TIDMCRYO 
 
RNS Number : 9220I 
Cryo-Save Group NV 
22 March 2010 
 

22 March 2010 
 
Cryo-Save Group N.V. 
 
Revenue up 30%, underlying profit up 38% 
 
Cryo-Save Group N.V. (AIM/Euronext: CRYO, "Cryo-Save", or "the Group"), Europe's 
leading adult stem cell storage bank, has published its full year results for 
the year to 31 December 2009. 
 
Financial highlights 
·      Revenue up 30% to EUR38.4 million (2008: EUR29.5 million) 
·      Gross margin increased to 71% (2008: 69%) 
·      Underlying* EBITA up 76% to EUR6.0 million (2008: EUR3.4 million) 
·      Underlying* profit before taxation up 38% to EUR5.4 million (2008: EUR3.9 
million) 
·      Underlying* earnings per share up 34% to 48.4 euro cents (2008: 36.0 euro 
cents) 
·      Proposed dividend of 6 euro cent per share (2008: 5 euro cent) 
·      Net cash from operating activities EUR4.8 million (2008: EUR2.0 million) 
·      Operating profit EUR2.3 million (2008: EUR2.3 million) 
·      Profit before taxation EUR1.8 million (2008: EUR2.9 million) 
·      Net profit EUR1.4 million (2008: EUR2.6 million) 
·      Earnings per share 14.6 euro cents (2008: 27.3 euro cents) 
 
Operational highlights 
·      Leading market position maintained or strengthened in all key markets 
·      Number of new samples stored up 11% to 27,900 (2008: 25,200) 
·      Over 120,000 samples stored  by the end of 2009 
·      Several samples released for stem cell transplantation and blood testing 
·      Strong organic growth in Europe 
 
Outlook 2010 
·      Combined service of cord blood and cord tissue storage expected to result 
in higher revenue 
·      Launch of the new service Cryo-Lip in first half of 2010 
·      Higher operational gearing due to restructuring and cost savings in 2009 
 
*Underlying results are adjusted for amortisation of identified intangible 
assets, write down of the receivable from the Group's associate, Euronext 
listing costs and restructuring costs. 
 
Marc Waeterschoot, Chief Executive, commented: 
 
"2009 was a very strong year for us.  Not only did we see good returns and 
benefits from our investment programme over the previous few years, but we 
continued to invest in developing new products and moving into new countries. 
Hence our proposed 20% increase in dividend. 
 
"The strategic rationale for stem cell storage continues to strengthen as 
medical advances widen the potential usages for stored cells, whilst our 
geographical reach, product range and operational gearing, are enabling us to 
maintain our rapid growth." 
 
Enquiries: 
 
+------------------------------------------+------------------+ 
| Cryo-Save Group                          | + 31 (0) 575 548 | 
|                                          |              998 | 
+------------------------------------------+------------------+ 
| Marc Waeterschoot, Chief Executive       |                  | 
| Arnoud van Tulder, Chief Financial       |                  | 
| Officer                                  |                  | 
+------------------------------------------+------------------+ 
|                                          |                  | 
+------------------------------------------+------------------+ 
| Daniel Stewart & Company plc             | + 44 (0) 20 7776 | 
|                                          |             6550 | 
+------------------------------------------+------------------+ 
| Simon Leathers/ Emma Earl                |                  | 
+------------------------------------------+------------------+ 
|                                          |                  | 
+------------------------------------------+------------------+ 
| College Hill (UK)                        | + 44 (0) 20 7457 | 
|                                          |             2020 | 
+------------------------------------------+------------------+ 
| Adrian Duffield/Rozi Morris              |                  | 
+------------------------------------------+------------------+ 
|                                          |                  | 
+------------------------------------------+------------------+ 
| SPJ Financiële Communicatie Amstelveen   |        +31 (0)20 | 
| (Netherlands)                            |          6478181 | 
+------------------------------------------+------------------+ 
| Kees Jongsma/Leon Melens                 |                  | 
+------------------------------------------+------------------+ 
 
 
About Cryo-Save 
 
With more than 120,000 samples saved, Cryo-Save is the leading stem cell bank in 
Europe and one of the fastest growing in the world.  Driven by its international 
business strategy, Cryo-Save is now represented in 38 countries on three 
continents and has state-of-the-art processing facilities in Belgium, Germany, 
Dubai, India and France (under construction). 
 
 
Highlights 
 
In March 2009, Cryo-Save announced that it had 100,000 stem cell samples under 
storage, underpinning its market leading position in Europe. Quarter on quarter 
the Group achieved a storage record, resulting in slightly over 120,000 samples 
stored as at 31 December 2009. 
 
During 2009 Cryo-Save completed the development of its new state-of-the art 
processing and storage facility in Niel, Belgium. This facility was self-funded 
and has been operational since the beginning of September 2009. Cryo-Save 
completed the sale and lease back of the Niel facility in April 2009 for EUR4.3 
million. 
 
In July 2009, Cryo-Save signed an exclusive distribution agreement with a 
leading pan European medical diagnostic labs network. This has further 
strengthened the Group's leading position. 
 
Also in July 2009, Cryo-Save acquired Salus Futura in Italy for an initial 
consideration of EUR0.4 million in cash and a deferred performance related 
payment. Salus Futura is an Italian stem cell storage marketing and distribution 
company which concentrates primarily on customer acquisition through diagnostic 
centres and private clinics. 
 
Since 22 October 2009, the Group has been listed on NYSE Euronext Amsterdam, in 
addition to its listing on the London Stock Exchange Alternative Investment 
Market (AIM). 
 
Financial review 
 
Revenue 
 
Group revenue increased sharply to EUR38.4 million (2008: EUR29.5 million), up 30% 
as a result of a combination of the increase in storage volumes, the full year 
impact of acquisitions, especially Crio Cord in Spain and Cryo-Save Balcanica, 
and the full year impact of price increases from late 2008. 
 
Revenue includes the impact of the change of discount rate on the net present 
value of deferred revenue amounting to EUR0.2 million (2008: EUR0.2 million). 
 
Overall, total storage of new samples grew 11% to 27,900 samples, in comparison 
to the 25,200 new samples stored in 2008. All of this growth was organic and 
mainly achieved in Europe and Asia. 
 
Total sales volume for the second half of the year grew 10% to 14,600 new 
samples (2HY 2008: 12,700) in comparison to the 13,300 new samples stored in the 
first half of 2009 (1HY 2008: 12,500). 
 
Geographical breakdown of revenue 
 
+-----------------------------------------------+------+--------------+ 
| EUR in millions                                 | 2009 |         2008 | 
+-----------------------------------------------+------+--------------+ 
| Europe                                        | 36.5 |         28.5 | 
+-----------------------------------------------+------+--------------+ 
| Asia                                          |  1.2 |          0.4 | 
+-----------------------------------------------+------+--------------+ 
| Africa                                        |  0.7 |          0.6 | 
+-----------------------------------------------+------+--------------+ 
| Total                                         | 38.4 |         29.5 | 
+-----------------------------------------------+------+--------------+ 
 
 
Europe remains Cryo-Save's main market, underpinning its leading position in 
Europe. Revenue growth in Europe was a result of a combination of higher sales 
volume, the introduction of the combined service storing stem cells from 
umbilical cord blood as well as the cord tissue, and the full year impact from 
2008 acquisitions. 
 
The growth in Asia is all organic mainly from the Indian business. 
 
Gross profit and gross margin 
Gross profit increased by 35% to EUR27.2 million (2008: EUR20.2 million). The gross 
margin increased to 71% (2008: 69%). The impact from acquisitions, the late 2008 
price increase, and cost savings particularly in terms of logistics, were the 
main drivers for the margin improvement. 
 
Operating expenses 
Reported operating expenses, excluding depreciation and amortisation, amounted 
to EUR22.6 million (2008: EUR16.3 million), but included EUR2.4 million exceptional 
non-recurring expenses, resulting in underlying operating expenses of EUR20.2 
million (2008: EUR16.3 million). The increase was mainly caused by the impact from 
the 2008 acquisitions and the additional investments in the Indian and French 
operations, partly offset by cost savings. 
In 2009, Cryo-Save continued to invest in its Indian operation, and in France. 
The operating expenses of the Group's Indian operations were EUR0.5 million (2008: 
EUR0.4 million), and the operating expenses of the French operations were EUR1.1 
million higher (2008: EUR0.2 million). 
 
Underlying marketing and sales expenses amounted to EUR10.2 million (2008: EUR7.8 
million). Reported marketing and sales expenses increased to EUR10.6 million 
(2008: EUR7.8 million), including EUR0.4 million of exceptional non-recurring 
restructuring expenses of the Italian subsidiary as a result of the integration 
of the Italian subsidiary and the acquired entity Salus Futura. 
Research and development costs of EUR0.4 million (2008: EUR0.1 million) relate to: 
the new services added to the Cryo-Cord service in June 2008 (the collection, 
processing, preservation and storage of the umbilical cord tissue containing 
MSCs); the development of Cryo-Lip, a new service of the collection, processing, 
preservation and storage of fat tissue containing MSCs obtained via liposuction 
from adults (proposed launch in the first half year of 2010) and; funding 
applied research. 
Underlying general and administrative expenses, excluding the exceptional 
non-recurring write down of the receivables from the Arabian associate (EUR1.0 
million), the non-recurring Euronext listing costs (EUR1.0 million) and 
depreciation and amortisation amounted EUR9.6 million (2008: EUR8.3 million). 
Reported general and administrative expenses excluding depreciation and 
amortisation amounted EUR11.6 million (2008: EUR8.3 million). 
Cryo-Save's associate Cryo-Save Arabia, which operates in the United Arab 
Emirates, saw a significant decrease in sales during 2009. As a result, the 
Group wrote down EUR1.0 million of receivables due from Cryo-Save Arabia. This 
relates to non-cash fees of EUR0.5 million for services regarding the construction 
of the processing and storage facility, a non-cash royalty fee of EUR0.2 million 
for samples processed and stored in Dubai, and a fee of EUR0.3 million for samples 
processed and stored in the Belgium processing and storage facility from UAE 
customers. The receivables comprise EUR0.5 million relating to 2007, EUR0.3 million 
to 2008 and EUR0.2 million to 2009. 
 
The non-recurring Euronext listing costs mainly relate to advisers fees. 
 
EBITA and operating profit 
 
Underlying Earnings Before Interest, Taxation and Amortisation of identified 
intangible assets (EBITA before Arabia write down, Euronext listing costs and 
Italian restructuring costs) increased significantly by 76% to EUR6.0 million 
(2008: EUR3.4 million), as a result of higher gross profit and tight cost control, 
partly offset by higher investments in India and France, and higher 
depreciation. This EBITA improvement reflects the Group's high operational 
gearing.  Reported EBITA was EUR3.6 million (2008: EUR3.4 million). 
 
Underlying operating profit was up 76% to EUR6.0 million (2008: EUR3.4 million). 
Reported operating profit was EUR2.3 million (2008: EUR2.3 million). 
 
Depreciation was EUR1.0 million (2008: EUR0.6 million), and amortisation EUR1.3 
million (2008: EUR1.0 million). The increase of depreciation is mainly caused by 
the start of depreciating the Belgium and French building including its new 
equipment. Amortisation mainly increased due to the identified intangible assets 
of Salus Futura and the start of amortisation of the capitalised costs of 
Cryo-CordPlus and the Group's new website. 
 
Net finance costs/income 
 
Net finance costs of EUR0.5 million included EUR0.3 million of non-cash IFRS 
expenses from unwinding discounted earn out liabilities. 
The change compared to the net finance income of EUR0.6 million in 2008 was mainly 
caused by the high interest income in the first half year of 2008 on cash 
deposits which were spent on acquisitions in the second half of 2008. 
 
Profit before taxation 
 
Underlying profit before taxation was up 38% to EUR5.4 million (2008: EUR3.9 
million). Reported profit before taxation was EUR1.8 million (2008: EUR2.9 million). 
 
Taxation 
 
The underlying effective tax rate (ETR) amounted 17% (2008: 14%), the reported 
ETR 24%. The ETR increased compared to 2008 mainly due to losses carried forward 
that were not capitalised due to the uncertainty of future profits to offset 
these losses. Furthermore, the effective tax rate increased due to increased 
profits in countries with a relatively high tax rate compared to the 
historically low effective tax rate. 
 
Profit for the period 
 
Underlying profit after taxation for 2009 was up 32% to EUR4.5 million (2008: EUR3.4 
million). Reported profit after taxation amounted EUR1.4 million (2008: EUR2.6 
million). 
 
Earnings per share 
 
Underlying earnings per share were up 34% at 48.4 euro cents per share (2008: 
36.0 euro cents). 
 
Reported earnings per share were 14.6 euro cents per share (2008: 27.3 euro 
cents per share, adjusted for the 5:1 Share Consolidation exercised in October 
2009). 
 
Dividend 
 
The Board is recommending a dividend of 6 euro cent per share for the year ended 
31 December 2009, this represents an increase of 20% from the previous year's 
dividend of 5 euro cent per share.  If approved at the Annual General Meeting on 
19 May 2010, the dividend will be paid on 17 June 2010 to shareholders on the 
register at 21 May 2010. The ex-dividend date will be 19 May 2010. 
 
Cash flow 
 
Net cash from operating activities was EUR4.8 million (2008: EUR2.0 million). The 
Group invested EUR4.6 million in property, plant and equipment, mainly related to 
the new processing and storage facility in Niel, Belgium, which was financed by 
the sale and lease back transaction with ING Lease Belgium N.V. of EUR4.3 million. 
 
Strategy 
 
During 2009 the Group delivered on its strategic objectives: organic growth in 
existing markets, geographic growth into new markets, growth by acquisitions and 
development of new services. The Group strengthened or maintained its leading 
market position in all key markets. Cryo-Save will continue to pursue these 
strategic objectives also in 2010 to maintain the rapid growth. 
 
Operating review 
 
Cryo-Save is Europe's leading stem cell bank with a market share of around 50%, 
having stored over 120,000 samples by the year end 2009. The Group is present in 
almost all European countries, by means of its own subsidiary or via a marketing 
and sales partnership. There is no stem cell bank that can match Cryo-Save's 
geographic spread. 
 
In 2009 there have been several new entrants to the market. Despite this, in 
almost all countries the Group maintained or even strengthened its leading 
position. Cryo-Save was the first Company that introduced the storage of cord 
tissue in several European countries. 
 
In 2009 the Group continued its marketing and sales approach concentrating on 
customer acquisition through diagnostic centres and private clinics. Also some 
contracts with leading private insurers that support this service towards their 
clients were renewed. 
 
In Asia, the main market for Cryo-Save is currently India. The Group has 
introduced its services successfully to the market, in several key metropolitan 
cities. The concept of banking umbilical cord blood and the cord tissue is 
rapidly developing across the country but particularly in urban centres. Public 
banking has yet to take off, partly because donation to a public bank is 
hampered by the fact that there is a high human leukocyte antigen (HLA) 
diversity in the country, which makes a perfect HLA match between donor and 
patient difficult to achieve. In slightly over a year Cryo-Save has already 
gained a strong market position. 
 
Applied research & development of new services 
 
In the last four months of 2009, after a long period of development and 
validation, the Group rolled out its new combined service of storing stem cells 
from both the cord blood and umbilical cord itself, in the largest markets 
Hungary, Italy and Spain. The uptake by customers has been ahead of 
expectations. 
 
The development and validation of the new Cryo-Lip service, which is scheduled 
to be launched during the first half year of 2010, progressed well in 2009. 
Cryo-Lip involves the collection and storage of fat tissue containing 
mesenchymal stem cells obtained via liposuction from adults. In the first half 
year of 2009 the Group undertook a detailed validation of the collection and 
processing procedures.  During the second half of 2009 Cryo-Save further 
optimised all of the procedures, including the devices to be used, in order to 
improve the quality and lower the cost of the service. A detailed business plan 
to introduce Cryo-Lip to the market was developed and first contacts with 
Europe's premium cosmetic and plastic surgery clinics were made. These clinics 
will be the primary point of contact and sale for this innovative new service 
offering. 
 
The three year long CRYSTAL project which was funded by the European 
Commission's 6th Framework programme for Research and Development (FP6), 
completed during 2009. In 2007 Cryo-Save was selected to work alongside five 
European universities, two SMEs and one research institute to collaborate under 
the auspices of the University of Cologne, in a major project to develop tools 
and procedures to enable cryo-preservation of different types of stem cells in 
order to generate sufficient amounts of high-quality stem cells for therapeutic 
use. The objectives of the research revolved around three axes: preparation and 
cultivation methods, preservation methods, and validation methods. As a result 
of its participation in this project Cryo-Save is now at the leading edge of 
freezing cells for therapeutic use. 
 
Following the completion of CRYSTAL, the European Commission Framework 7 has now 
funded and launched the HYPERLAB project. Cryo-Save is one of eight institutions 
which will collaborate under the coordination of Prof. Dr. Heiko Zimmermann. 
This three years project, which was launched on 1 February 2010, aims to develop 
new and improved culture methods, media, and protocols for stem cell cultivation 
and differentiation. 
Cryo-Save is the only cord blood bank in Europe to take part in these advanced 
projects - reflecting both its market leading position and its commitment to the 
development of stem cell research. 
 
Delisting from London Stock Exchange/AIM 
 
The Group is currently listed on the NYSE Euronext Amsterdam Stock Exchange and 
the non-regulated London Stock Exchange AIM market. Following examination of the 
Company's shareholder base, the costs involved in maintaining its listings, and 
shareholder liquidity, the Board has decided to delist from AIM in order to 
increase liquidity of its shares on NYSE Euronext Amsterdam Stock Exchange and 
to save the costs from two listings. A further announcement will be made in due 
course outlining the delisting process and the implications for shareholders. 
 
Current trading and outlook 
 
In the second half of 2009 Cryo-Save strengthened its strategic position and 
operational capabilities. The combined service of cord blood and cord tissue 
storage has been well accepted by the market and is expected to result in higher 
revenue in 2010. In the first half of 2010 the new service Cryo-Lip is planned 
for launch whilst restructurings and cost savings in 2009 will also result in a 
higher operational gearing in 2010. 
 
With the Group's increased geographic spread, and new services, the Board is 
confident that Cryo-Save will continue to maintain its rapid growth. 
 
 
Consolidated statement of income 
in thousands of euros 
 
+--------------------------------------------------+-------+-----------+----------+ 
|                                                  |Notes  |      2009 |     2008 | 
+--------------------------------------------------+-------+-----------+----------+ 
|                                                  |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| Revenue                                          |  9    |    38,391 |   29,485 | 
+--------------------------------------------------+-------+-----------+----------+ 
| Cost of sales                                    |       |  (11,168) |  (9,278) | 
+--------------------------------------------------+-------+-----------+----------+ 
| Gross profit                                     |       |    27,223 |   20,207 | 
+--------------------------------------------------+-------+-----------+----------+ 
|                                                  |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| Marketing and sales expenses                     |  10   |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| - Other marketing and sales expenses             |       |    10,147 |    7,817 | 
+--------------------------------------------------+-------+-----------+----------+ 
| - Non-recurring restructuring expenses           |       |       421 |        - | 
+--------------------------------------------------+-------+-----------+----------+ 
| Research and development expenses                |  11   |       403 |       97 | 
+--------------------------------------------------+-------+-----------+----------+ 
| General and administrative expenses              |  12   |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| - Other general and administrative expenses      |       |    11,945 |    9,986 | 
+--------------------------------------------------+-------+-----------+----------+ 
| - Non-recurring write-down on equity accounted   |       |     1,027 |        - | 
| investees                                        |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| - Non-recurring listing expenses                 |       |       952 |        - | 
+--------------------------------------------------+-------+-----------+----------+ 
| Total operating expenses                         |       |    24,895 |   17,900 | 
+--------------------------------------------------+-------+-----------+----------+ 
| Operating profit                                 |       |     2,328 |    2,307 | 
+--------------------------------------------------+-------+-----------+----------+ 
|                                                  |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| Finance income                                   |  15   |       118 |      988 | 
+--------------------------------------------------+-------+-----------+----------+ 
| Finance costs                                    |  16   |     (663) |    (434) | 
+--------------------------------------------------+-------+-----------+----------+ 
| Net finance (costs)/income                       |       |     (545) |      554 | 
+--------------------------------------------------+-------+-----------+----------+ 
|                                                  |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| Results relating to equity-accounted investees   |       |         0 |        0 | 
+--------------------------------------------------+-------+-----------+----------+ 
| Profit before taxation                           |       |     1,783 |    2,861 | 
+--------------------------------------------------+-------+-----------+----------+ 
|                                                  |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
|                                                  |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| Income tax expense                               |  17   |       431 |      293 | 
+--------------------------------------------------+-------+-----------+----------+ 
| Profit for the year                              |       |     1,352 |    2,568 | 
+--------------------------------------------------+-------+-----------+----------+ 
|                                                  |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| Attributable to:                                 |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| - Equity holders of the Company                  |       |     1,352 |    2,568 | 
+--------------------------------------------------+-------+-----------+----------+ 
| - Non-controlling interest                       |       |         - |        - | 
+--------------------------------------------------+-------+-----------+----------+ 
| Profit for the year                              |       |     1,352 |    2,568 | 
+--------------------------------------------------+-------+-----------+----------+ 
|                                                  |       |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| Earnings per share (in euro cents)               |  18   |           |          | 
+--------------------------------------------------+-------+-----------+----------+ 
| - Basic*                                         |       |      14.6 |     27.3 | 
+--------------------------------------------------+-------+-----------+----------+ 
| - Diluted*                                       |       |      14.6 |     27.3 | 
+--------------------------------------------------+-------+-----------+----------+ 
 
* The comparative figures have been restated for the 5:1 share consolidation. 
 
 
Consolidated statement of comprehensive income 
in thousands of euros 
 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |      2009 |     2008 | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
| Profit for the year                              |      |     1,352 |    2,568 | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
| Other comprehensive income                       |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
| Foreign currency translation differences         |      |     (235) |    (428) | 
+--------------------------------------------------+------+-----------+----------+ 
| Other comprehensive income for the year          |      |     (235) |    (428) | 
+--------------------------------------------------+------+-----------+----------+ 
| Total comprehensive income for the year          |      |     1,117 |    2,140 | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
| Attributable to:                                 |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
| - Equity holders of the Company                  |      |     1,117 |    2,140 | 
+--------------------------------------------------+------+-----------+----------+ 
| - Non-controlling interest                       |      |         - |        - | 
+--------------------------------------------------+------+-----------+----------+ 
| Total comprehensive income for the year          |      |     1,117 |    2,140 | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
|                                                  |      |           |          | 
+--------------------------------------------------+------+-----------+----------+ 
 
 
Consolidated statement of financial position 
in thousands of euros 
at 31 December 
 
+--------------------------------------------------+-------+----------+----------+ 
|                                                  |Notes  |     2009 |     2008 | 
+--------------------------------------------------+-------+----------+----------+ 
| Assets                                           |       |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Intangible assets                                |  19   |   35,366 |   37,438 | 
+--------------------------------------------------+-------+----------+----------+ 
| Property, plant and equipment                    |       |   13,964 |   10,421 | 
+--------------------------------------------------+-------+----------+----------+ 
| Investments in equity accounted investees        |       |        0 |        0 | 
+--------------------------------------------------+-------+----------+----------+ 
| Deferred tax assets                              |       |    1,121 |      640 | 
+--------------------------------------------------+-------+----------+----------+ 
| Trade and other receivables                      |       |    1,054 |    1,304 | 
+--------------------------------------------------+-------+----------+----------+ 
| Total non-current assets                         |       |   51,505 |   49,803 | 
+--------------------------------------------------+-------+----------+----------+ 
|                                                  |       |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Inventories                                      |       |      251 |      287 | 
+--------------------------------------------------+-------+----------+----------+ 
| Trade and other receivables                      |       |    8,907 |    8,156 | 
+--------------------------------------------------+-------+----------+----------+ 
| Current tax assets                               |       |      687 |    1,205 | 
+--------------------------------------------------+-------+----------+----------+ 
| Cash and cash equivalents                        |       |    7,485 |    4,697 | 
+--------------------------------------------------+-------+----------+----------+ 
| Total current assets                             |       |   17,330 |   14,345 | 
+--------------------------------------------------+-------+----------+----------+ 
|                                                  |       |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Total assets                                     |       |   68,835 |   64,148 | 
+--------------------------------------------------+-------+----------+----------+ 
|                                                  |       |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Equity                                           |  20   |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Issued share capital                             |       |      964 |      964 | 
+--------------------------------------------------+-------+----------+----------+ 
| Share premium reserve                            |       |   38,178 |   38,178 | 
+--------------------------------------------------+-------+----------+----------+ 
| Revaluation reserve                              |       |      669 |      769 | 
+--------------------------------------------------+-------+----------+----------+ 
| Legal reserve                                    |       |      134 |      108 | 
+--------------------------------------------------+-------+----------+----------+ 
| Translation reserve                              |       |    (683) |    (448) | 
+--------------------------------------------------+-------+----------+----------+ 
| Treasury shares                                  |       |  (3,664) |  (3,497) | 
+--------------------------------------------------+-------+----------+----------+ 
| Retained earnings                                |       |    8,209 |    6,979 | 
+--------------------------------------------------+-------+----------+----------+ 
| Equity attributable to equity holders of the     |       |   43,807 |   43,053 | 
| Company                                          |       |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Non-controlling interest                         |       |        - |        - | 
+--------------------------------------------------+-------+----------+----------+ 
| Total equity                                     |       |   43,807 |   43,053 | 
+--------------------------------------------------+-------+----------+----------+ 
|                                                  |       |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Liabilities                                      |       |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Borrowings                                       |  21   |    3,795 |      111 | 
+--------------------------------------------------+-------+----------+----------+ 
| Deferred revenue                                 |  22   |    6,090 |    4,885 | 
+--------------------------------------------------+-------+----------+----------+ 
| Deferred considerations                          |  23   |    2,080 |    5,777 | 
+--------------------------------------------------+-------+----------+----------+ 
| Deferred tax liabilities                         |       |    2,656 |    2,827 | 
+--------------------------------------------------+-------+----------+----------+ 
| Other liabilities                                |  23   |       84 |       53 | 
+--------------------------------------------------+-------+----------+----------+ 
| Total non-current liabilities                    |       |   14,705 |   13,653 | 
+--------------------------------------------------+-------+----------+----------+ 
|                                                  |       |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Borrowings                                       |  21   |      180 |       38 | 
+--------------------------------------------------+-------+----------+----------+ 
| Trade and other payables                         |       |    6,533 |    4,193 | 
+--------------------------------------------------+-------+----------+----------+ 
| Deferred revenue                                 |  22   |      471 |      389 | 
+--------------------------------------------------+-------+----------+----------+ 
| Deferred considerations                          |       |    1,264 |      859 | 
+--------------------------------------------------+-------+----------+----------+ 
| Current tax liabilities                          |       |    1,875 |    1,963 | 
+--------------------------------------------------+-------+----------+----------+ 
| Total current liabilities                        |       |   10,323 |    7,442 | 
+--------------------------------------------------+-------+----------+----------+ 
|                                                  |       |          |          | 
+--------------------------------------------------+-------+----------+----------+ 
| Total liabilities                                |       |   25,028 |   21,095 | 
+--------------------------------------------------+-------+----------+----------+ 
| Total equity and liabilities                     |       |   68,835 |   64,148 | 
+--------------------------------------------------+-------+----------+----------+ 
 
 
Consolidated statement of changes in equity 
in thousands of euros 
 
+------------------------+---------+----------+-----------+-----------------+----------+ 
|                        |  Issued | Treasury |     Other | Non-controlling |    Total | 
|                        |         |          |  reserves |        interest |   equity | 
|                        |  share  |   shares |           |                 |          | 
|                        | capital |          |           |                 |          | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| At 1 January 2008      |     964 |    (435) |    42,392 |               - |   42,921 | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
|                        |         |          |           |                 |          | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| Exchange differences   |         |          |           |                 |          | 
| on                     |         |          |           |                 |          | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| translating foreign    |         |          |     (428) |                 |    (428) | 
| operations             |         |          |           |                 |          | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| Other comprehensive    |         |          |     (428) |                 |    (428) | 
| income                 |         |          |           |                 |          | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
|                        |         |          |           |                 |          | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| Profit for the year    |         |          |     2,568 |                 |    2,568 | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| Comprehensive income   |         |          |           |                 |          | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| for the year           |         |          |     2,140 |                 |    2,140 | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
|                        |         |          |           |                 |          | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| Share-based payments   |         |          |       211 |                 |      211 | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| Repurchased shares     |         |  (3,062) |           |                 |  (3,062) | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| Acquisitions           |         |          |       843 |                 |      843 | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
| At 31 December 2008    |    964  |  (3,497) |    45,586 |               - |   43,053 | 
+------------------------+---------+----------+-----------+-----------------+----------+ 
 
 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| Exchange differences   |        | |         |  |        |          |         |          |          | 
| on                     |        | |         |  |        |          |         |          |          | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| translating foreign    |        | |         |  |  (235) |          |         |          |    (235) | 
| operations             |        | |         |  |        |          |         |          |          | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| Other comprehensive    |        | |         |  |  (235) |          |         |          |    (235) | 
| income                 |        | |         |  |        |          |         |          |          | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
|                        |        | |         |  |        |          |         |          |          | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| Profit for the year    |        | |         |  |  1,352 |          |         |          |    1,352 | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| Comprehensive income   |        | |         |  |  1,117 |          |         |        1 |    1,117 | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| for the year           |        | |         |  |        |          |         |          |          | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
|                        |        | |         |  |        |          |         |          |          | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| Share-based payments   |        | |         |  |    266 |          |         |          |      266 | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| Repurchased shares     |        | |   (167) |  |        |          |         |          |    (167) | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| Dividend distributed   |        | |         |  |  (462) |          |         |          |    (462) | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
| At 31 December 2009    |    964 | | (3,664) |  | 46,507 |          |       - |          |   43,807 | 
+------------------------+--------+-+---------+--+--------+----------+---------+----------+----------+ 
 
 
Consolidated statement of cash flows 
in thousands of euros 
 
 
+------------------------------------------------+-----------+----------+ 
|                                                |      2009 |     2008 | 
+------------------------------------------------+-----------+----------+ 
| Cash flows from operating activities           |           |          | 
+------------------------------------------------+-----------+----------+ 
| Profit for the year                            |     1,352 |    2,568 | 
+------------------------------------------------+-----------+----------+ 
| Adjustments for:                               |           |          | 
+------------------------------------------------+-----------+----------+ 
| Income tax expense                             |       431 |      293 | 
+------------------------------------------------+-----------+----------+ 
| Finance costs                                  |       663 |      434 | 
+------------------------------------------------+-----------+----------+ 
| Finance income                                 |     (118) |    (988) | 
+------------------------------------------------+-----------+----------+ 
| Gain on sale of disposals                      |      (16) |     (27) | 
+------------------------------------------------+-----------+----------+ 
| Depreciation and amortization                  |     2,319 |    1,644 | 
+------------------------------------------------+-----------+----------+ 
| Equity settled share-based payments            |       266 |      211 | 
| transactions                                   |           |          | 
+------------------------------------------------+-----------+----------+ 
|                                                |     4,897 |    4,135 | 
+------------------------------------------------+-----------+----------+ 
| Organic movements in working capital           |           |          | 
+------------------------------------------------+-----------+----------+ 
| (Increase)/decrease in (non)current trade and  |     (501) |  (1,105) | 
| other receivables                              |           |          | 
+------------------------------------------------+-----------+----------+ 
| (Increase)/decrease in inventories             |        36 |     (67) | 
+------------------------------------------------+-----------+----------+ 
| (Increase)/decrease in (non)current tax assets |       222 |  (1,024) | 
+------------------------------------------------+-----------+----------+ 
| Increase/(decrease) in (non)current            |     2,263 |      227 | 
| liabilities                                    |           |          | 
+------------------------------------------------+-----------+----------+ 
| Increase/(decrease) in (non)current tax        |     (213) |    (290) | 
| liabilities                                    |           |          | 
+------------------------------------------------+-----------+----------+ 
| Net cash from operations                       |     6,704 |    1,876 | 
+------------------------------------------------+-----------+----------+ 
|                                                |           |          | 
+------------------------------------------------+-----------+----------+ 
| Interest paid                                  |     (370) |    (192) | 
+------------------------------------------------+-----------+----------+ 
| Interest received                              |       118 |      980 | 
+------------------------------------------------+-----------+----------+ 
| Income taxes paid                              |   (1,671) |    (628) | 
+------------------------------------------------+-----------+----------+ 
| Net cash from operating activities             |     4,781 |    2,036 | 
+------------------------------------------------+-----------+----------+ 
|                                                |           |          | 
+------------------------------------------------+-----------+----------+ 
| Cash flows from investing activities           |           |          | 
+------------------------------------------------+-----------+----------+ 
| Net acquisition spending                       |     (428) | (24,445) | 
+------------------------------------------------+-----------+----------+ 
| Purchase of property, plant and equipment      |   (4,644) |  (9,006) | 
+------------------------------------------------+-----------+----------+ 
| Purchase of intangible assets                  |     (217) |    (400) | 
+------------------------------------------------+-----------+----------+ 
| Disposals of non-current assets                |       118 |      123 | 
+------------------------------------------------+-----------+----------+ 
| Net cash (used in)/generated by investing      |   (5,171) | (33,728) | 
| activities                                     |           |          | 
+------------------------------------------------+-----------+----------+ 
|                                                |           |          | 
+------------------------------------------------+-----------+----------+ 
| Cash flows from financing activities           |           |          | 
+------------------------------------------------+-----------+----------+ 
| Repurchase of own shares                       |     (167) |  (3,062) | 
+------------------------------------------------+-----------+----------+ 
| Divided distributed                            |     (462) |        - | 
+------------------------------------------------+-----------+----------+ 
| Redemption of borrowings                       |     (474) |     (15) | 
+------------------------------------------------+-----------+----------+ 
| Proceeds from borrowings                       |     4,300 |       15 | 
+------------------------------------------------+-----------+----------+ 
| Net cash generated by/(used in) financing      |     3,197 |  (3,062) | 
| activities                                     |           |          | 
+------------------------------------------------+-----------+----------+ 
|                                                |           |          | 
+------------------------------------------------+-----------+----------+ 
| Net increase/(decrease) in cash and cash       |     2,807 | (34,754) | 
| equivalents                                    |           |          | 
+------------------------------------------------+-----------+----------+ 
|                                                |           |          | 
+------------------------------------------------+-----------+----------+ 
| Cash and cash equivalents at 1 January         |     4,697 |   39,465 | 
+------------------------------------------------+-----------+----------+ 
| Exchange differences on cash and cash          |      (19) |     (14) | 
| equivalents                                    |           |          | 
+------------------------------------------------+-----------+----------+ 
| Cash and cash equivalents at 31 December       |     7,485 |    4,697 | 
+------------------------------------------------+-----------+----------+ 
 
 
Notes to the consolidated financial information 
 
(in thousands of euro, unless indicated otherwise) 
 
1.  Reporting entity 
 
Cryo-Save Group N.V. ('the Company' or 'the Group') is a limited liability 
company domiciled in The Netherlands. The address of its registered office and 
principal place of business is IJsselkade 8, 7201 HB Zutphen, The Netherlands. 
 
The Group's principal activity is the collection, processing and storage of 
human adult stem cells collected from the umbilical cord blood, and the 
umbilical cord itself, at birth. 
 
2.  Basis of preparation 
 
Statement of compliance 
 
The consolidated financial statements for the year ended 31 December 2009 were 
authorized for issue by the Board of Directors on 19 March 2010. 
 
The consolidated financial statements of the Group have been prepared in 
accordance with International Financial Reporting Standards (IFRS) and 
International Accounting Standards (IAS) prevailing per 31 December 2009, as 
adopted by the International Accounting Standards Board (IASB) and as endorsed 
for use in the European Union by the European Commission as at 31 December 2009, 
and are prepared on a historical cost basis unless stated otherwise. 
 
The full year 2009 financial figures of Cryo-Save Group N.V. included in the 
primary statements in this report are derived from the financial statements 
2009. These financial statements have been authorized for issue. The financial 
statements have not yet been published by law and still have to be adopted by 
the General Meeting of Shareholders. In accordance with section 2:393 BW, KPMG 
Accountants N.V. has issued an unqualified auditors opinion on these financial 
statements, which will be published on 19 April 2010. 
 
3.  Significant accounting policies 
 
New standards and interpretations 
The first time application of the amendments and interpretations that became 
effective for the year ended 31 December 2009, as listed below, did not result 
in substantial changes to the Group's accounting policies: 
 
* Revised IAS 23 Borrowing costs (effective 1 January 2009); 
* Revised IAS 1 Presentation of Financial Statements (effective 1 January 2009); 
* IAS 27 (Revised) Consolidated and Separate Financial Statements (effective 1 
January 2009); 
* IFRS 2 (Amendment) Share-based payments (effective 1 January 2009). 
 
The impact of the above standards changes on the Group's equity and result is 
not material. 
 
IFRS 3 Business Combinations (Revised) (effective 1 July 2009) 
The new standard will become effective for the Group's 2010 financial 
statements. The Group has not opted for earlier application. The following key 
changes within IFRS 3 Business Combinations (Revised) could have a significant 
impact: 
* Contingent purchase considerations initially measured at fair value, whereby 
and re-measurement is recognized via the statement of income. 
* Acquisition-related costs are to be expenses. 
 
The Group opted for early application of IFRS 8 in the consolidated financial 
statements for the year ended 31 December 2008. 
 
For further details on the principle accounting policies of the Group, we refer 
to our website, www.cryo-savegroup.com, Investor Relations. 
 
4.  Change in accounting estimates 
 
In 2009 the Group did not change any accounting estimate. 
 
5.  Use of estimates and judgements 
 
The preparation of the consolidated financial statements requires management to 
make judgments, estimates and assumptions that affect the application of 
accounting policies and the reported amount of assets, liabilities, income and 
expenses. Actual results may differ from these estimates. Estimates and 
underlying assumptions are reviewed on an ongoing basis. Revisions to accounting 
estimates are recognized in the period in which the estimate is revised and in 
any future periods affected. 
 
6.  Seasonality 
 
The operations of the Company are not impacted by seasonal or cyclical purchase 
patterns. 
 
7.  Acquisitions 
 
Italy 
In July 2009, Cryo-Save acquired Salus Futura Ltd, United Kingdom, which holds 
all shares of Salus Futura Srl, Italy ('Salus Futura'), for an initial amount of 
EUR0.4 million payable in cash and a deferred performance related payment, payable 
annually on the achievement of certain goals until 31 May 2012. Salus Futura is 
an Italian stem cell storage marketing and distribution company. Salus Futura 
concentrates primarily on customer acquisition through diagnostic centers and 
private clinics. 
 
The Salus Futura organization was fully integrated into the Cryo-Save Italy 
organization, hence no separate financial information with respect to the 
revenue contribution for the year 2009 and contribution to the 2009 operating 
profit on this acquisition is available. 
 
Breakdown 
 
Total net acquisition spending in 2009 was EUR0.4 million (2008: EUR24.4 million). 
This includes an amount of EUR49,000 relating to costs that are directly 
attributable to the Salus Futura acquisition, such as legal fees and audit fees. 
 
The acquisition during 2009 had the following effects on the assets and 
liabilities of the Group: 
 
+-------------------------------------+----------+-------------+------------+ 
|                                     | Carrying |        Fair | Recognized | 
|                                     |   amount |       value |     values | 
|                                     |          | adjustments |            | 
+-------------------------------------+----------+-------------+------------+ 
| Non-current assets                  |        2 |         100 |        102 | 
+-------------------------------------+----------+-------------+------------+ 
| Current assets                      |      254 |           - |        254 | 
+-------------------------------------+----------+-------------+------------+ 
| Non-current liabilities             |        - |           - |          - | 
+-------------------------------------+----------+-------------+------------+ 
| Current liabilities                 |    (509) |           - |      (509) | 
+-------------------------------------+----------+-------------+------------+ 
| Deferred tax liabilities            |        - |        (26) |       (26) | 
+-------------------------------------+----------+-------------+------------+ 
| Net identifiable assets and         |    (253) |          74 |      (179) | 
| liabilities                         |          |             |            | 
+-------------------------------------+----------+-------------+------------+ 
| Goodwill on acquisitions            |          |             |        628 | 
+-------------------------------------+----------+-------------+------------+ 
| Consideration                       |          |             |        449 | 
+-------------------------------------+----------+-------------+------------+ 
| Cash acquired                       |          |             |         21 | 
+-------------------------------------+----------+-------------+------------+ 
| Deferred considerations             |          |             |          0 | 
+-------------------------------------+----------+-------------+------------+ 
| Net acquisition spending            |          |             |        428 | 
+-------------------------------------+----------+-------------+------------+ 
 
The fair value adjustment of EUR0.1 million related to the identified intangible 
assets regarding contracts with diagnostic centers. With respect to these 
intangible assets, a deferred tax liability was recognized. The goodwill of EUR0.6 
million is mainly attributable to the skills and talent of Salus Futura's 
management and the synergies expected to be achieved from integrating Salus 
Futura into the Group's existing stem cell storage activities. The goodwill was 
allocated to the 'stem cell storage' segment. 
 
8.  Operating segments 
 
Since the acquisition of Output Pharma Services GmbH ('Output') in January 2008, 
the Group identified two operating segments: the extraction and storage of adult 
human stem cells, and other types of products and services. The latter mainly 
consists of Output. 
 
There are no material levels of integration between the two reportable segments. 
The accounting policies of the reportable segments are the same, expect for 
revenue recognition. Information regarding the results of each reportable 
segments is included below. Performance is measured based on EBITA (earnings 
before interest, tax and amortization on identified intangible assets), as 
included in the internal management reports that are reviewed by the Board. 
There are no inter-segment transactions. 
 
Corporate overhead costs were not allocated to the segment 'other', but to the 
segment 'stem cell storage'. 
 
Information about reportable segments 
 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| for the year ended       |         Stem cell |    Other      |        Total        | 
| 31 December              |           storage |               |                     | 
+--------------------------+-------------------+---------------+---------------------+ 
|                          |    2009 |    2008 |  2009 |  2008 |     2009 |     2008 | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Revenue                  |         |         |       |       |          |          | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Segment revenue          |  36,962 |  27,698 | 1,429 | 1,787 |   38,391 |   29,485 | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Other segment            |         |         |       |       |          |          | 
| information              |         |         |       |       |          |          | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| EBITA                    |   3,459 |   3,164 |    92 |   220 |    3,551 |    3,384 | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Finance income           |     110 |     987 |     8 |     1 |      118 |      988 | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Finance expense          |   (663) |   (426) |   (0) |   (8) |    (663) |    (434) | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Depreciation and         | (2,300) | (1,621) |  (19) |  (23) |  (2,319) |  (1,644) | 
| amortization             |         |         |       |       |          |          | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Profit before taxation   |   1,684 |   2,652 |    99 |   209 |    1,783 |    2,861 | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Income tax expense       |     404 |     227 |    27 |    66 |      431 |      293 | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Segment assets           |  68,337 |  63,662 |   498 |   486 |   68,835 |   64,148 | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Segment liabilities      |  24,901 |  20,908 |   127 |   187 |   25,028 |   21,095 | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
| Capital expenditure      |   4,856 |   9,381 |     5 |    25 |    4,861 |    9,406 | 
+--------------------------+---------+---------+-------+-------+----------+----------+ 
 
Revenue from external customers attributed to the Company's country of domicile, 
the Netherlands, amounted to EUR0.3 million (2008: EUR0.3 million). 
 
Geographical information 
 
In presenting information on the basis of geographical information, revenue per 
continent is based on the geographical location of customers. Non-current 
assets, other than financial instruments and deferred tax assets, are based on 
the geographical location of the assets. 
 
+----------------------------+-----+------------+--------+----------+----------+ 
|                            |     | Revenue             | Non-current assets  | 
| for the year ended         |     |                     |                     | 
| 31 December                |     |                     |                     | 
+----------------------------+-----+---------------------+---------------------+ 
|                            |     |       2009 |   2008 |     2009 |     2008 | 
+----------------------------+-----+------------+--------+----------+----------+ 
| Europe                     |     |     36,525 | 28,521 |   48,617 |   47,071 | 
+----------------------------+-----+------------+--------+----------+----------+ 
| Asia                       |     |      1,193 |    420 |      711 |      786 | 
+----------------------------+-----+------------+--------+----------+----------+ 
| Africa                     |     |        673 |    544 |        2 |        2 | 
+----------------------------+-----+------------+--------+----------+----------+ 
| Total                      |     |     38,391 | 29,485 |   49,330 |   47,859 | 
+----------------------------+-----+------------+--------+----------+----------+ 
 
9.  Revenue 
 
+------------------------------------------------------------+----------+----------+ 
|                                                            |     2009 |     2008 | 
+------------------------------------------------------------+----------+----------+ 
| Stem cell extraction and storage                           |   36,962 |   27,698 | 
+------------------------------------------------------------+----------+----------+ 
| Other products and services                                |    1,429 |    1,787 | 
+------------------------------------------------------------+----------+----------+ 
| Total revenue                                              |   38,391 |   29,485 | 
+------------------------------------------------------------+----------+----------+ 
 
Revenue from stem cell extraction and storage include the impact of the change 
of the discount rate on the net present value of deferred revenue amounting to 
EUR0.2 million additional revenue (2008: EUR0.2 million additional revenue). The 
discount rate is consistently based on the 20 years AAA-rated euro area 
government bonds interest rate, which amounted to 4.4% as at 31 December 2009 
(31 December 2008: 4.0%), plus a liquidity premium of 1.0% 
 
10.  Marketing and sales expenses 
 
+------------------------------------------------------------+----------+----------+ 
|                                                            |     2009 |     2008 | 
+------------------------------------------------------------+----------+----------+ 
| Employee benefit expenses                                  |    6,439 |    5,465 | 
+------------------------------------------------------------+----------+----------+ 
| Non-recurring restructuring expenses                       |      421 |        - | 
+------------------------------------------------------------+----------+----------+ 
| Other marketing expenses                                   |    3,708 |    2,352 | 
+------------------------------------------------------------+----------+----------+ 
| Total marketing and sales expenses                         |   10,568 |    7,817 | 
+------------------------------------------------------------+----------+----------+ 
 
Following the acquisition of Salus Futura in July 2009, we integrated both 
companies and restructured top management. This resulted in material redundancy 
payments, but will also lead to significantly lower operating costs in the 
coming years. 
 
11.  Research and development expenses 
+------------------------------------------------------------+----------+----------+ 
|                                                            |     2009 |     2008 | 
+------------------------------------------------------------+----------+----------+ 
| Employee benefit expenses                                  |      265 |       69 | 
+------------------------------------------------------------+----------+----------+ 
| Other research and development costs                       |      138 |       28 | 
+------------------------------------------------------------+----------+----------+ 
| Total research and development expenses                    |      403 |       97 | 
+------------------------------------------------------------+----------+----------+ 
 
Employee benefit expenses increased in 2009 due to less capitalized development 
costs. Number of staff did not increase. Other research and development costs 
included EUR0.1 million contribution to third parties' research projects. 
 
12.  General and administrative expenses 
 
+------------------------------------------------------------+----------+----------+ 
|                                                            |     2009 |     2008 | 
+------------------------------------------------------------+----------+----------+ 
| Employee benefit expenses                                  |    4,392 |    3,455 | 
+------------------------------------------------------------+----------+----------+ 
| Other general and administrative expenses                  |    7,553 |    6,531 | 
+------------------------------------------------------------+----------+----------+ 
| Non-recurring write-down on equity accounted investees     |    1,027 |        - | 
+------------------------------------------------------------+----------+----------+ 
| Non-recurring listing expenses                             |      952 |        - | 
+------------------------------------------------------------+----------+----------+ 
| Total general and administrative expenses                  |   13,924 |    9,986 | 
+------------------------------------------------------------+----------+----------+ 
 
Employee benefit expenses increased EUR0.9 million due to the full year impact of 
the acquired companies in 2008 and investments made in India and France. Other 
general and administrative expenses mainly increased due to the increase of 
depreciation and amortization (EUR+0.7 million). 
 
The non-recurring listing expenses related to the listing of Cryo-Save Group at 
NYSE Euronext Amsterdam at 22 October 2009. The expenses mainly relate to 
advisers fees. 
 
Cryo-Save's associate Cryo-Save Arabia, which operates in the United Arab 
Emirates, saw a significantly decrease in sales during 2009. As a result, the 
Group wrote down EUR1.0 million of receivables due from Cryo-Save Arabia. This 
relates to non-cash fees of EUR0.5 million services regarding the construction of 
the processing and storage facility, a non-cash royalty fee of EUR0.2 million for 
samples processed and stored in Dubai, and a fee of EUR0.3 million for samples 
processed and stored in Belgium processing and storage facility from UAE 
customers. The receivables comprise of EUR0.5 million relating to 2007, EUR0.3 
million to 2008 and EUR0.2 million to 2009. 
 
13.  Employee benefit expenses 
 
+--------------------------------------------------+----------+----------+ 
|                                                  |     2009 |     2008 | 
+--------------------------------------------------+----------+----------+ 
| Salaries and wages                               |    9,665 |    7,308 | 
+--------------------------------------------------+----------+----------+ 
| Social security costs                            |    1,244 |    1,016 | 
+--------------------------------------------------+----------+----------+ 
| Cost of defined contribution plans               |      119 |       74 | 
+--------------------------------------------------+----------+----------+ 
| Share-based payment expenses                     |      266 |      211 | 
+--------------------------------------------------+----------+----------+ 
| Other personnel expenses                         |      223 |      380 | 
+--------------------------------------------------+----------+----------+ 
| Total employee benefit expenses                  |   11,517 |    8,989 | 
+--------------------------------------------------+----------+----------+ 
 
The number of employees, expressed in full-time equivalents, is 250 as at 31 
December 2009 (2008: 196). Full time equivalents (FTEs) increased organically by 
54, mainly reflecting the increase of investments in sales staff in India and 
France. 
 
14. Depreciation and amortization expenses 
 
+--------------------------------------------------+----------+----------+ 
|                                                  |     2009 |     2008 | 
+--------------------------------------------------+----------+----------+ 
| Depreciation of property, plant and equipment    |      999 |      551 | 
+--------------------------------------------------+----------+----------+ 
| Amortization of intangible assets regarding      |    1,223 |    1,077 | 
| acquisitions                                     |          |          | 
+--------------------------------------------------+----------+----------+ 
| Amortization of other intangible assets          |       97 |       16 | 
+--------------------------------------------------+----------+----------+ 
| Total depreciation and amortization expenses     |    2,319 |    1,644 | 
+--------------------------------------------------+----------+----------+ 
 
The increase of depreciation expenses is mainly due to the new processing and 
storage facility in Belgium. The increase of amortization expenses is due to the 
full year impact on amortization of identified assets, such as customer 
relationship, brand name, contracts and order backlog. 
 
15.  Finance income 
 
+--------------------------------------------------+----------+----------+ 
|                                                  |     2009 |     2008 | 
+--------------------------------------------------+----------+----------+ 
| Interest income bank and deposits                |      107 |      789 | 
+--------------------------------------------------+----------+----------+ 
| Currency translation differences                 |       11 |      199 | 
+--------------------------------------------------+----------+----------+ 
| Total finance income                             |      118 |      988 | 
+--------------------------------------------------+----------+----------+ 
 
Interest income mainly comprise of interest on bank deposits. Interest income 
decreased significantly due to a lower cash position in 2009 following the 
acquisition spending in 2008 and lower interest rates. 
 
16.  Finance costs 
 
+------------------------------------------------------------+----------+----------+ 
|                                                            |     2009 |     2008 | 
+------------------------------------------------------------+----------+----------+ 
| Bank charges and other finance costs                       |      280 |      192 | 
+------------------------------------------------------------+----------+----------+ 
| Unwinding of discounted deferred considerations            |      293 |      242 | 
+------------------------------------------------------------+----------+----------+ 
| Interest expense sale and leaseback                        |       90 |        - | 
+------------------------------------------------------------+----------+----------+ 
| Total finance costs                                        |      663 |      434 | 
+------------------------------------------------------------+----------+----------+ 
 
The unwinding of discounted deferred considerations related to three performance 
plans with former shareholders of acquired companies. These costs are non-cash 
items. 
 
The interest expenses related to the sale and leaseback agreement dated 1 
September 2009 of EUR4.3 million at a fixed interest percentage of 5.5% for the 
period of 15 years. 
 
17.  Income tax expense 
 
+------------------------------------------------------------+----------+-------------------+ 
|                                                            |     2009 |              2008 | 
+------------------------------------------------------------+----------+-------------------+ 
| Income tax recognized in profit or loss                    |      431 |               293 | 
+------------------------------------------------------------+----------+-------------------+ 
|                                                            |          |                   | 
+------------------------------------------------------------+----------+-------------------+ 
| Tax expense comprises:                                     |          |                   | 
+------------------------------------------------------------+----------+-------------------+ 
| Current tax expense/(income)                               |    1,476 |               988 | 
+------------------------------------------------------------+----------+-------------------+ 
| Deferred tax expense/(income)                              |    (678) |             (695) | 
+------------------------------------------------------------+----------+-------------------+ 
| Prior year's tax difference                                |    (367) |                 - | 
+------------------------------------------------------------+----------+-------------------+ 
| Total tax expense                                          |      431 |               293 | 
+------------------------------------------------------------+----------+-------------------+ 
|                                                            |          |                   | 
| Reconciliation of the effective tax rate:                  |          |                   | 
+------------------------------------------------------------+----------+-------------------+ 
| Profit before taxation                                     |    1,783 |             2,861 | 
+------------------------------------------------------------+----------+-------------------+ 
| Income tax using the Company's domestic tax rate           |      455 |               730 | 
+------------------------------------------------------------+----------+-------------------+ 
| (Dutch nominal tax rate 2009: 25.5%; 2008: 25.5%)          |          |                   | 
+------------------------------------------------------------+----------+-------------------+ 
|                                                            |          |                   | 
| Tax effect of:                                             |          |                   | 
+------------------------------------------------------------+----------+-------------------+ 
| Effect of tax rates in other countries                     |    (731) |             (538) | 
+------------------------------------------------------------+----------+-------------------+ 
| Non-deductible expenses                                    |      173 |                95 | 
+------------------------------------------------------------+----------+-------------------+ 
| Profits offset with unused tax losses for which no         |          |                   | 
| deferred tax asset                                         |          |                   | 
+------------------------------------------------------------+----------+-------------------+ 
| had been recognized                                        |     (17) |            (128)  | 
+------------------------------------------------------------+----------+-------------------+ 
| Unused tax losses not recognized as deferred tax assets    |      918 |               134 | 
+------------------------------------------------------------+----------+-------------------+ 
| Prior year´s tax difference                                |    (367) |                 - | 
+------------------------------------------------------------+----------+-------------------+ 
| Income tax expense                                         |      431 |               293 | 
+------------------------------------------------------------+----------+-------------------+ 
 
The weighted average tax rate on profits before taxation was 24.4% (2008: 
10.2%). 
 
The positive impact on our effective tax rate of 24.4% from the low tax rate in 
especially Switzerland and the over provision in prior years is almost offset by 
the impact from unused tax losses not recognized as deferred tax assets. 
 
The Company's unused tax losses amount to EUR10.5 million including a 2007 
adjustment of EUR3.9 million (2008: EUR3.9 million excluding the 2007 adjustment of 
EUR3.9 million). Due to the uncertainty of realising these unused tax losses in 
future periods, a deferred tax asset (in any of the above years) has not been 
recognized in respect of those losses. Part of the unused tax losses will expire 
on 31 December 2014 (EUR2.1 million), EUR8.4 million can be compensated 
indefinitely. 
 
Estimates and judgments by management are required in determining the Group's 
provisions for tax liabilities, amongst others corporate income tax and value 
added tax. The calculation of the tax liabilities is based in part of the 
interpretations of applicable tax laws in the jurisdictions in which the Group 
operates. Although the Group believes the tax estimates are reasonable, there is 
no assurance that the final determination of the tax liabilities will not be 
materially different from what is reflected in the statement of income and 
statement of financial position. Should additional taxes be assessed these could 
have a material effect on the Group's results of operation or financial 
condition. 
 
18.  Earnings per share 
 
+------------------------------------------------------------+----------+----------+ 
|                                                            |     2009 |     2008 | 
+------------------------------------------------------------+----------+----------+ 
| Underlying* basic earnings per share (in euro cents)       |     48.4 |     36.0 | 
+------------------------------------------------------------+----------+----------+ 
| Underlying* diluted earnings per share (in euro cents)     |     48.4 |     36.0 | 
+------------------------------------------------------------+----------+----------+ 
|                                                            |          |          | 
+------------------------------------------------------------+----------+----------+ 
| Reported basic earnings per share (in euro cents)          |     14.6 |     27.3 | 
+------------------------------------------------------------+----------+----------+ 
| Reported diluted earnings per share (in euro cents)        |     14.6 |     27.3 | 
+------------------------------------------------------------+----------+----------+ 
 
*Underlying results are adjusted for amortization of identified intangible 
assets,  write down of the receivable from the the Group's associate, Euronext 
listing costs  and restructuring costs. 
 
Pursuant to the passing of the relevant resolution at the Extraordinary General 
Meeting, held on 5 October 2009, the 5:1 share consolidation became effective. 
The comparative 2008 basic and diluted earnings per share have been restated for 
the 5:1 share consolidation. 
 
Basic earnings per share (EPS) are calculated by dividing profit attributable to 
ordinary equity holders of the Company by the weighted average number of 
ordinary shares outstanding during the period. 
 
The calculation of diluted earnings per share is based on the calculation of the 
basic earnings per share, adjusted to allow for the assumed conversion of all 
dilutive share options. 
 
The average market value of ordinary shares during 2009 did exceed the exercise 
price of the share options granted in 2009 only. Hence, the options had a 
dilutive effect, which was not material. 
 
Reconciliation between issued number of shares and weighted average number of 
shares: 
 
+-----------------------------------------------+--------------+-------------+ 
|                                               |         2009 |        2008 | 
+-----------------------------------------------+--------------+-------------+ 
| Issued ordinary shares at 1 January           |   48,195,986 |  48,195,986 | 
+-----------------------------------------------+--------------+-------------+ 
| Effect of share consolidation                 | (38,556,795) |           - | 
+-----------------------------------------------+--------------+-------------+ 
| Shares held in treasury                       |    (409,833) | (1,221,335) | 
+-----------------------------------------------+--------------+-------------+ 
| Weighted average number of shares             |    9,229,358 |  46,974,651 | 
+-----------------------------------------------+--------------+-------------+ 
 
 
Reconciliation between weighted average number of shares and diluted weighted 
average number 
 of shares: 
 
+-----------------------------------------------+------------+------------+ 
|                                               |       2009 |       2008 | 
+-----------------------------------------------+------------+------------+ 
| Weighted average number of shares             |  9,229,358 | 46,974,651 | 
+-----------------------------------------------+------------+------------+ 
| Share options                                 |      7,478 |          - | 
+-----------------------------------------------+------------+------------+ 
| Diluted weighted average number of shares     |  9,236,836 | 46,974,651 | 
+-----------------------------------------------+------------+------------+ 
| Profit attributable to ordinary equity        |      1,352 |      2,568 | 
| holders of the Company                        |            |            | 
+-----------------------------------------------+------------+------------+ 
 
 
19.  Intangible assets 
 
+----------------+-----------+------------+------------+------------+---------+---------+ 
|                |  Goodwill | Identified | Internally |      Other |    2009 |    2008 | 
|                |           | intangible |            | intangible |         |         | 
|                |           |     assets | generated  |     assets |         |         | 
|                |           |            | intangible |            |         |         | 
|                |           |            |            |            |         |         | 
|                |           |            |     assets |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| At 1 January   |           |            |            |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Cost           |   25,947  |     11,978 |        561 |         45 |  38,531 |   1,943 | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Amortization   |         - |    (1,077) |          - |       (16) | (1,093) |       - | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Net book value |           |            |            |            |         |         | 
|                |           |            |            |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| at 1 January   |    25,947 |     10,901 |        561 |         29 |  37,438 |   1,934 | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Movements      |           |            |            |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Translation    |     (109) |       (95) |          - |          - |   (204) |       - | 
| differences    |           |            |            |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Acquisitions   |     2,028 |        100 |          - |          - |   2,128 |  36,188 | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Investments    |         - |          - |        186 |         31 |     217 |     400 | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Deferred       |   (2,893) |          - |          - |          - | (2,893) |       - | 
| considerations |           |            |            |            |         |         | 
| adjustment     |           |            |            |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Amortization   |         - |    (1,223) |       (83) |       (14) | (1,320) | (1,093) | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Total          |     (974) |    (1,218) |        103 |         17 | (2,072) |  35,495 | 
| movements      |           |            |            |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
|                |           |            |            |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| At 31 December |           |            |            |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Cost           |    24,973 |     11,983 |        747 |         76 |  37,779 |  38,531 | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Amortization   |         - |    (2,300) |       (83) |       (30) | (2,413) | (1,093) | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| Net book value |           |            |            |            |         |         | 
|                |           |            |            |            |         |         | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
| at 31 December |    24,973 |      9,683 |        664 |         46 |  35,366 |  37,438 | 
+----------------+-----------+------------+------------+------------+---------+---------+ 
 
Goodwill increased to the Salus Futura acquisition (EUR0.6 million) and the post 
balance sheet date acquisition of the remaining 30% shareholding of Sejtbank and 
Cryo-Save CZ (EUR1.4 million). 
 
The deferred considerations adjustment of goodwill of EUR2.9 million mainly 
related to the cancellation of the earn out liability to former shareholders of 
Sejtbank and Cryo-Save CZ, following the post balance sheet date acquisition of 
the remaining 30% minority shareholding. 
 
The amortization expense is recorded under general and administrative expenses 
in the statement of income. 
 
The impairment test performed in 2009 showed that the recoverable amount for 
each cash-generating unit exceeded the carrying amount, hence no impairment of 
goodwill or identified intangible assets was recognized in 2009 (2008: EUR0). 
 
The net book value of the identified intangible assets of EUR9.7 million (2008: 
EUR10.9 million) represented the value of brand name EUR1.0 million (2008: EUR1.4 
million), customer relationship EUR5.8 million (2008: EUR6.1 million) and contracts 
EUR2.9 million (EUR3.4 million). 
 
Identified intangible assets 
 
The items such as brand name, customer relationship and contracts with 
distributors and insurers concern assets with a limited useful life. The value 
of these identified intangible assets are mainly determined by ongoing strength 
of the brand name, retention rate of satisfied customers and potential customers 
from contracts with hospitals, insurers and diagnostic centers. 
 
Internally generated intangible assets 
 
Internally generated intangible assets arose from the development of the new 
products CryoCordPlus, Cryo-Lip and the Company's website. The capitalized costs 
consist of directly attributable costs of employee benefits, as well as 
materials and services used. Amortization for the new products will begin when 
the developed products are available for sale as intended by management. 
 
Amortization for the website and CryoCordPlus started from May and October 2009 
respectively as the website was officially launched and the service CryoCordPlus 
was widely rolled out in the market. 
In 2009 and 2008 no impairment of these intangible assets was deemed necessary. 
 
Other intangible assets 
Other intangible assets relate mainly to capitalized software licences and is 
amortised in three years. 
In 2009 and 2008 no impairment of these intangibles was deemed necessary. As in 
previous year, no intangible assets have been pledged as security for 
liabilities. 
 
20.  Equity 
 
Share capital and share premium 
 
Authorized shares 
On 8 October 2009 the Company performed a 5:1 share consolidation. As a result 
of the share consolidation the Company´s authorized share capital now comprises 
of 48,000,000 shares with a par value of EUR4,800,000 as per 31 December 2009 
(ordinary shares of EUR0.10 each). 
 
At 31 December 2008, the total authorized share capital consisted of 177,686,250 
shares with a par value of EUR3,553,725 (ordinary shares of EUR0.02 each). 
 
Issued shares 
The total issued ordinary share capital consists per 31 December 2009 of 
9,639,191 shares with a par value of EUR0.10 (31 December 2008 restated: 9,639,191 
shares). 
 
At the Annual General Meeting of Shareholders held on 20 May 2009, it was 
resolved to delegate to the Board of Directors the power (a) to issue shares and 
rights to subscribe for shares in the share capital of the Company to a maximum 
number of 20% of the issued share capital, and (b) to restrict or exclude the 
pre-emptive rights in connection with an issue of such number of shares or 
rights to subscribe for shares, each for a period of 18 months. 
 
Translation reserve 
 
The translation reserve contains exchange rate differences arising from the 
translation of the net investment in foreign operations, and of the related 
hedges. When a foreign operation is sold, exchange differences that were 
recorded in equity prior to the sale are recycled through the income statement 
as part of the gain or loss on divestment. This reserve is not available for 
distribution. 
 
Revaluation reserve 
 
The revaluation reserve relate to the accounting of the 2008 acquisition of 50% 
of the remaining shares of Cryo-Save Balcanica S.A. As part of the purchase 
price allocation, the intangible assets relating to the 50% of the shares 
already owned by Cryo-Save were revalued. Along with the amortization, the 
reserve will be released to retained earnings. This reserve is not available for 
distribution. 
 
Legal reserve 
 
Legal reserve contains appropriations of profits of Group companies which are 
allocated to a legal reserve based on statutory and/or legal requirements. This 
reserve is not available for distribution. 
 
Dividends 
 
In July 2009, the Company distributed a maiden dividend of 1 euro cent for the 
year ended 31 December 2008 (5 euro cent restated for 5:1 share consolidation). 
The total dividend distributed amounted to EUR462,000. 
 
Treasury shares 
 
To cover the dilutive effect of the granted share options in 2007, 2008 and 2009 
under the 2007 and 2009 Share Option Scheme to staff and to fund acquisitions, 
the Group started a share buyback programme in 2007. At 31 December 2009 the 
Group had acquired 424,000 of its own shares in treasury (31 December 2008: 
354,000). Treasury shares are recorded at cost and amounted to EUR3.7 million at 
31 December 2009 (31 December 2008: EUR3.5 million), representing the market price 
on the acquisition date. 
 
At the Extraordinary General Meeting of Shareholders held on 5 October 2009, it 
was resolved to delegate to the Board of Directors the power (a) to repurchase 
shares up to a maximum of 10% of the Company's issued shares as at the date of 
the of the extraordinary general meeting of shareholders, (b) by acquiring 
shares or depository interest; (c) for a purchase price not less than ten euro 
cents and not higher than the highest of either (i) the average closing price 
over the five trading days prior to the date of acquisition on Euronext 
Amsterdam by NYSE Euronext plus a 10% premium or (ii) the average closing price 
over the five trading days prior to the date of acquisition on AIM plus a 10% 
premium; (d) for a period of 18 months. 
 
+---------------------------------------+----------+---------+-------+-------+ 
|                                       |   Number of shares |      Purchase | 
|                                       |                    |         price | 
+---------------------------------------+--------------------+---------------+ 
|                                       |     2009 |    2008 |  2009 |  2008 | 
+---------------------------------------+----------+---------+-------+-------+ 
| Balance at 1 January                  |  354,000 |  31,000 | 3,497 |   435 | 
+---------------------------------------+----------+---------+-------+-------+ 
| Share buyback                         |   70,000 | 323,000 |   167 | 3,062 | 
+---------------------------------------+----------+---------+-------+-------+ 
| Balance at 31 December                |  424,000 | 354,000 | 3,664 | 3,497 | 
+---------------------------------------+----------+---------+-------+-------+ 
 
The purchase price of the share buyback transactions during 2009 ranged from 
187.5 pence to 262.5 pence. 
 
21.  Borrowings 
 
+------------------------------------------------+-----------+--------+ 
|                                                |      2009 |   2008 | 
+------------------------------------------------+-----------+--------+ 
| Borrowings - non-current liabilities           |     3,795 |    111 | 
+------------------------------------------------+-----------+--------+ 
| Borrowings - current liabilities               |       180 |     38 | 
+------------------------------------------------+-----------+--------+ 
| Total borrowings                               |     3,975 |    149 | 
+------------------------------------------------+-----------+--------+ 
 
In March 2009 the Group entered into a sale and leaseback agreement with ING 
Lease Belgium N.V. in relation to the Group´s processing and storage facility in 
Niel, Belgium. Pursuant to the agreement, NG Lease Belgium N.V. purchased the 
facility and agreed to finance its construction for an amount of EUR4.3 million. 
The Group leased the facility for a fixed period of 15 years. Lease instalments 
are paid quarterly in advance commencing on 1 September 2009, and are computed 
on an annuity basis. The interest is fixed for 15 years at 5.5%. The first 
quarterly payment amounted to EUR430,000 followed by quarters of EUR93,000. The 
lease obligation is recognized as financial lease obligation (borrowings). After 
the initial 15-years lease period, the Group has the right to purchase the 
facility from ING Lease Belgium N.V. for 10% of the invested amount (EUR430,000). 
 
22.  Deferred revenue 
 
+------------------------------------------------+-----------+--------+ 
|                                                |      2009 |   2008 | 
+------------------------------------------------+-----------+--------+ 
| Deferred revenue - non-current liabilities     |     6,090 |  4,885 | 
+------------------------------------------------+-----------+--------+ 
| Deferred revenue - current liabilities         |       471 |    389 | 
+------------------------------------------------+-----------+--------+ 
| Total deferred revenue                         |     6,561 |  5,274 | 
+------------------------------------------------+-----------+--------+ 
 
Deferred revenue will be earned as revenue by means of the annual storage over a 
contractually committed 20 years period. The part of deferred revenue that will 
be recognized as revenue within one year, is disclosed under current 
liabilities. 
 
23.  Non-current other liabilities 
 
+------------------------------------------------+---------+----------+ 
|                                                |    2009 |     2008 | 
+------------------------------------------------+---------+----------+ 
| Deferred considerations                        |   2,080 |    5,777 | 
+------------------------------------------------+---------+----------+ 
| Other non-current liabilities                  |      84 |       53 | 
+------------------------------------------------+---------+----------+ 
| Total non-current other liabilities            |   2,164 |    5,830 | 
+------------------------------------------------+---------+----------+ 
 
Deferred considerations relate to three performance plans agreed with former 
owners of acquired entities. The duration of the contracts is 3 years. 
 
24.  Share-based payments 
 
In 2009 the Group recognized EUR0.3 million share-based payment costs, relating to 
three option plans issued in 2007, 2008 and 2009 respectively (2008: EUR0.2 
million). 
 
Share option scheme 
At 23 April 2009 options were granted for 67,000 ordinary shares in Cryo-Save 
Group N.V. The Company granted 35,000 options to Directors of the Company and 
32,000 options to certain other employees of the Company all at an exercise 
price of 279 pence per share. 
 
Share options 
 
+----------------------------+----+--+----------+----------+----------+---------+ 
|                            |    |  |    Share option plans for the years:     | 
+----------------------------+----+--+------------------------------------------+ 
|                            |    |  |     2009 |     2008 |     2007 |   Total | 
+----------------------------+----+--+----------+----------+----------+---------+ 
| Outstanding at 1 January   |    |  |        - |   68,000 |   68,000 | 136,000 | 
| 2009                       |    |  |          |          |          |         | 
+----------------------------+----+--+----------+----------+----------+---------+ 
| Conditionally awarded      |    |  |   67,000 |        - |        - |  67,000 | 
+----------------------------+----+--+----------+----------+----------+---------+ 
| Vested                     |    |  |        - |        - |        - |       - | 
+----------------------------+----+--+----------+----------+----------+---------+ 
| Forfeited                  |    |  |    8,000 |   30,000 |   15,000 |  53,000 | 
+----------------------------+----+--+----------+----------+----------+---------+ 
| Outstanding at 31 December |    |  |   59,000 |   38,000 |   53,000 | 150,000 | 
| 2009                       |    |  |          |          |          |         | 
+----------------------------+----+--+----------+----------+----------+---------+ 
| End of period              |    |  |     2019 |     2018 |     2017 |         | 
+----------------------------+----+--+----------+----------+----------+---------+ 
| Exercise price in pence    |    |  |  GBP2.79 | GBP10.50 | GBP11.05 |         | 
+----------------------------+----+--+----------+----------+----------+---------+ 
 
The former Chief Executive Officer, Rob Koremans, left the Group per 31 July 
2009. Mr. Koremans held 20,000 options granted in 2009 which were exercisable 
until 30 January 2010. The options granted to Mr. Koremans in 2007 (15,000) and 
2008 (20,000) lapsed as per 31 July 2009 when he left the Company. The remainder 
forfeited share options related to senior managers that left the Company. 
 
The fair market value of each conditionally awarded share in 2009 under the 
Share Option Scheme was GBP1.86 (Share option plan 2008: GBP4.65, Share option 
plan 2007: GBP4.74), as determined by an outside consulting firm. 
 
 
Shareholding of the Directors 
 
The Directors hold the following interest in the Company as at 31 December 2009: 
 
+------------------------------------------------------------+-----------+-----------+ 
|                                                            |      2009 |      2008 | 
+------------------------------------------------------------+-----------+-----------+ 
| M.J. Waeterschoot*                                         | 1,792,704 | 1,850,334 | 
+------------------------------------------------------------+-----------+-----------+ 
| A.P. van Tulder                                            |    13,000 |     7,000 | 
+------------------------------------------------------------+-----------+-----------+ 
| J.P.G. Goossens*                                           | 1,612,127 | 1,612,127 | 
+------------------------------------------------------------+-----------+-----------+ 
| W.A.A. van Pottelberge                                     |    16,210 |    11,210 | 
+------------------------------------------------------------+-----------+-----------+ 
 
* The interest of these Directors includes the interests of their immediate 
families and any other persons connected with them, and of companies of which 
the Directors are a controlling shareholder. 
 
25.  Events after the reporting period 
 
Acquisition remaining 30% shares of Sejtbank and Cryo-Save CZ 
At 25 February 2010, the Company acquired the remaining 30% minority 
shareholding of its Hungarian subsidiary, Sejtbank Egeszegugyi Szolgaltato 
Korlatolt Felelossegu Tarsasag ('Sejtbank') and Cryo-Save CZ (formerly Archiv 
Bunek s.r.o.), for a total cash consideration of EUR1.4 million. 
 
 
 
The Annual Report 2009 will be available on the Company's website 
www.cryo-savegroup.com  in April 2010. 
 
 
+-----------------------+--------------------------------------------+ 
| Contact details       | For more information on Cryo-Save visit    | 
+-----------------------+--------------------------------------------+ 
| Cryo-Save Group N.V.  | www.cryo-savegroup.com, or contact         | 
|                       | Investor Relations                         | 
+-----------------------+--------------------------------------------+ 
| IJsselkade 8          | at ir@cryo-save.com                        | 
+-----------------------+--------------------------------------------+ 
| 7201 HB Zutphen       |                                            | 
+-----------------------+--------------------------------------------+ 
| The Netherlands       |                                            | 
+-----------------------+--------------------------------------------+ 
| +31 (0)575 548998     |                                            | 
+-----------------------+--------------------------------------------+ 
 
 
 
This information is provided by RNS 
            The company news service from the London Stock Exchange 
   END 
 
 FR QLLBLBXFXBBQ 
 

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