PTP Profile Thera.

RNS Number:8194W
Profile Therapeutics PLC
23 March 2004



The Holding(s) in Company announcement released on 22/3/04 at 09:12 under 
RNS No 7655W contained a transposition error.

It should read

BNY (OCS) Nominees 
Limited a/c 3i plc      3i Group plc                 8,072,267    

BNY (OCS) Nominees 
Limited a/c 3iBio         3i Bioscience 
                          Investment Trust plc*        1,444,117  

and not


BNY (OCS) Nominees 
Limited a/c 3i plc        3i Group plc1,444,117   

BNY (OCS) Nominees 
Limited a/c 3iBio         3i Bioscience 
                          Investment Trust plc*        8,072,267   



All other details remain unchanged.

The full amended text is shown below.



Letter to: Profile Therapeutics PLC


Companies Act 1985 ("the Act") - Disclosure of Interests In Shares

In accordance with sections 198 - 202 of the Act (as amended by the Companies 
Act 1989 and the Disclosure of Interests in Shares (Amendment) Regulations 1993) 
we hereby notify you of a change in the interest of 3i Group plc in the share 
capital of your company which is notifiable under the provisions of the Act and 
which is detailed below:

Registered Holder         Beneficial Owner      Ordinary shares of 2p each

BNY (OCS) Nominees 
Limited a/c 3i plc        3i Group plc                 8,072,267    

BNY (OCS) Nominees 
Limited a/c 3iBio         3i Bioscience 
                          Investment Trust plc*        1,444,117  


                          Total interest of 3i 
                          Group plc                    9,516,384

3i Holdings plc, 3i plc and 3i Investments plc are also interested in the shares 
beneficially owned by 3i Bioscience Investment Trust plc.


From: 3i Group PLC



                      This information is provided by RNS
            The company news service from the London Stock Exchange
END
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