PTP Profile Thera.

RNS Number:2741B
Profile Therapeutics PLC
27 July 2004


Letter to Profile Therapeutics plc


SECTION 198 COMPANIES ACT 1985

We, The Royal Bank of Scotland Group plc, for ourselves and on behalf of:

The Royal Bank of Scotland plc
National Westminster Bank plc
and NatWest Ventures Investments Ltd

write to advise you pursuant to Section 198 of the Companies Act 1985 (the Act)
that:

1.  This notification relates to the ordinary 2p share capital of Profile 
    Therapeutics plc.

2.  The Royal Bank of Scotland Group plc, The Royal Bank of Scotland plc, 
    National Westminster Bank plc and NatWest Ventures Investments Ltd no
    longer have a notifiable interest (within the meaning of Section 199(2) of
    the Act) in shares comprised in the share capital.


Letter from  Royal Bank of Scotland Group plc



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END
HOLUBVVRSRRBUAR

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