificate pursuant
to applicable Laws, upon receipt of evidence reasonably satisfactory to the Company of the loss, theft, destruction or mutilation of this
Warrant Certificate and upon delivery of an indemnity reasonably satisfactory to it (it being understood that a written indemnification
agreement or affidavit of loss of the Holder shall be a sufficient indemnity) and, in case of mutilation, upon surrender of such Warrant
Certificate for cancellation to the Company, the Company at its own expense shall execute and deliver to the Holder, in lieu hereof, a
new Warrant Certificate of like tenor and exercisable for an equivalent number of Warrant Shares as this Warrant Certificate so lost,
stolen, mutilated or destroyed; provided that, in the case of mutilation, no indemnity shall be required if this Warrant Certificate
in identifiable form is surrendered to the Company for cancellation.
(b)
Division and Combination of Warrant Certificate. Subject to compliance with the applicable
provisions of this Warrant Certificate as to any transfer or other assignment which may be involved in such division or combination,
this Warrant Certificate may be divided or, following any such division of this Warrant Certificate, subsequently combined with
other Warrant Certificates, upon the surrender of this Warrant Certificate or Warrant Certificates to the Company at its then
principal executive offices, together with a written notice specifying the names and denominations in which new Warrant Certificates
are to be issued, signed by each applicable Holder or its agents or attorneys. Subject to compliance with the applicable provisions
of this Warrant Certificate as to any transfer or assignment which may be involved in such division or combination, the Company
shall at its own expense execute and deliver a new Warrant Certificate or Warrant Certificates in exchange for this Warrant
Certificate or Warrant Certificates so surrendered in accordance with such notice. Such new Warrant Certificate or Warrant
Certificates shall be of like tenor to the surrendered Warrant Certificate or Warrant Certificates and shall be exercisable in the
aggregate for an equivalent number of Warrant Shares as this Warrant Certificate or Warrant Certificates so surrendered in
accordance with such notice.
Section 10. Disputes;
No Impairment, etc. The parties hereto agree as follows:
(a) Disputes.
In the event of any dispute which arises between the Holder and the Company (including the Board) with respect to the calculation or determination
of Fair Market Value, VWAP, the adjusted Exercise Price, the number of Warrant Shares, other Capital Securities, cash or other property
issuable upon exercise of this Warrant Certificate, the amount or type of consideration due to the Holder in connection with any event,
transaction or other matter described in Section 4 above or any other matter involving this Warrant Certificate or the Warrant
Shares that is not resolved by the parties after good faith discussions and efforts to reach resolution, upon the request of the Holder
the disputed issue(s) shall be submitted to a firm of independent investment bankers or public accountants of recognized national
standing, which (i) shall be chosen by the Company and be reasonably satisfactory to the Holder and (ii) shall be completely
independent of the Company (an “Independent Advisor”), for determination, and such determination by the Independent
Advisor shall be binding upon the Company and the Holder with respect to this Warrant, any Warrant Shares issued in connection herewith
or the matter in dispute, as the case may be, absent manifest error. Costs and expenses of the Independent Advisor shall be paid by the
Company.
(b)
Equitable Equivalent. In case any event shall occur as to which the provisions of Section 10(a) above
are not strictly applicable but the failure to make any adjustment would not, in the reasonable, good faith opinion of the Holder,
fairly protect the rights and benefits of the Holder represented by this Warrant Certificate in accordance with the essential intent
and principles of Section 10(a), then, in any such case, at the request of the Holder, the Company shall submit the
matter and issues raised by the Holder to an Independent Advisor, which shall give its opinion upon the adjustment, if any, on a
basis consistent with the essential intent and principles established in Section 10(a), to the extent necessary to
preserve, without dilution, the rights and benefits represented by this Warrant Certificate. Upon receipt of such opinion, the
Company will promptly mail a copy thereof to the Holder and shall make the adjustments described therein, if any. Costs and expenses
of the Independent Advisor shall be shared 50/50 by the Company and the Holder.
(c) No
Avoidance. The Company shall not, by way of amendment of any of its Charter or other Organic Documents or through any consolidation,
merger, reorganization, transfer of assets, dissolution, issue or sale of securities or any other voluntary action, avoid or seek to avoid
the observance or performance of any of the terms of this Warrant Certificate, and will at all times in good faith assist in the carrying
out of all such terms.
Section 11. Compliance
with the Securities Act.
(a) Agreement
to Comply with the Securities Act, etc.
(i) Legend.
The Holder, by acceptance of this Warrant Certificate, agrees to comply in all respects with the provisions of this Section 11
and the restrictive legend requirements set forth on the face of this Warrant Certificate and further agrees that it shall not offer,
sell or otherwise dispose of this Warrant Certificate or any Warrant Shares to be issued upon exercise hereof except under circumstances
that will not result in a violation of the Securities Act. Subject to clause (ii) below, this Warrant Certificate and all
Warrant Shares issued upon exercise of this Warrant Certificate (unless registered under the Securities Act) shall be stamped or imprinted
with a legend in substantially the following form:
“THIS WARRANT CERTIFICATE AND THE
SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE
“SECURITIES ACT”), OR QUALIFIED UNDER ANY STATE OR FOREIGN SECURITIES LAWS AND MAY NOT BE OFFERED FOR SALE, SOLD, PLEDGED,
HYPOTHECATED OR OTHERWISE TRANSFERRED OR ASSIGNED UNLESS (I) A REGISTRATION STATEMENT COVERING THE OFFER AND SALE OF SUCH SECURITIES
IS EFFECTIVE UNDER THE SECURITIES ACT AND IS QUALIFIED UNDER APPLICABLE STATE AND FOREIGN LAW OR (II) THE TRANSACTION IS EXEMPT FROM
THE REGISTRATION AND PROSPECTUS DELIVERY REQUIREMENTS UNDER THE SECURITIES ACT AND THE QUALIFICATION REQUIREMENTS UNDER APPLICABLE STATE
AND FOREIGN LAW AND, IN EACH CASE, IF THE COMPANY REQUESTS, AN OPINION SATISFACTORY TO THE COMPANY TO SUCH EFFECT HAS BEEN RENDERED
BY COUNSEL.”
(ii) Removal
of Restrictive Legends. Neither this Warrant Certificate nor any Warrant Shares issuable or deliverable under or in connection with
this Warrant Certificate shall contain any legend restricting the transfer thereof (including the legend set forth above in clause
(i)) in any of the following circumstances: (A) following any sale of this Warrant Certificate or any Warrant Shares issued or
delivered to the Holder under or in connection here with pursuant to Rule 144, (B) if this Warrant Certificate or the Warrant
Shares are, and with respect to clause (i)(2) of Rule 144 will continue to be, eligible for sale under clause (b)(1) of
Rule 144, or (C) if such legend is not required under applicable requirements of the Securities Act (including judicial interpretations
and pronouncements issued by the staff of the SEC) (collectively, the “Unrestricted Conditions”). If any of
the Unrestricted Conditions are met at the time of issuance of the Warrant Shares, to the reasonable satisfaction of the Company’s
counsel, the Warrant Shares shall be issued free of all legends.
(iii) Replacement
Warrant Certificate. The Company agrees that at such time as the Unrestricted Conditions have been satisfied it shall promptly (but
in any event within ten (10) Business Days) following written request from the Holder issue a replacement Warrant Certificate or
replacement Warrant Shares, as the case may be, free of all restrictive legends.
(iv) Sale
of Unlegended Shares. The Holder agrees that the removal of the restrictive legend from this Warrant Certificate and any certificates
representing securities as set forth in Section 11(a)(ii) above is predicated upon the Company’s reliance that
the Holder will sell this Warrant Certificate or any such securities pursuant to either an effective Registration Statement or otherwise
pursuant to the requirements of the Securities Act, including any applicable prospectus delivery requirements, or an exemption therefrom,
and that if such securities are sold pursuant to a Registration Statement, they will be sold in compliance with the plan of distribution
set forth therein.
(b)
Representations of the Holder. In connection with the issuance of this Warrant Certificate, the Holder
represents, as of the Issue Date, to the Company by acceptance of this Warrant Certificate as follows:
(i) The
Holder is an “accredited investor” as defined in Rule 501 of Regulation D promulgated under the Securities Act. The Holder
is acquiring this Warrant Certificate and the Warrant Shares to be issued upon exercise hereof for investment for its own account and
not with a view towards, or for resale in connection with, the public sale or distribution of this Warrant Certificate or the Warrant
Shares, except pursuant to sales registered or exempted under the Securities Act.
(ii) The
Holder understands and acknowledges that this Warrant Certificate and the Warrant Shares to be issued upon exercise hereof are “restricted
securities” under the Securities Act inasmuch as they are being acquired from the Company in a transaction not involving a public
offering and that, under such Laws and applicable regulations, such securities may be resold without registration under the Securities
Act only in certain limited circumstances. In addition, the Holder represents that it is familiar with Rule 144, as presently in
effect, and understands the resale limitations imposed thereby and by the Securities Act.
(iii) The
Holder acknowledges that it can bear the economic and financial risk of its investment for an indefinite period and has such knowledge
and experience in financial or business matters that it is capable of evaluating the merits and risks of the investment in this Warrant
Certificate and the Warrant Shares. The Holder has had an opportunity to ask questions and receive answers from the Company regarding
the terms and conditions of the offering of this Warrant Certificate and the business, properties, prospects and financial condition of
the Company.
Section 12. Pre-Emptive
Rights. In addition to any adjustments pursuant to Section 4 above, if at any time the Company grants, issues, offers
or sells (i) any Common Shares or (ii) any Options, Convertible Securities or rights to purchase shares, warrants, securities
or other property, in each case pro rata to the record holders of Common Shares (the “Pre-emptive Rights”),
then the Holder shall be entitled to (but shall not be obligated to) acquire, upon the same terms applicable to such Pre-emptive Rights,
the aggregate Pre-emptive Rights which the Holder would have acquired if the Holder had held the number of Warrant Shares acquirable upon
complete exercise of this Warrant Certificate immediately before the date on which a record is taken for the grant, issuance, offer or
sale of such Pre-emptive Rights, or, if no such record is taken, the date as of which the record holders of Common Shares are to be determined
for the grant, issue, offer or sale of such Pre-emptive Rights.
Section 13. Notices.
All notices, requests, consents, claims, demands, waivers and other communications hereunder shall be in writing and shall be deemed to
have been given: (i) when delivered by hand (with written confirmation of receipt); (ii) when received by the addressee if sent
by a nationally recognized overnight courier (receipt requested); (iii) on the date sent by e-mail of a PDF document (with confirmation
of transmission) if sent during normal business hours of the recipient, and on the next Business Day if sent after normal business hours
of the recipient, in each case provided that sender did not receive an automated failed delivery notification; or (iv) on the third
day after the date mailed, by certified or registered mail, return receipt requested, postage prepaid. Such communications must be sent
to the respective parties at the addresses indicated below (or at such other address for a party as shall be specified in a notice given
in accordance with this Section 13).
If to the Company: TriSalus
Life Sciences, Inc.
6272 West 91st
Avenue
Westminster, CO 80031
Attn: Sean Murphy
Email: sean.murphy@trisaluslifesci.com
with a copy to (which shall
not qualify as notice to any party hereto):
Cooley LLP
10265 Science Center Drive
San Diego, CA 92121
Attn: Matt Browne; Carlos
Ramirez
Email: mbrowne@cooley.com;
cramirez@cooley.com
If to the Holder:
OrbiMed Royalty &
Credit Opportunities IV, LP
c/o OrbiMed Advisors LLC
601 Lexington Avenue, 54th
Floor
New York, NY 10022
Attention: Matthew Rizzo;
OrbiMed Credit Report
Email: RizzoM@OrbiMed.com; ROSCreditops@orbimed.com
with a copy to (which shall
not qualify as notice to any party hereto):
Covington & Burling
LLP
The New York Times Building
620 Eighth Avenue
New York, NY 10018
Attention: Peter Schwartz;
Jennifer Uren
Email: pschwartz@cov.com;
juren@cov.com
Section 14. Cumulative
Remedies. Except to the extent expressly provided in Section 10 to the contrary, the rights and remedies provided in this
Warrant Certificate are cumulative and are not exclusive of, and are in addition to and not in substitution for, any other rights or remedies
available under applicable Laws, in equity or otherwise.
Section 15. Entire
Agreement. This Warrant Certificate constitutes the sole and entire agreement of the parties to this Warrant Certificate with respect
to the subject matter contained herein and supersedes all prior and contemporaneous understandings and agreements, both written and oral,
with respect to such subject matter.
Section 16.
Successors and Assigns. This Warrant Certificate and the rights evidenced hereby (including
under Section 6) shall be binding upon and shall inure to the benefit of the parties hereto and the successors of the
Company and the successors and permitted assigns of the Holder. Such successor or permitted assign of the Holder shall be deemed to
be the “Holder” for all purposes hereunder.
Section 17. No
Third-Party Beneficiaries. This Warrant Certificate is for the sole benefit of the Company and the Holder and their respective successors
and, in the case of the Holder, permitted assigns, and nothing herein, express or implied, is intended to or shall confer upon any other
Person any legal or equitable right, benefit or remedy of any nature whatsoever, under or by reason of this Warrant Certificate.
Section 18. Headings.
The headings in this Warrant Certificate are for reference only and shall not affect the interpretation of this Warrant Certificate.
Section 19. Amendment
and Modification; Waiver. Except as otherwise provided herein, this Warrant Certificate may only be amended, modified or supplemented
by an agreement in writing signed by each party hereto. No waiver by the Company or the Holder of any of the provisions hereof shall be
effective unless explicitly set forth in writing and signed by the party so waiving. No waiver by any party shall operate or be construed
as a waiver in respect of any failure, breach or default not expressly identified by such written waiver, whether of a similar or different
character, and whether occurring before or after that waiver. No failure to exercise, or delay in exercising, any rights, remedy, power
or privilege arising from this Warrant Certificate shall operate or be construed as a waiver thereof, nor shall any single or partial
exercise of any right, remedy, power or privilege hereunder preclude any other or further exercise thereof or the exercise of any other
right, remedy, power or privilege.
Section 20. Severability.
If any term or provision of this Warrant Certificate is invalid, illegal or unenforceable in any jurisdiction, such invalidity, illegality
or unenforceability shall not affect any other term or provision of this Warrant Certificate or invalidate or render unenforceable such
term or provision in any other jurisdiction.
Section 21. Governing
Law. This Warrant Certificate shall be governed by and construed in accordance with the internal Laws of the State of New York without
effect to any choice or conflict of Laws provision or rule (whether of the State of New York or any other jurisdiction) that would
cause the application of Laws of any jurisdiction other than those of the State of New York.
Section 22. Submission
to Jurisdiction; Waiver of Jury Trial. Except as provided in Section 10:
(a) Any
legal suit, action or proceeding arising out of or based on this Warrant Certificate or the transactions contemplated hereby may be instituted
in the federal courts of the United States or the courts of the State of New York, in each case located in the city and county of New
York. Each party irrevocably submits to the exclusive jurisdiction of such courts in any such suit, action or proceeding. Service of process,
summons, notice or other document by certified or registered mail to such party’s address set forth in Section 13 shall
be effective service of process for any suit, action or other proceeding, and the parties irrevocably and unconditionally waive any objection
to the laying of venue of any suit, action or other proceeding in such courts and irrevocably waive and agree not to plead or claim in
any such court that any such suit, action or proceeding has been brought in an inconvenient forum.
(b)
EACH PARTY ACKNOWLEDGES AND AGREES THAT ANY CONTROVERSY WHICH MAY ARISE UNDER THIS WARRANT CERTIFICATE IS
LIKELY TO INVOLVE COMPLICATED AND DIFFICULT ISSUES, AND THEREFORE EACH SUCH PARTY HEREBY IRREVOCABLY AND UNCONDITIONALLY WAIVES ANY
RIGHT SUCH PARTY MAY HAVE TO A TRIAL BY JURY WITH RESPECT TO ANY LITIGATION DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING
TO THIS WARRANT CERTIFICATE. EACH PARTY CERTIFIES AND ACKNOWLEDGES THAT (i) NO REPRESENTATIVE, AGENT OR ATTORNEY OF THE OTHER
PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER PARTY WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE
FOREGOING WAIVER, (ii) SUCH PARTY UNDERSTANDS AND HAS CONSIDERED THE IMPLICATIONS OF THIS WAIVER, (iii) SUCH PARTY MAKES
THIS WAIVER VOLUNTARILY, AND (iv) SUCH PARTY HAS BEEN INDUCED TO ENTER INTO THIS WARRANT CERTIFICATE AND EACH ANCILLARY
AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS IN THIS SECTION.
Section 23.
Counterparts. This Warrant Certificate may be executed in counterparts, each of which shall be
deemed an original, but all of which together shall be deemed to be one and the same agreement. A signed copy of this Warrant
Certificate delivered by facsimile, e-mail or other means of electronic transmission shall be deemed to have the same legal effect
as delivery of an original signed copy of this Warrant Certificate.
Section 24. No Strict Construction. This Warrant Certificate shall be construed without regard to any presumption or
rule requiring construction or interpretation against the party drafting an instrument or causing any instrument to be
drafted.
[SIGNATURE PAGE FOLLOWS]
IN WITNESS WHEREOF, the Company
has duly executed this Warrant Certificate on the Issue Date.
| TRISALUS LIFE SCIENCES, INC. |
| | |
| By: | /s/ Sean Murphy |
| Name: | Sean Murphy |
| Title: | Chief Financial Officer |
[Signature Page to Warrant Certificate]
Accepted and agreed,
ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV, LP |
|
|
|
|
|
By: |
OrbiMed ROF IV LLC, |
|
|
its General Partner |
|
|
|
|
|
|
By OrbiMed Advisors LLC, |
|
|
|
its Managing Member |
|
By: |
/s/ Matthew Rizzo |
|
|
Name: Matthew Rizzo |
|
|
Title: Member |
|
[Signature Page to Warrant Certificate]
Exhibit A
to Warrant Certificate
FORM OF EXERCISE CERTIFICATE
(To be signed only upon exercise of Warrant Certificate)
To: TriSalus
Life Sciences, Inc.
[Address]
Attention: [●]
The undersigned, as holder
of a right to purchase Warrant Shares (as defined in the Warrant Certificate) of TriSalus Life Sciences, Inc., a Delaware corporation
(the “Company”), pursuant to that certain Warrant Certificate of the Company, dated as of August 15, 2024
(the “Warrant Certificate”), a copy of which is attached to this Exercise Certificate, hereby irrevocably elects
to exercise the purchase right represented by such Warrant Certificate for, and to purchase thereunder, [ ( )]
Warrant Shares of the Company and herewith makes payment with this Exercise Certificate of the Aggregate Exercise Price therefor by the
following method:
The undersigned hereby elects
to make payment of the Aggregate Exercise Price of [ Dollars ($ )]
for ( ) Common Shares using the method described in Section 3(b)(i).
The undersigned hereby elects
to make payment of the Aggregate Exercise Price of [ Dollars ($ )]
for ( ) Common Shares using the method described in Section 3(b)(ii).
The undersigned hereby elects
to make payment of the Aggregate Exercise Price of [ Dollars ($ )]
for ( ) Common Shares using the method described in Section 3(b)(iii).
Unless otherwise defined herein,
capitalized terms have the meanings provided in the Warrant Certificate.
DATED:__________
Exhibit B
to Warrant Certificate
FORM OF ASSIGNMENT
[DATE OF ASSIGNMENT]
THE UNDERSIGNED, [NAME OF
HOLDER], is the holder (in such capacity, the “Holder”) of a warrant certificate issued by TriSalus Life Sciences, Inc.,
a Delaware corporation (the “Warrant Certificate” and the “Company”, respectively),
entitling the Holder to purchase up to [ ] Warrant Shares (as defined in the
Warrant Certificate). Unless otherwise defined, capitalized terms used herein have the meanings ascribed thereto in the Warrant Certificate.
FOR VALUE RECEIVED, the Holder
hereby sells, assigns and transfers to [NAME OF ASSIGNEE] (the “Assignee”) the right to acquire [all Warrant
Shares entitled to be purchased upon exercise of the Warrant Certificate] [
of the Warrant Shares entitled to be purchased upon exercise of the Warrant Certificate]. In furtherance of the foregoing assignment,
the Holder hereby irrevocably instructs the Company to (i) memorialize such assignment on the Warrant Register as required pursuant
to Section 5 of the Warrant Certificate, and (ii) pursuant to Section 7 of the Warrant Certificate, execute
and deliver to the Assignee [and the Holder][a new Warrant Certificate][new Warrant Certificates] reflecting the foregoing assignment
([each] a “Substitute Warrant Certificate”).
The Assignee acknowledges
and agrees that its Substitute Warrant Certificate and the Warrant Shares to be issued upon exercise thereof are being acquired for investment
and that the Assignee will not offer, sell or otherwise dispose of its Substitute Warrant Certificate or any Warrant Shares to be issued
upon exercise or conversion thereof except under circumstances which will not result in a violation of the Securities Act or any applicable
state securities laws. The Assignee represents and warrants for the benefit of the Company that the Assignee is an “accredited investor”
within the meaning of Rule 501 of Regulation D promulgated under the Securities Act.
To the extent required pursuant
to Section 11(a) of the Warrant Certificate, the Assignee acknowledges and agrees that a restrictive legend shall be
applied to the Assignee’s Substitute Warrant Certificate and the Warrant Shares issuable upon exercise of such certificate substantially
consistent with the legend set forth in Section 11(a)(i).
[SIGNATURE PAGE FOLLOWS]
IN WITNESS WHEREOF, the parties
hereto agree as set forth above as of the date first written above.
Accepted and agreed,
[NAME OF ASSIGNEE] | |
| | |
By | | |
| Name: | |
| Title: | |
Exhibit 4.11
Execution Version
WARRANT CERTIFICATE
THIS WARRANT CERTIFICATE AND
THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED
(THE “SECURITIES ACT”), OR QUALIFIED UNDER ANY STATE OR FOREIGN SECURITIES LAWS AND MAY NOT BE OFFERED FOR SALE, SOLD,
PLEDGED, HYPOTHECATED OR OTHERWISE TRANSFERRED OR ASSIGNED UNLESS (I) A REGISTRATION STATEMENT COVERING THE OFFER AND SALE OF SUCH
SECURITIES IS EFFECTIVE UNDER THE SECURITIES ACT AND IS QUALIFIED UNDER APPLICABLE STATE AND FOREIGN LAW OR (II) THE TRANSACTION
IS EXEMPT FROM THE REGISTRATION AND PROSPECTUS DELIVERY REQUIREMENTS UNDER THE SECURITIES ACT AND THE QUALIFICATION REQUIREMENTS UNDER
APPLICABLE STATE AND FOREIGN LAW AND, IN EACH CASE, IF THE COMPANY REQUESTS, AN OPINION SATISFACTORY TO THE COMPANY TO SUCH
EFFECT HAS BEEN RENDERED BY COUNSEL.
Warrant Shares Issuable: | 38,004
Common Shares |
| |
Issue Date: | August 15,
2024 (Substitute Warrant Certificate #2 to Initial Certificate April 30, 2024) |
FOR VALUE RECEIVED, TRISALUS
LIFE SCIENCES, INC., a Delaware corporation (the “Company”), hereby certifies that ORBIMED ROYALTY &
CREDIT OPPORTUNITIES IV OFFSHORE, LP, a Delaware limited partnership (together with its successors and permitted transferees and assigns,
a “Holder”) is entitled to purchase, at the per share Exercise Price, up to Thirty-Eight Thousand and Four (38,004)
fully paid and nonassessable Common Shares (as subject to adjustment hereunder, the “Warrant Shares”), all subject
to the terms, conditions and adjustments set forth below in this Warrant Certificate. Certain capitalized terms used herein are defined
in Section 1.
This Warrant Certificate is
being issued as a Substitute Warrant Certificate as defined in and pursuant to the Assignment dated August 15, 2024, by and between
OrbiMed Royalty & Credit Opportunities IV, LP (the “Initial Holder”) and Holder with respect to the
Warrant Certificate issued April 30, 2024 (the “Initial Certificate”). The Initial Certificate was issued
as a condition precedent to the making of loans under and pursuant to the Credit Agreement, dated as of April 30, 2024 (as amended
or otherwise modified from time to time, the “Credit Agreement”), among TriSalus Operating Life Sciences, Inc.,
as borrower, the Company, the lenders party thereto, and OrbiMed Royalty & Credit Opportunities IV, LP, as the administrative
agent.
Section 1. Definitions.
Capitalized terms used in this Warrant Certificate but not defined herein have the meanings ascribed thereto in the Credit Agreement as
in effect on the date hereof. The following terms when used herein have the following meanings:
“Aggregate Exercise
Price” means, with respect to any exercise of this Warrant Certificate for Warrant Shares, an amount equal to the product
of (i) the number of Warrant Shares in respect of which this Warrant Certificate is then being exercised pursuant to Section 3,
multiplied by (ii) the Exercise Price.
“Bloomberg”
has the meaning set forth within the definition of “VWAP”.
“Cashless Exercise”
has the meaning set forth in Section 3(b).
“Charter”
means the Second Amended and Restated Certificate of Incorporation of the Company, as amended as of August 10, 2023.
“Common Shares”
means the Company’s common stock, par value $0.0001 per share.
“Common Shares
Deemed Outstanding” means, at any given time, the sum of (i) the number of Common Shares actually outstanding at such
time, plus (ii) the number of Common Shares issuable upon exercise of Options actually outstanding at such time, plus (iii) the
number of Common Shares issuable upon conversion or exchange of Convertible Securities actually outstanding at such time (treating as
actually outstanding any Convertible Securities issuable upon exercise of Options actually outstanding at such time), in each case, regardless
of whether the Options or Convertible Securities are actually exercisable at such time; provided that Common Shares Deemed Outstanding
at any given time shall not include shares owned or held by or for the account of the Company or any or its wholly owned subsidiaries.
“Company”
has the meaning set forth in the preamble.
“Convertible Securities”
means any Capital Securities that, directly or indirectly, are convertible into, exchangeable or settleable for Common Shares, including
shares of the Company’s preferred stock that may be issued from time to time.
“Credit Agreement”
has the meaning set forth in the preamble.
“Determination
Date” has the meaning set forth in the definition of “VWAP”.
“Exchange Act”
means the Securities Exchange Act of 1934, as amended.
“Exercise Certificate”
has the meaning set forth in Section 3(a)(i).
“Exercise Date”
means, for any given exercise of this Warrant Certificate, whether in whole or in part, a Business Day on which the conditions to such
exercise as set forth in Section 3 shall have been satisfied at or prior to 5:00 p.m., New York City time, including, without
limitation, the receipt by the Company of the Exercise Certificate.
“Exercise Period”
means the period from (and including) the Issue Date to (and including) 5:00 p.m., New York City time, on the Expiration Date.
“Exercise Price”
means $9.5562, as adjusted from time to time pursuant to Section 4.
“Expiration Date”
means April 30, 2031.
“Fair Market Value”
means (i) if the Common Shares are traded on a Trading Market, the VWAP of such Common Shares for such day (provided that if the
Fair Market Value is being determined in connection with a Sale of the Company, such Fair Market Value shall be the greater of the amount
determined pursuant to this clause (i) and the closing price on the Trading Market on the Trading Day immediately prior to the closing
date of the Sale of the Company) or (ii) if at any time the Common Shares are not listed, quoted or otherwise available for trading
on any Trading Market (so that no Trading Day shall have occurred), or if VWAP cannot be calculated for the Common Shares for such day
for any other reason, the “Fair Market Value” of such Common Shares shall be the fair market value per share
of such Common Shares as determined jointly by the Company and the Holder; provided further, that, in the event the Company and
Holder are unable to so mutually agree, Fair Market Value shall be determined pursuant to Section 10(a).
“Holder”
has the meaning set forth in the preamble.
“Independent Advisor”
has the meaning set forth in Section 10(a).
“Initial Holder”
has the meaning set forth in the preamble.
“Issue Date”
means the date designated as such on the first page of this Warrant Certificate.
“Marketable Securities”
means equity securities meeting each of the following requirements: (i) the issuer thereof is subject to the reporting requirements
of Section 13 or Section 15(d) of the Exchange Act, and is current in its filing of all required reports and other information
under the Securities Act and the Exchange Act; (ii) such equity securities are traded on a Trading Market; and (iii) if delivered
(or to be delivered) as payment or compensation to the Holder in connection with an automatic Cashless Exercise pursuant to Section 3(c),
following the closing of the related Sale of the Company, the Holder would not be restricted from publicly re-selling all of such equity
securities delivered to it.
“Nasdaq”
means The Nasdaq Stock Market LLC.
“NYSE”
means the New York Stock Exchange.
“Options”
means any warrants, options or similar rights to subscribe for or purchase Common Shares or Convertible Securities.
“Original Issue
Date” means April 30, 2024.
“OTC Bulletin
Board” means the Financial Industry Regulatory Authority, Inc. OTC Bulletin Board.
“Pre-emptive Rights”
has the meaning set forth in Section 12.
“Registration
Statement” means, in connection with any public offering of securities, any registration statement required pursuant to
the Securities Act that covers the offer and sales of any such securities, including any prospectus, amendments or supplements to such
Registration Statement, including post-effective amendments and all exhibits and all materials incorporated by reference in such Registration
Statement.
“Rule 144”
means Rule 144 promulgated under the Securities Act.
“Sale of the Company”
means a transaction pursuant to which (i) (x) any Person or group of Persons acting jointly or otherwise in concert (other than
the Holder and any other parties to the Credit Agreement) acquires ownership, directly or indirectly, beneficially or of record, of Capital
Securities of the Company having more than fifty percent (50%) of the aggregate economic interests and/or voting power, determined on
a fully diluted basis, (y) any Person or group of Persons acting jointly or otherwise in concert (other than the Holder and any other
parties to the Credit Agreement) acquires, by contract or otherwise, the right to appoint or elect a majority of the Company’s board
of directors (the “Board”), or (z) all or substantially all of the assets of the Company and its Subsidiaries,
taken as a whole, are sold, leased, exclusively licensed, transferred, conveyed or otherwise disposed of, and (ii) all Obligations
outstanding under the Credit Agreement are to be paid in full in cash, whether pursuant to the terms of the transaction, pursuant to the
terms of the Credit Agreement or otherwise.
“SEC”
means the Securities and Exchange Commission or any successor thereto.
“Share Distribution”
means any issuance or sale by the Company of any of its Common Shares, Options or Convertible Securities, other than in connection with
a dividend or distribution to holders of its Common Shares of the type described in Section 4(c) below.
“Share Reorganization”
has the meaning set forth in Section 4(a).
“Trading Day”
means, with respect to the Common Shares or any other Marketable Securities, a date on which the relevant Trading Market is open and conducting
business.
“Trading Market”
means, with respect to the Common Shares or any other Marketable Securities, the Nasdaq, the NYSE or the OTC Bulletin Board.
“Unrestricted
Conditions” has the meaning set forth in Section 11(a)(ii).
“VWAP”
means, with respect to any Common Shares, as of any day of determination (a “Determination Date”), the volume
weighted average sale price for the period of ten (10) consecutive Trading Days immediately preceding such Determination Date on
the Trading Market for such Common Shares as reported by, or based upon data reported by, Bloomberg Financial Markets or an equivalent,
reliable reporting service reasonably acceptable to the Holder and the Company (collectively, “Bloomberg”) or,
if the volume weighted average sale price has not been reported for such security by Bloomberg for such ten (10) day period, then
the simple average of the last closing trade prices of such security for such ten (10) day period, as reported by Bloomberg, or,
if no last closing trade price is reported for such security by Bloomberg, the simple average of the bid prices of any market makers for
such security that are listed in the over the counter market by the Financial Industry Regulatory Authority, Inc. or on the OTC Bulletin
Board (or any successor) or in the “pink sheets” (or any successor) by the OTC Markets Group, Inc. over such ten (10) day
period.
“Warrant Certificate”
means this Warrant Certificate and all subsequent warrant certificates issued upon division, combination or transfer of, or in substitution
for, this Warrant Certificate.
“Warrant Register”
has the meaning set forth in Section 5.
“Warrant Shares”
has the meaning set forth in the preamble.
Section 2. Term
of Warrant Certificate. Subject to the terms and conditions hereof, from time to time during the Exercise Period, the Holder of this
Warrant Certificate may exercise this Warrant Certificate for all or any part of the Warrant Shares purchasable hereunder (subject to
adjustment as provided herein).
Section 3. Exercise
of Warrant Certificate.
(a) Exercise
Procedure. This Warrant Certificate may be exercised from time to time on any Business Day during the Exercise Period, for all or
any part of the unexercised Warrant Shares, upon:
(i) delivery
to the Company at its then registered office of a duly completed and executed Exercise Certificate in the form attached hereto as Exhibit A
(each, an “Exercise Certificate”), which certificate will specify the number of Warrant Shares to be purchased
and the Aggregate Exercise Price; and
(ii) simultaneously
with the delivery of the Exercise Certificate, payment to the Company of the Aggregate Exercise Price in accordance with Section 3(b).
(b) Payment
of the Aggregate Exercise Price. Payment of the Aggregate Exercise Price shall be made, at the option of the Holder as set forth in
the applicable Exercise Certificate, by any of the following methods:
(i) by
wire transfer of immediately available funds to an account designated in writing by the Company, in the amount of such Aggregate Exercise
Price;
(ii) by
instructing the Company to withhold a number of Warrant Shares then issuable upon exercise of this Warrant Certificate with an aggregate
Fair Market Value as of the Exercise Date equal to such Aggregate Exercise Price; or
(iii) any
combination of the foregoing.
In the event of any withholding of Warrant Shares
pursuant to Section 3(b)(ii) or (iii) (solely to the extent of such withholding, a “Cashless
Exercise”) where the number of shares whose value is equal to the Aggregate Exercise Price is not a whole number, the number
of shares withheld by the Company shall be rounded up to the nearest whole share and the Company shall make a cash payment to the Holder
(by delivery of a certified or official bank check or by wire transfer of immediately available funds) based on the incremental fraction
of a share being so withheld by the Company in an amount equal to the product of (x) such incremental fraction of a share being so
withheld multiplied by (y) the Fair Market Value per Warrant Share as of the Exercise Date.
(c) Automatic
Cashless Exercise. To the extent this Warrant Certificate has not been exercised in full by the Holder prior to the earlier of (i) the
occurrence of the Expiration Date, and (ii) the date on which a Sale of the Company is consummated pursuant to which the sole consideration
payable to the Company or its shareholders in respect of such sale transaction consists of cash, Marketable Securities or a combination
thereof, any portion of this Warrant Certificate that remains unexercised on such date shall be deemed to have been exercised automatically
pursuant to a Cashless Exercise, in whole (and not in part), on the Business Day immediately preceding such date; provided, that
the automatic Cashless Exercise contemplated by this Section 3(c) shall not occur in the event that, as of the Business
Day immediately preceding any such date described above, the per share Fair Market Value of a Warrant Share is less than the Exercise
Price per Warrant Share, in which case, this Warrant Certificate shall automatically expire and be of no further force and effect as of
the Expiration Date or immediately prior to the consummation of the Sale of the Company, as applicable.
To the extent permitted by applicable Law, for
purposes of Rule 144, (i) the Warrant Shares issuable upon any exercise of this Warrant Certificate in any Cashless Exercise
transaction shall be deemed to have been acquired on the Original Issue Date, and (ii) the holding period for any Warrant Shares
issuable upon the exercise of this Warrant Certificate in any Cashless Exercise transaction shall be deemed to have commenced on the Original
Issue Date; provided that the Company makes no representation or warranty regarding the commencement of the holding period of any
Warrant Share.
(d) Delivery
of Stock Certificates. With respect to any exercise of this Warrant Certificate by the Holder, upon receipt by the Company of an Exercise
Certificate and delivery of the Aggregate Exercise Price, the Company shall, within five (5) Business Days, deliver in accordance
with the terms hereof to or upon the order of the Holder that number of Warrant Shares for the portion of this Warrant Certificate so
exercised on such date, together with cash in lieu of any fraction of a share to the extent the Company elects to do so pursuant to Section 3(e) below.
If such Warrant Shares are issued in certificated form, the Company shall deliver a certificate or certificates, to the extent possible,
representing the number of Warrant Shares as the Holder shall request in the Exercise Certificate. If such Warrant Shares are issued in
uncertificated form, the Company shall deliver upon request a confirmation evidencing the registration of such shares. Unless otherwise
provided herein, upon any exercise in accordance with the terms of this Warrant Certificate, this Warrant Certificate shall be deemed
to have been exercised and such certificate or certificates of Warrant Shares shall be deemed to have been issued, and the Holder shall
be deemed to have become a holder of record of such Warrant Shares for all purposes, as of the Exercise Date. Unless otherwise permitted
by federal or state securities laws, rules or regulations, any share certificates issued pursuant to the exercise of this Warrant
Certificate will bear a legend in substantially the form set out in Section 11(a)(i) below.
(e) No
Fractional Shares or Scrip. No fractional or scrip representing fractional shares shall be issued upon the exercise of this Warrant
Certificate. As to any fraction of a share which the Holder would otherwise be entitled to purchase upon such exercise, the Company shall
at its election, either pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied by the
Fair Market Value of one Warrant Share on the Exercise Date or round up to the next whole share.
(f) Surrender
of this Warrant Certificate; Delivery of New Warrant Certificate.
(i) The
Holder shall not be required to physically surrender this Warrant Certificate to the Company until this Warrant Certificate has been exercised
in full by the Holder, in which case, the Holder shall, at the written request of the Company, surrender this Warrant Certificate to the
Company for cancellation within three (3) Business Days after the date the final Exercise Certificate is delivered to the Company.
Partial exercises of this Warrant Certificate resulting in purchases of a portion of the total number of Warrant Shares available hereunder
shall have the effect of lowering the outstanding number of Warrant Shares issuable hereunder by an amount equal to the applicable number
of Warrant Shares that have been issued hereunder as a result of previous exercises or withheld in connection with any Cashless Exercises.
The Holder and the Company shall maintain records showing the number of Warrant Shares issued and purchased, the date of such issuances
and purchases and the number of Warrant Shares withheld in connection with any Cashless Exercises. The Holder and any assignee, by acceptance
of this Warrant Certificate, acknowledge and agree that, by reason of the provisions of this Section 3(f), following the purchase
of a portion of the Warrant Shares hereunder, the number of Warrant Shares available for purchase hereunder at any given time may be fewer
than the amount stated on the face hereof.
(ii) Notwithstanding
the foregoing, to the extent that there are unexpired and unexercised Warrant Shares remaining under the Warrant Certificate, the Holder
may request that the Company (and the Company shall), at the time of issuance of any Warrant Shares in accordance with Section 3(d) and
the surrender of this Warrant Certificate, deliver to the Holder a new Warrant Certificate evidencing the rights of the Holder to subscribe
for the unexpired and unexercised Warrant Shares called for by this Warrant Certificate. Unless otherwise agreed upon by the Holder in
its sole discretion, such new Warrant Certificate shall in all other respects be identical to this Warrant Certificate.
(g) Valid
Issuance of Warrant Certificate and Warrant Shares; Payment of Taxes. With respect to the exercise of this Warrant Certificate, the
Company hereby represents, warrants, covenants and agrees as follows:
(i) This
Warrant Certificate is, and any Warrant Certificate issued in substitution for or replacement of this Warrant Certificate shall be, upon
issuance, duly authorized.
(ii) All
Warrant Shares issuable upon the exercise of this Warrant Certificate (or any substitute or replacement Warrant Certificate) shall be,
upon issuance, and the Company shall take all such actions as may be necessary or appropriate in order that such Warrant Shares are, validly
issued, fully paid and non-assessable, issued without violation of any preemptive or similar rights of any shareholder of the Company
and free and clear of all liens and charges (other than liens or charges created by the Holder, or created with regard to income taxes
or other taxes payable by the Holder incurred in connection with the exercise of the Warrant or taxes in respect of any transfer made
by the Holder occurring contemporaneously therewith).
(iii) The
Company shall take all such actions as may be necessary to (x) comply with Section 3(i) below and (y) ensure
that all such Warrant Shares are issued without violation by the Company of any applicable Law or any requirements of any foreign or domestic
securities exchange upon which Warrant Shares may be listed at the time of such exercise.
(iv) The
Company shall exclusively bear and pay all expenses in connection with, and all governmental charges, taxes, fees, levies, withholdings
and all other such payments, that may be imposed on or with respect to, the issuance of this Warrant Certificate, and the issuance or
delivery of Warrant Shares pursuant to the terms of this Warrant Certificate and the Holder shall not be affected by such payments, and
the Company shall not be eligible to any indemnification for such payment from the Holder.
(v) The
Company is a corporation duly organized and validly existing under the Laws of the State of Delaware and has the capacity and corporate
power and authority to enter into this Warrant Certificate.
(vi) The
Company has taken all action required to be taken to authorize the execution, delivery and performance of this Warrant Certificate.
(vii) This
Warrant Certificate has been duly executed by the Company.
(viii) The
obligations of the Company under this Warrant Certificate are legal, valid and binding obligations, enforceable against the Company in
accordance with the terms hereof, except to the extent that enforceability may be limited by bankruptcy, insolvency, reorganization, moratorium
or similar laws affecting creditors’ rights generally and by general equitable principles.
(ix) As
of the Issue Date, the Company has complied with all obligations set forth in Section 3(i), below.
(h)
Conditional Exercise. Notwithstanding any other provision hereof, if an exercise of all or any
portion of this Warrant Certificate is to be made in connection with a Sale of the Company, such exercise may, at the election of
the Holder, be conditioned upon the consummation of such transaction, in which case such exercise shall not be deemed to be
effective until immediately prior to the consummation of such transaction.
(i)
Reservation of Shares. The Company shall at all times during the Exercise Period reserve and keep
available out of its authorized but unissued Common Shares or (if applicable) other securities constituting Warrant Shares, solely
for the purpose of issuance upon the exercise of this Warrant Certificate, the maximum number of Warrant Shares issuable upon the
exercise of this Warrant Certificate. The Company shall not increase the par value of any Warrant Shares receivable upon the
exercise of this Warrant Certificate above the Exercise Price then in effect, and shall take all such actions within its power as
may be necessary or appropriate in order that the Company may validly and legally issue fully paid and nonassessable Warrant Shares
upon the exercise of this Warrant Certificate.
(j)
Rule 144 Compliance. With a view to making available to the Holder the benefits of Rule 144 and any
other rule or regulation of the SEC that may at any time permit a holder to sell securities of the Company to the public
without registration or pursuant to a Registration Statement, the Company shall, during the Exercise Period while any portion of
this Warrant Certificate remains unexercised:
(i) use
commercially reasonable efforts to make and keep adequate public information available, as required by clause (c) of Rule 144;
(ii) use
commercially reasonable efforts to file with the SEC in a timely manner all reports and other documents required of the Company under
the Securities Act and the Exchange Act (excluding, for avoidance of doubt, any prospectus or registration statement which the Company
is under no obligation to file); and
(iii) furnish,
or otherwise make available to the Holder so long as the Holder owns Warrant Shares, promptly upon request, a written statement by the
Company as to its compliance with the reporting requirements of Rule 144 and the Exchange Act, a copy of the most recent annual or
quarterly report of the Company, and such other reports and documents so filed or furnished by the Company with the SEC under the Exchange
Act or Securities Act as the Holder may reasonably request in connection with the sale of Common Shares without registration.
(k) Ownership
Cap. The Company shall not knowingly effect the exercise of this Warrant Certificate, and the Holder shall not have the right to exercise
this Warrant Certificate to the extent that, after giving effect to such exercise, the Holder (together with its Affiliates) would beneficially
own in excess of 9.99% of the Common Shares of the Company immediately after giving effect to such exercise. For purposes of the foregoing
sentence, the aggregate number of Common Shares owned by the Holder and its Affiliates shall include the number of Warrant Shares issuable
upon exercise of this Warrant Certificate with respect to which the determination of such aggregate number is being made, but shall exclude
Common Shares (if any) that would be issuable upon (i) exercise of the remaining, unexercised portion of this Warrant Certificate
beneficially owned by the Holder and its Affiliates and (ii) exercise or conversion of the unexercised or unconverted portion of
any other Capital Securities of the Company beneficially owned by the Holder and its Affiliates (including, without limitation, any Convertible
Securities) subject to a limitation on conversion or exercise analogous to the limitations contained herein. Except as set forth in the
preceding sentence, for purposes of this Section 3(k), beneficial ownership shall be calculated in accordance with Section 13(d) of
the Exchange Act. For purposes of this Warrant Certificate, in determining the number of outstanding Common Shares, the Holder of this
Warrant Certificate may rely on the number of such outstanding Capital Securities as reflected in the most recent of (i) the Company’s
Form 10-K, Form 10-Q or other public filing with the SEC, as the case may be, if available, (ii) a more recent public announcement
by the Company, or (iii) any other notice by the Company or its transfer agent setting forth the number of outstanding Common Shares.
In addition, upon the written request of the Holder (but not more than once during any calendar quarter), the Company shall, within three
(3) Business Days, confirm to the Holder the number of its outstanding Common Shares. Furthermore, upon the written request of the
Company (but not more than once during any calendar quarter), the Holder shall promptly confirm to the Company its then current beneficial
ownership with respect to the Company’s Common Shares.
(l) Except
as expressly provided herein with respect to cash payments in lieu of the issuance of fractional shares, and without regard to any exchange
of consideration in connection with an automatic Cashless Exercise pursuant to Section 3(c) above or similar event, upon
exercise of this Warrant Certificate the Holder shall not otherwise be entitled to receive cash or Warrant Shares that are registered
under the Securities Act.
Section 4. Adjustment
to Number of Warrant Shares, Exercise Price, etc. The number of Warrant Shares issuable upon exercise of this Warrant Certificate
shall be subject to adjustment from time to time as provided in this Section 4.
(a) Adjustment
to Number of Warrant Shares Upon Reorganizations, Reclassifications, etc. In the event of any changes in the outstanding Common
Shares of the Company by reason of redemptions, recapitalizations, reclassifications, combinations or exchanges of shares, splits or reverse
splits, separations, reorganizations, liquidations, substitutions, replacements or the like (any of the foregoing or combination thereof
being a “Share Reorganization”), the number and class of Warrant Shares available upon exercise of this Warrant
Certificate in the aggregate and the Exercise Price shall be correspondingly adjusted to give the Holder of this Warrant Certificate,
on exercise for the same Aggregate Exercise Price, the total number, class, and kind of shares as the Holder would have owned had this
Warrant Certificate been exercised prior to any such event and had the Holder continued to hold such Warrant Shares until after the event
requiring adjustment. The form of this Warrant Certificate need not be changed because of any adjustment in the number of Warrant Shares
subject to this Warrant Certificate.
(b) Adjustment
to Exercise Price Upon a Share Distribution. Subject to clause (iii) below, if the Company consummates or effects
any Share Distribution for a price per Common Share less than the Exercise Price then in effect, then, effective upon such Share Distribution,
the Exercise Price shall be reduced to a price determined by multiplying the Exercise Price then in effect by a fraction, the numerator
of which shall be the sum of (A) the number of Common Shares Deemed Outstanding immediately prior to such Share Distribution multiplied
by the Exercise Price then in effect, plus (B) the consideration, if any, received by the Company upon such Share Distribution, and
the denominator of which shall be the product of (1) the total number of Common Shares Deemed Outstanding immediately after such
Share Distribution multiplied by (2) the Exercise Price in effect immediately prior to such Share Distribution. For purposes of this
Section 4(b):
(i) In
the event Options or Convertible Securities are included in any such Share Distribution, the price per Common Share deemed to have been
issued or sold as a result of the sale or issuance of such Options or Convertible Securities, shall be equal to the price per Common Share
for which Common Shares are issuable upon the exercise of such Options or upon conversion or exchange of such Convertible Securities,
as the case may be (determined by dividing (x) the aggregate amount, if any, received or receivable by the Company as consideration
for the issuance, sale, distribution or grant of all such Options or Convertible Securities, plus the minimum aggregate amount of additional
consideration payable to the Company, if any, upon the exercise of all such Options or the conversion or exchange of all such Convertible
Securities (as the case may be), by (y) the total maximum number of Common Shares issuable upon the exercise of all such Options
or upon the conversion or exchange of all such Convertible Securities (without, in each case, giving effect to any anti-dilution provisions
included in such Options or Convertible Securities that are not applicable at the time of the applicable price per Common Share calculations)).
(ii) The
provisions of this Section 4(b) shall not in any event operate to increase the Exercise Price.
(iii) This
Section 4(b) shall not apply to any of the following:
| (A) | Any issuance, sale or other distribution of Common Shares, Options or Convertible Securities pursuant
to (i) any Share Reorganization, which shall instead be governed by Section 4(a) above, or (ii) any dividend
or distribution to holders of Common Shares, which shall instead by governed by Section 4(c) below. |
| (B) | The issuance of Common Shares upon exercise or conversion of any Options or Convertible Securities included
in the Common Shares Deemed Outstanding as of the Original Issue Date. |
| (C) | The grant or issuance of Common Shares, Options or Convertible Securities to board members, officers,
employees, consultants or other service providers of the Company pursuant to any employee incentive plan, employee share purchase plan
or similar equity-based benefit plans (including any inducement award granted in accordance with the Nasdaq Listing Rules) approved by
the Company’s Board or duly authorized committee thereof; provided that the total number of securities issued under this
sub-clause for a price per share less than the Exercise Price shall not constitute more than five percent (5.0%) of the total number of
Common Shares Deemed Outstanding at any time. |
(c) Adjustment
to Number of Warrant Shares Upon Dividends, Distributions, etc. If the Company declares or pays a dividend or distribution on
its outstanding Common Shares payable in cash, Capital Securities or other property, the Holder shall be entitled to receive, at the time
such dividend or distribution is paid, without additional cost to the Holder, the total number and kind of cash, Capital Securities or
other property which the Holder would have received had the Holder owned the Warrant Shares of record as of the date such dividend or
distribution was paid.
(d)
Certificate as to Adjustment.
(i) As
promptly as reasonably practicable following any change or adjustment of the type described above in this Section 4, but in
any event not later than ten (10) Business Days thereafter, the Company shall furnish to the Holder a certificate of an Authorized
Officer setting forth in reasonable detail such adjustment and the facts upon which it is based and certifying the calculation thereof.
(ii) As
promptly as reasonably practicable following the receipt by the Company of a written request by the Holder, but in any event not later
than ten (10) Business Days thereafter, the Company shall furnish to the Holder a certificate of an Authorized Officer certifying
the number of Warrant Shares or the amount, if any, of other shares, securities or assets then issuable upon exercise of the Warrant Certificate.
(e) Notices.
In the event that, at any time during the Exercise Period the Company shall take a record of the holders of its outstanding Common Shares
(or other Capital Securities at the time issuable upon exercise of this Warrant Certificate) for the purpose of:
(i) entitling
or enabling such holders to receive any dividend or other distribution, to receive any right to subscribe for or purchase any shares of
any class or any other securities, or to receive any other security;
(ii) (x) any
capital reorganization of the Company, any reclassification of any outstanding securities, any consolidation or merger of the Company
with or into another Person, or (y) a Sale of the Company; or
(iii) the
voluntary or involuntary dissolution, liquidation or winding-up bankruptcy or similar event involving the Company;
then, and in each such case, the Company shall
send or cause to be sent to the Holder at least ten (10) Business Days prior to the applicable record date or the applicable expected
effective date, as the case may be, for the event, a written notice specifying, as the case may be, (A) the record date for such
dividend, distribution or other right or action, and a description of such dividend, distribution or other right or action, or (B) the
effective date on which such reorganization, reclassification, consolidation, merger, Sale of the Company, dissolution, liquidation, winding-up
or bankruptcy is proposed to take place, and the date, if any is to be fixed, as of which the books of the Company shall close or a record
shall be taken with respect to which the holders of record of its Common Shares (or such other Capital Securities at the time issuable
upon exercise of the Warrant Certificate) shall be entitled to exchange their Common Shares (or such other Capital Securities), for securities
or other property deliverable upon such reorganization, reclassification, consolidation, merger, Sale of the Company, dissolution, liquidation,
winding-up or bankruptcy, and the amount per share and character of such exchange applicable to the Warrant Certificate and the Warrant
Shares. The above notwithstanding, the Company shall not be required to provide the Holder with notice containing such information if
the Company reasonably believes that it constitutes material non-public information, unless the Holder (i) confirms to the Company
in writing that it consents to receive such information, and (ii) executes a customary market standstill or equivalent agreement
pursuant to which the Holder will agree not to trade in the Company’s Common Shares or other Capital Securities while in possession
of such material non-public information or until such information is no longer material or non-public.
Section 5.
Warrant Register. The Company shall keep and properly maintain at its principal executive offices a
register (the “Warrant Register”) for the registration of this Warrant Certificate and any transfers
thereof. The Company may deem and treat the Person in whose name this Warrant Certificate is registered on such register as the
Holder thereof for all purposes, and the Company shall not be affected by any notice to the contrary, except any assignment,
division, combination or other transfer of this Warrant Certificate effected in accordance with the provisions of this Warrant
Certificate.
Section 6. Registration
Rights. The Holder is entitled to the benefit of certain registration rights with respect to the Warrant Shares as provided in the
Registration Rights Agreement, dated as of April 30, 2024, by and between the Company and the Initial Holder (the “Registration
Rights Agreement”), and any subsequent Holder hereof shall be entitled to such rights to the extent provided in the Registration
Rights Agreement. If the Company fails to cause any Registration Statement covering applicable “Registrable Securities” (as
that term is defined in the Registration Rights Agreement) to be declared effective prior to the applicable dates set forth therein, or
if any of the events specified in Section 2(b) of the Registration Rights Agreement occurs, and the Suspension Period (as that
term is defined in the Registration Rights Agreement) (whether alone, or in combination with any other Suspension Period) continues for
more than 30 consecutive days, or for more than a total of 60 days, in each case in any 360-day period, then the Expiration Date of this
Warrant Certificate shall be extended one day for each day beyond the applicable dates for effectiveness of the Registration Statement
that such Registration Statement has not been declared effective by the SEC or the 30-day or 60-day limits, as the case may be, that the
Suspension Period continues.
Section 7. Transfer
of Warrant Certificate. Subject to Section 11 hereof, this Warrant Certificate and all rights hereunder are transferable,
in whole or in part, by the Holder without charge to the Holder, upon surrender of this Warrant Certificate to the Company at its then
principal executive offices with a properly completed and duly executed Assignment in the form attached hereto as Exhibit B.
Upon such compliance, surrender and delivery, the Company shall execute and deliver a new Warrant Certificate or Warrant Certificates
in the name of the assignee or assignees and in the denominations specified in such instrument of assignment, and shall issue to the assignor
a new Warrant Certificate evidencing the portion of this Warrant Certificate, if any, not so assigned, and this Warrant Certificate shall
promptly be cancelled.
Section 8. The
Holder Not Deemed a Shareholder; Limitations on Liability. Except as otherwise specifically provided herein (including in 4(c) above
and Section 12 below), (i) prior to the Exercise Date, the Holder shall not be entitled to receive dividends, nor shall
anything contained in this Warrant Certificate be construed to confer upon the Holder, as such, any of the rights of a shareholder of
the Company or any right to receive dividends or subscription rights, and (ii) prior to the registration of the Holder in the share
register of the Company with respect to the Warrant Shares to which the Holder is then entitled to receive upon the due exercise of this
Warrant Certificate, the Holder shall not be entitled to vote, nor shall anything contained in this Warrant Certificate be construed to
confer upon the Holder, as such, any right to vote, give or withhold consent to any corporate action (whether any reorganization, issue
of shares, reclassification of shares, consolidation, merger, conveyance or otherwise) or receive notice of meetings. In addition, nothing
contained in this Warrant Certificate shall be construed as imposing any liabilities on the Holder to purchase any securities (upon exercise
of this Warrant Certificate or otherwise) or as a shareholder of the Company, whether such liabilities are asserted by the Company or
by creditors of the Company. Notwithstanding this Section 8, the Company shall provide the Holder with copies of the same
notices and other information given to all shareholders of the Company generally, contemporaneously with the giving thereof to such shareholders,
unless such notice or information had been made publicly available on the SEC’s EDGAR system website.
Section 9. Replacement
on Loss; Division and Combination.
(a) Replacement
of Warrant Certificate on Loss. Subject to any further requirements in relation to the cancellation of this Warrant Certificate pursuant
to applicable Laws, upon receipt of evidence reasonably satisfactory to the Company of the loss, theft, destruction or mutilation of this
Warrant Certificate and upon delivery of an indemnity reasonably satisfactory to it (it being understood that a written indemnification
agreement or affidavit of loss of the Holder shall be a sufficient indemnity) and, in case of mutilation, upon surrender of such Warrant
Certificate for cancellation to the Company, the Company at its own expense shall execute and deliver to the Holder, in lieu hereof, a
new Warrant Certificate of like tenor and exercisable for an equivalent number of Warrant Shares as this Warrant Certificate so lost,
stolen, mutilated or destroyed; provided that, in the case of mutilation, no indemnity shall be required if this Warrant Certificate
in identifiable form is surrendered to the Company for cancellation.
(b) Division
and Combination of Warrant Certificate. Subject to compliance with the applicable provisions of this Warrant Certificate as to any
transfer or other assignment which may be involved in such division or combination, this Warrant Certificate may be divided or, following
any such division of this Warrant Certificate, subsequently combined with other Warrant Certificates, upon the surrender of this Warrant
Certificate or Warrant Certificates to the Company at its then principal executive offices, together with a written notice specifying
the names and denominations in which new Warrant Certificates are to be issued, signed by each applicable Holder or its agents or attorneys.
Subject to compliance with the applicable provisions of this Warrant Certificate as to any transfer or assignment which may be involved
in such division or combination, the Company shall at its own expense execute and deliver a new Warrant Certificate or Warrant Certificates
in exchange for this Warrant Certificate or Warrant Certificates so surrendered in accordance with such notice. Such new Warrant Certificate
or Warrant Certificates shall be of like tenor to the surrendered Warrant Certificate or Warrant Certificates and shall be exercisable
in the aggregate for an equivalent number of Warrant Shares as this Warrant Certificate or Warrant Certificates so surrendered in accordance
with such notice.
Section 10. Disputes;
No Impairment, etc. The parties hereto agree as follows:
(a)
Disputes. In the event of any dispute which arises between the Holder and the Company (including the Board)
with respect to the calculation or determination of Fair Market Value, VWAP, the adjusted Exercise Price, the number of Warrant
Shares, other Capital Securities, cash or other property issuable upon exercise of this Warrant Certificate, the amount or type of
consideration due to the Holder in connection with any event, transaction or other matter described in Section 4 above
or any other matter involving this Warrant Certificate or the Warrant Shares that is not resolved by the parties after good faith
discussions and efforts to reach resolution, upon the request of the Holder the disputed issue(s) shall be submitted to a firm
of independent investment bankers or public accountants of recognized national standing, which (i) shall be chosen by the
Company and be reasonably satisfactory to the Holder and (ii) shall be completely independent of the Company (an
“Independent Advisor”), for determination, and such determination by the Independent Advisor shall be
binding upon the Company and the Holder with respect to this Warrant, any Warrant Shares issued in connection herewith or the matter
in dispute, as the case may be, absent manifest error. Costs and expenses of the Independent Advisor shall be paid by the
Company.
(b) Equitable
Equivalent. In case any event shall occur as to which the provisions of Section 10(a) above are not strictly applicable
but the failure to make any adjustment would not, in the reasonable, good faith opinion of the Holder, fairly protect the rights and benefits
of the Holder represented by this Warrant Certificate in accordance with the essential intent and principles of Section 10(a),
then, in any such case, at the request of the Holder, the Company shall submit the matter and issues raised by the Holder to an Independent
Advisor, which shall give its opinion upon the adjustment, if any, on a basis consistent with the essential intent and principles established
in Section 10(a), to the extent necessary to preserve, without dilution, the rights and benefits represented by this Warrant
Certificate. Upon receipt of such opinion, the Company will promptly mail a copy thereof to the Holder and shall make the adjustments
described therein, if any. Costs and expenses of the Independent Advisor shall be shared 50/50 by the Company and the Holder.
(c) No
Avoidance. The Company shall not, by way of amendment of any of its Charter or other Organic Documents or through any consolidation,
merger, reorganization, transfer of assets, dissolution, issue or sale of securities or any other voluntary action, avoid or seek to avoid
the observance or performance of any of the terms of this Warrant Certificate, and will at all times in good faith assist in the carrying
out of all such terms.
Section 11. Compliance
with the Securities Act.
(a) Agreement
to Comply with the Securities Act, etc.
(i) Legend.
The Holder, by acceptance of this Warrant Certificate, agrees to comply in all respects with the provisions of this Section 11
and the restrictive legend requirements set forth on the face of this Warrant Certificate and further agrees that it shall not offer,
sell or otherwise dispose of this Warrant Certificate or any Warrant Shares to be issued upon exercise hereof except under circumstances
that will not result in a violation of the Securities Act. Subject to clause (ii) below, this Warrant Certificate and all
Warrant Shares issued upon exercise of this Warrant Certificate (unless registered under the Securities Act) shall be stamped or imprinted
with a legend in substantially the following form:
“THIS WARRANT CERTIFICATE AND THE
SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE
“SECURITIES ACT”), OR QUALIFIED UNDER ANY STATE OR FOREIGN SECURITIES LAWS AND MAY NOT BE OFFERED FOR SALE, SOLD, PLEDGED,
HYPOTHECATED OR OTHERWISE TRANSFERRED OR ASSIGNED UNLESS (I) A REGISTRATION STATEMENT COVERING THE OFFER AND SALE OF SUCH SECURITIES
IS EFFECTIVE UNDER THE SECURITIES ACT AND IS QUALIFIED UNDER APPLICABLE STATE AND FOREIGN LAW OR (II) THE TRANSACTION IS EXEMPT FROM
THE REGISTRATION AND PROSPECTUS DELIVERY REQUIREMENTS UNDER THE SECURITIES ACT AND THE QUALIFICATION REQUIREMENTS UNDER APPLICABLE STATE
AND FOREIGN LAW AND, IN EACH CASE, IF THE COMPANY REQUESTS, AN OPINION SATISFACTORY TO THE COMPANY TO SUCH EFFECT HAS BEEN RENDERED
BY COUNSEL.”
(ii) Removal
of Restrictive Legends. Neither this Warrant Certificate nor any Warrant Shares issuable or deliverable under or in connection with
this Warrant Certificate shall contain any legend restricting the transfer thereof (including the legend set forth above in clause
(i)) in any of the following circumstances: (A) following any sale of this Warrant Certificate or any Warrant Shares issued or
delivered to the Holder under or in connection here with pursuant to Rule 144, (B) if this Warrant Certificate or the Warrant
Shares are, and with respect to clause (i)(2) of Rule 144 will continue to be, eligible for sale under clause (b)(1) of
Rule 144, or (C) if such legend is not required under applicable requirements of the Securities Act (including judicial interpretations
and pronouncements issued by the staff of the SEC) (collectively, the “Unrestricted Conditions”). If any of
the Unrestricted Conditions are met at the time of issuance of the Warrant Shares, to the reasonable satisfaction of the Company’s
counsel, the Warrant Shares shall be issued free of all legends.
(iii) Replacement
Warrant Certificate. The Company agrees that at such time as the Unrestricted Conditions have been satisfied it shall promptly (but
in any event within ten (10) Business Days) following written request from the Holder issue a replacement Warrant Certificate or
replacement Warrant Shares, as the case may be, free of all restrictive legends.
(iv) Sale
of Unlegended Shares. The Holder agrees that the removal of the restrictive legend from this Warrant Certificate and any certificates
representing securities as set forth in Section 11(a)(ii) above is predicated upon the Company’s reliance that
the Holder will sell this Warrant Certificate or any such securities pursuant to either an effective Registration Statement or otherwise
pursuant to the requirements of the Securities Act, including any applicable prospectus delivery requirements, or an exemption therefrom,
and that if such securities are sold pursuant to a Registration Statement, they will be sold in compliance with the plan of distribution
set forth therein.
(b) Representations
of the Holder. In connection with the issuance of this Warrant Certificate, the Holder represents, as of the Issue Date, to the Company
by acceptance of this Warrant Certificate as follows:
(i) The
Holder is an “accredited investor” as defined in Rule 501 of Regulation D promulgated under the Securities Act. The Holder
is acquiring this Warrant Certificate and the Warrant Shares to be issued upon exercise hereof for investment for its own account and
not with a view towards, or for resale in connection with, the public sale or distribution of this Warrant Certificate or the Warrant
Shares, except pursuant to sales registered or exempted under the Securities Act.
(ii) The
Holder understands and acknowledges that this Warrant Certificate and the Warrant Shares to be issued upon exercise hereof are “restricted
securities” under the Securities Act inasmuch as they are being acquired from the Company in a transaction not involving a public
offering and that, under such Laws and applicable regulations, such securities may be resold without registration under the Securities
Act only in certain limited circumstances. In addition, the Holder represents that it is familiar with Rule 144, as presently in
effect, and understands the resale limitations imposed thereby and by the Securities Act.
(iii) The
Holder acknowledges that it can bear the economic and financial risk of its investment for an indefinite period and has such knowledge
and experience in financial or business matters that it is capable of evaluating the merits and risks of the investment in this Warrant
Certificate and the Warrant Shares. The Holder has had an opportunity to ask questions and receive answers from the Company regarding
the terms and conditions of the offering of this Warrant Certificate and the business, properties, prospects and financial condition of
the Company.
Section 12. Pre-Emptive
Rights. In addition to any adjustments pursuant to Section 4 above, if at any time the Company grants, issues, offers
or sells (i) any Common Shares or (ii) any Options, Convertible Securities or rights to purchase shares, warrants, securities
or other property, in each case pro rata to the record holders of Common Shares (the “Pre-emptive Rights”),
then the Holder shall be entitled to (but shall not be obligated to) acquire, upon the same terms applicable to such Pre-emptive Rights,
the aggregate Pre-emptive Rights which the Holder would have acquired if the Holder had held the number of Warrant Shares acquirable upon
complete exercise of this Warrant Certificate immediately before the date on which a record is taken for the grant, issuance, offer or
sale of such Pre-emptive Rights, or, if no such record is taken, the date as of which the record holders of Common Shares are to be determined
for the grant, issue, offer or sale of such Pre-emptive Rights.
Section 13. Notices.
All notices, requests, consents, claims, demands, waivers and other communications hereunder shall be in writing and shall be deemed to
have been given: (i) when delivered by hand (with written confirmation of receipt); (ii) when received by the addressee if sent
by a nationally recognized overnight courier (receipt requested); (iii) on the date sent by e-mail of a PDF document (with confirmation
of transmission) if sent during normal business hours of the recipient, and on the next Business Day if sent after normal business hours
of the recipient, in each case provided that sender did not receive an automated failed delivery notification; or (iv) on the third
day after the date mailed, by certified or registered mail, return receipt requested, postage prepaid. Such communications must be sent
to the respective parties at the addresses indicated below (or at such other address for a party as shall be specified in a notice given
in accordance with this Section 13).
If to the Company: TriSalus
Life Sciences, Inc.
6272 West 91st
Avenue
Westminster, CO 80031
Attn: Sean Murphy
Email: sean.murphy@trisaluslifesci.com
with a copy to (which shall
not qualify as notice to any party hereto):
Cooley LLP
10265 Science Center Drive
San Diego, CA 92121
Attn: Matt Browne; Carlos
Ramirez
Email: mbrowne@cooley.com;
cramirez@cooley.com
If to the Holder:
OrbiMed Royalty &
Credit Opportunities IV Offshore, LP
c/o OrbiMed Advisors LLC
601 Lexington Avenue, 54th
Floor
New York, NY 10022
Attention: Matthew Rizzo;
OrbiMed Credit Report
Email: RizzoM@OrbiMed.com; ROSCreditops@orbimed.com
with a copy to (which shall
not qualify as notice to any party hereto):
Covington & Burling
LLP
The New York Times Building
620 Eighth Avenue
New York, NY 10018
Attention: Peter Schwartz;
Jennifer Uren
Email: pschwartz@cov.com;
juren@cov.com
Section 14.
Cumulative Remedies. Except to the extent expressly provided in Section 10 to the contrary, the rights
and remedies provided in this Warrant Certificate are cumulative and are not exclusive of, and are in addition to and not in
substitution for, any other rights or remedies available under applicable Laws, in equity or otherwise.
Section 15. Entire
Agreement. This Warrant Certificate constitutes the sole and entire agreement of the parties to this Warrant Certificate with respect
to the subject matter contained herein and supersedes all prior and contemporaneous understandings and agreements, both written and oral,
with respect to such subject matter.
Section 16. Successors
and Assigns. This Warrant Certificate and the rights evidenced hereby (including under Section 6) shall be binding upon
and shall inure to the benefit of the parties hereto and the successors of the Company and the successors and permitted assigns of the
Holder. Such successor or permitted assign of the Holder shall be deemed to be the “Holder” for all purposes hereunder.
Section 17. No
Third-Party Beneficiaries. This Warrant Certificate is for the sole benefit of the Company and the Holder and their respective successors
and, in the case of the Holder, permitted assigns, and nothing herein, express or implied, is intended to or shall confer upon any other
Person any legal or equitable right, benefit or remedy of any nature whatsoever, under or by reason of this Warrant Certificate.
Section 18. Headings.
The headings in this Warrant Certificate are for reference only and shall not affect the interpretation of this Warrant Certificate.
Section 19. Amendment
and Modification; Waiver. Except as otherwise provided herein, this Warrant Certificate may only be amended, modified or supplemented
by an agreement in writing signed by each party hereto. No waiver by the Company or the Holder of any of the provisions hereof shall be
effective unless explicitly set forth in writing and signed by the party so waiving. No waiver by any party shall operate or be construed
as a waiver in respect of any failure, breach or default not expressly identified by such written waiver, whether of a similar or different
character, and whether occurring before or after that waiver. No failure to exercise, or delay in exercising, any rights, remedy, power
or privilege arising from this Warrant Certificate shall operate or be construed as a waiver thereof, nor shall any single or partial
exercise of any right, remedy, power or privilege hereunder preclude any other or further exercise thereof or the exercise of any other
right, remedy, power or privilege.
Section 20. Severability.
If any term or provision of this Warrant Certificate is invalid, illegal or unenforceable in any jurisdiction, such invalidity, illegality
or unenforceability shall not affect any other term or provision of this Warrant Certificate or invalidate or render unenforceable such
term or provision in any other jurisdiction.
Section 21. Governing
Law. This Warrant Certificate shall be governed by and construed in accordance with the internal Laws of the State of New York without
effect to any choice or conflict of Laws provision or rule (whether of the State of New York or any other jurisdiction) that would
cause the application of Laws of any jurisdiction other than those of the State of New York.
Section 22.
Submission to Jurisdiction; Waiver of Jury Trial. Except as provided in Section 10:
(a) Any
legal suit, action or proceeding arising out of or based on this Warrant Certificate or the transactions contemplated hereby may be instituted
in the federal courts of the United States or the courts of the State of New York, in each case located in the city and county of New
York. Each party irrevocably submits to the exclusive jurisdiction of such courts in any such suit, action or proceeding. Service of process,
summons, notice or other document by certified or registered mail to such party’s address set forth in Section 13 shall
be effective service of process for any suit, action or other proceeding, and the parties irrevocably and unconditionally waive any objection
to the laying of venue of any suit, action or other proceeding in such courts and irrevocably waive and agree not to plead or claim in
any such court that any such suit, action or proceeding has been brought in an inconvenient forum.
(b) EACH
PARTY ACKNOWLEDGES AND AGREES THAT ANY CONTROVERSY WHICH MAY ARISE UNDER THIS WARRANT CERTIFICATE IS LIKELY TO INVOLVE COMPLICATED
AND DIFFICULT ISSUES, AND THEREFORE EACH SUCH PARTY HEREBY IRREVOCABLY AND UNCONDITIONALLY WAIVES ANY RIGHT SUCH PARTY MAY HAVE TO
A TRIAL BY JURY WITH RESPECT TO ANY LITIGATION DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THIS WARRANT CERTIFICATE. EACH PARTY
CERTIFIES AND ACKNOWLEDGES THAT (i) NO REPRESENTATIVE, AGENT OR ATTORNEY OF THE OTHER PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE,
THAT SUCH OTHER PARTY WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE FOREGOING WAIVER, (ii) SUCH PARTY UNDERSTANDS
AND HAS CONSIDERED THE IMPLICATIONS OF THIS WAIVER, (iii) SUCH PARTY MAKES THIS WAIVER VOLUNTARILY, AND (iv) SUCH PARTY HAS
BEEN INDUCED TO ENTER INTO THIS WARRANT CERTIFICATE AND EACH ANCILLARY AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS
IN THIS SECTION.
Section 23. Counterparts.
This Warrant Certificate may be executed in counterparts, each of which shall be deemed an original, but all of which together shall be
deemed to be one and the same agreement. A signed copy of this Warrant Certificate delivered by facsimile, e-mail or other means of electronic
transmission shall be deemed to have the same legal effect as delivery of an original signed copy of this Warrant Certificate.
Section 24. No
Strict Construction. This Warrant Certificate shall be construed without regard to any presumption or rule requiring construction
or interpretation against the party drafting an instrument or causing any instrument to be drafted.
[SIGNATURE PAGE FOLLOWS]
IN WITNESS WHEREOF, the Company
has duly executed this Warrant Certificate on the Issue Date.
| TRISALUS LIFE SCIENCES, INC. |
| |
| By: |
/s/ Sean Murphy |
| Name: |
Sean Murphy |
| Title: |
Chief Financial Officer |
[Signature Page to Warrant Certificate]
Accepted and agreed,
ORBIMED ROYALTY & CREDIT
OPPORTUNITIES IV OFFSHORE, LP |
|
|
|
|
|
By: |
OrbiMed ROF IV LLC, |
|
|
its General Partner |
|
|
|
|
|
|
By OrbiMed Advisors LLC, |
|
|
|
its Managing Member |
|
By: |
/s/ Matthew Rizzo |
|
|
Name: Matthew Rizzo |
|
|
Title: Member |
|
[Signature Page to Warrant Certificate]
Exhibit A
to Warrant Certificate
FORM OF EXERCISE CERTIFICATE
(To be signed only upon exercise of Warrant Certificate)
To: TriSalus
Life Sciences, Inc.
[Address]
Attention: [●]
The undersigned, as holder
of a right to purchase Warrant Shares (as defined in the Warrant Certificate) of TriSalus Life Sciences, Inc., a Delaware corporation
(the “Company”), pursuant to that certain Warrant Certificate of the Company, dated as of August 15, 2024
(the “Warrant Certificate”), a copy of which is attached to this Exercise Certificate, hereby irrevocably elects
to exercise the purchase right represented by such Warrant Certificate for, and to purchase thereunder, [ ( )]
Warrant Shares of the Company and herewith makes payment with this Exercise Certificate of the Aggregate Exercise Price therefor by the
following method:
The undersigned hereby elects
to make payment of the Aggregate Exercise Price of [ Dollars ($ )]
for ( ) Common Shares using the method described in Section 3(b)(i).
The undersigned hereby elects
to make payment of the Aggregate Exercise Price of [ Dollars ($ )]
for ( ) Common Shares using the method described in Section 3(b)(ii).
The undersigned hereby elects
to make payment of the Aggregate Exercise Price of [ Dollars ($ )]
for ( ) Common Shares using the method described in Section 3(b)(iii).
Unless otherwise defined herein,
capitalized terms have the meanings provided in the Warrant Certificate.
DATED:__________
Exhibit B
to Warrant Certificate
FORM OF ASSIGNMENT
[DATE OF ASSIGNMENT]
THE UNDERSIGNED, [NAME OF
HOLDER], is the holder (in such capacity, the “Holder”) of a warrant certificate issued by TriSalus Life Sciences, Inc.,
a Delaware corporation (the “Warrant Certificate” and the “Company”, respectively),
entitling the Holder to purchase up to [ ] Warrant Shares (as defined in the
Warrant Certificate). Unless otherwise defined, capitalized terms used herein have the meanings ascribed thereto in the Warrant Certificate.
FOR VALUE RECEIVED, the Holder
hereby sells, assigns and transfers to [NAME OF ASSIGNEE] (the “Assignee”) the right to acquire [all Warrant
Shares entitled to be purchased upon exercise of the Warrant Certificate] [
of the Warrant Shares entitled to be purchased upon exercise of the Warrant Certificate]. In furtherance of the foregoing assignment,
the Holder hereby irrevocably instructs the Company to (i) memorialize such assignment on the Warrant Register as required pursuant
to Section 5 of the Warrant Certificate, and (ii) pursuant to Section 7 of the Warrant Certificate, execute
and deliver to the Assignee [and the Holder][a new Warrant Certificate][new Warrant Certificates] reflecting the foregoing assignment
([each] a “Substitute Warrant Certificate”).
The Assignee acknowledges
and agrees that its Substitute Warrant Certificate and the Warrant Shares to be issued upon exercise thereof are being acquired for investment
and that the Assignee will not offer, sell or otherwise dispose of its Substitute Warrant Certificate or any Warrant Shares to be issued
upon exercise or conversion thereof except under circumstances which will not result in a violation of the Securities Act or any applicable
state securities laws. The Assignee represents and warrants for the benefit of the Company that the Assignee is an “accredited investor”
within the meaning of Rule 501 of Regulation D promulgated under the Securities Act.
To the extent required pursuant
to Section 11(a) of the Warrant Certificate, the Assignee acknowledges and agrees that a restrictive legend shall be
applied to the Assignee’s Substitute Warrant Certificate and the Warrant Shares issuable upon exercise of such certificate substantially
consistent with the legend set forth in Section 11(a)(i).
[SIGNATURE PAGE FOLLOWS]
IN WITNESS WHEREOF, the parties
hereto agree as set forth above as of the date first written above.
Accepted and agreed,
[NAME OF ASSIGNEE] | |
| | |
By | | |
| Name: | |
| Title: | |
Exhibit 5.1
Carlos A. Ramirez |
|
+1 858 550 6157 |
|
cramirez@cooley.com |
|
October 29, 2024
TriSalus Life Sciences, Inc.
6272 W. 91st Ave.
Westminster, Colorado 80031
Ladies and Gentlemen:
We have acted as counsel to TriSalus Life Sciences, Inc.,
a Delaware corporation (the “Company”) (f/k/a MedTech Acquisition Corporation), in connection with the filing
by the Company of a Registration Statement on Form S-3 (the “Registration Statement”) with the Securities
and Exchange Commission (the “Commission”) under the Securities Act of 1933, as amended (the “Securities
Act”), including a related prospectus included in the Registration Statement (the “Prospectus”),
covering the registration for resale of up to 10,587,582 shares (the “Shares”) of the Company’s common
stock, $0.0001 par value per share. The Shares were issued pursuant to the Agreement and Plan of Merger, dated as of November 11,
2022, as amended on April 4, 2023, May 13, 2023 and July 5, 2023 (the “Merger Agreement”), by
and among the Company, MTAC Merger Sub, Inc. and TriSalus Operating Life Sciences, Inc.
In connection with this opinion, we have examined
and relied upon the Registration Statement, the Prospectus, the Merger Agreement, the Company’s certificate of incorporation and
bylaws, each as currently in effect, and such other records, documents, opinions, certificates, memoranda and instruments as in our judgment
are necessary or appropriate to enable us to render the opinion expressed below. We have assumed the genuineness of all signatures, the
authenticity of all documents submitted to us as originals, the conformity to originals of all documents submitted to us as copies, the
accuracy, completeness and authenticity of certificates of public officials and the due authorization, execution and delivery of all
documents by all persons other than the Company where authorization, execution and delivery are prerequisites to the effectiveness thereof.
As to certain factual matters, we have relied upon a certificate of an officer of the Company and have not independently verified such
matters.
Our opinion is expressed only with respect to
the General Corporation Law of the State of Delaware. We express no opinion to the extent that any other laws are applicable to the subject
matter hereof and express no opinion and provide no assurance as to compliance with any federal or state antifraud law, rule or
regulation relating to securities or to the sale or issuance thereof.
On the basis of the foregoing, and in reliance
thereon, we are of the opinion that the Shares are validly issued, fully paid and nonassessable.
Our opinion is limited to the matters expressly
set forth in this letter, and no opinion has been or should be implied, or may be inferred, beyond the matters expressly stated. This
opinion speaks only as to law and facts in effect or existing as of the date hereof, and we have no obligation or responsibility to update
or supplement this letter to reflect any facts or circumstances that may hereafter come to our attention or any changes in law that may
hereafter occur.
We hereby consent to the reference to our firm
under the caption “Legal Matters” in the Prospectus and to the filing of this opinion as an exhibit to the Registration Statement.
In giving such consents, we do not thereby admit that we are in the category of persons whose consent is required under Section 7
of the Securities Act or the rules and regulations of the Commission thereunder.
Very truly yours,
Cooley
LLP
By: | /s/ Carlos A. Ramirez | |
| Carlos A. Ramirez | |
Cooley LLP 10265 Science Center Drive San Diego,
CA 92121-1117
t: (858) 550-6000 f: (858) 550-6420 cooley.com
Exhibit 23.1
|
|
|
KPMG LLP
Suite 800 1225 17th Street Denver, CO 80202-5598 |
Consent of Independent Registered Public
Accounting Firm
We consent to
the use of our report dated April 11, 2024, with respect to the consolidated financial statements of TriSalus Life Sciences,
Inc., included herein, and to the reference to our firm under the heading "Experts" in the prospectus.
/s/
KPMG LLP
Denver, Colorado
October 29, 2024
| KPMG LLP, a Delaware limited liability partnership and a member firm of
the KPMG global organization of independent member firms affiliated with
KPMG International Limited, a private English company limited by guarantee. | |
Exhibit 107
Calculation of Filing Fee Tables
S-3
(Form Type)
TriSalus Life Sciences, Inc.
(Exact Name of Registrant as Specified in its Charter)
Table 1: Newly Registered
|
|
|
|
|
|
|
|
|
|
Security
Type |
Security
Class
Title |
Fee
Calculation
Rule |
Amount
Registered(1) |
Proposed
Maximum
Offering
Price Per
Share |
Maximum
Aggregate
Offering
Price |
Fee Rate |
Amount of
Registration
Fee |
Newly Registered Securities |
Fees to
Be Paid |
Equity |
Common Stock,
par value
$0.0001 per
share |
457(c) |
10,587,582(2) |
$4.08(3) |
$43,197,334.60 |
$0.00015310 |
$6,613.51 |
|
Total Offering Amounts |
|
$43,197,334.60 |
|
$6,613.51 |
|
Total Fees Previously Paid |
|
|
|
— |
|
Total Fee Offsets |
|
|
|
— |
|
Net Fees Due |
|
|
|
$6,613.51 |
(1) |
Includes an indeterminable number of additional securities that, pursuant to Rule 416 under the Securities Act of 1933, as amended, may be issued to prevent dilution from stock splits, stock dividends or similar transactions that could affect the Common Stock to be offered by the selling securityholder. |
(2) |
Represents 10,587,582 shares of Common Stock registered for resale by the selling securityholders identified in this registration statement. |
(3) |
Estimated solely for the purpose of computing the amount of the registration fee pursuant to Rule 457(c) under the Securities Act of 1933, as amended, based on the average of the high and low sales price of the Registrant’s shares of Common Stock as reported on the Nasdaq Stock Market on October 24, 2024. |
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