Applied Imaging Announces Reverse Stock Split SAN JOSE, Calif., May 19 /PRNewswire-FirstCall/ -- Applied Imaging Corp. (NASDAQ:AICX) today announced that on May 19, 2005, it obtained stockholder approval to effect a proposed reverse stock split at the Company's annual meeting of stockholders, and that its board of directors then implemented a 1-for-4 reverse stock split. Pursuant to the stock split, each holder of Applied Imaging common stock will receive one newly-issued share for each four shares held as of May 19, 2005. Applied Imaging's transfer agent, Wells Fargo Shareowner Services of St. Paul, Minnesota, will act as the administrator for the reverse stock split. Applied Imaging's common stock will begin trading on the Nasdaq SmallCap Market on a reverse split basis as of the opening of trading on May 20, 2005. For a period of 20 trading days, shares of Applied Imaging's common stock will trade under the ticker "AICXD." After 20 trading days, trading is expected to resume under the ticker "AICX." About Applied Imaging Applied Imaging Corp., based in San Jose, California, is the leading supplier of automated imaging and image analysis systems for the detection and characterization of chromosomes and molecular markers in genetics and pathology laboratories. The Company develops, manufactures and markets a range of scanning and image analysis systems for both conventional (brightfield) and fluorescent microscopic analysis of cellular and tissue specimens. Products are sold to hospital laboratories, cancer centers, prenatal clinics and research institutions for both research and clinical purposes. The Company has installed over 3,500 of its systems in over 1000 laboratories in more than 60 countries around the world. Beyond its core business, through its wholly-owned subsidiary, CTC, Inc., the Company is also developing a system for the detection, quantification and characterization of tumor cells in the blood of cancer patients. More information about Applied Imaging can be found at http://www.aicorp.com/. Code: AICXG Contacts: For More Information: CCG Investor Relations Crocker Coulson, President 15300 Ventura Boulevard, Suite 303 Sherman Oaks, CA 91403 (818) 789-0100 Applied Imaging Corp. Terry Griffin, Chief Financial Officer 120 Baytech Drive, San Jose, CA 95134 (408) 719-6400 DATASOURCE: Applied Imaging Corp. CONTACT: Crocker Coulson, President of CCG Investor Relations, +1-818-789-0100, , for Applied Imaging Corp.; or Terry Griffin, Chief Financial Officer of Applied Imaging Corp., +1-408-719-6400, Web site: http://www.aicorp.com/

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