GeneThera Releases Results From Initial Animal Tests of E.Coli O157:h7 Vaccine Amid News of Increase of E.Coli Discoveries in Be
17 11월 2008 - 11:00PM
PR Newswire (US)
WHEAT RIDGE, Colo., Nov. 17 /PRNewswire-FirstCall/ -- GeneThera,
Inc. (Pink Sheets: GTHR), today released information about its
E.Coli O157:H7 vaccine. The vaccine consists of Live Attenuated
Bacterial Vaccine to Reduce or Inhibit Carriage and Shedding of
Enterohemorrihagic Escherichia Coli in Cattle. This vaccine was
developed for use against Shiga toxin-producing E.Coli (STEC) in
cattle. This strategy is to construct mutants that have deletion in
the genes responsible for E.Coli O157:H7 toxicity. Along with the
mutation to inactivate the Shiga toxin gene, the modified bacteria
also carry a mutation that inactivates genes that allows the growth
of the E.Coli 0157:H7 in the cow intestine. These modifications
will greatly attenuate bacterial virulence. According to Dr. Tony
Milici MD, PhD, GeneThera's Chairman and CEO, "Initial experimental
animal trials in both challenged rabbits and mice showed a
reduction of 99% E.Coli shedding in vaccinated animals when
compared with control animals." GeneThera is aggressively pursuing
a distribution partner to assist in bringing this vaccine/therapy
technology to market. Their efforts are bolstered by the recent
report from the Washington Post dated November 10, which stated
"...There were 21 beef recalls in the United States in 2007,
compared with eight the year before. About a third of the recalls
were prompted by reports of human illness, while none of the 2006
recalls were. This year, meat inspectors from the U.S. Department
of Agriculture have continued to see more contaminated beef
samples. Through mid-October, they had recorded 50 percent more
than at the same time last year." Officials have assumed that these
numbers reflect an overall increase in the prevalence of the E.Coli
strain in cattle, but no one has been able to explain why the
dangerous bacteria have become more abundant. Given the recent
emergence of a similar product from a competitor, we feel that now
is the time to begin a full court press to bring our vaccine to the
forefront of the agricultural and food industries. We believe very
strongly that our vaccine is a far superior product to that of our
competition. To help bring awareness to GeneThera and its efforts,
we have engaged two very well known multimedia investor relations
firms, Wallst.net and StockBully.com. Both firms are multimedia
investor relation's sources that seek out promising and mostly
undiscovered companies in the market place and enable their clients
to utilize multimedia marketing to gain exposure via the
information highway. "GeneThera is a fantastic company with a solid
business model and superior management. We are extremely pleased to
have the opportunity to assist them in their effort to increase
investor awareness in the financial market," said Adam Ben-Evi,
President of Stockbully.com. About E.Coli O157:h7 There are a
variety of Escherichia coli bacteria present in nature. They are
usually found in the intestines of healthy humans and healthy
animals. Even though these bacteria offer beneficial properties,
there are those variations, or strains that are pathogenic (have
the ability to cause disease). Escherichia coli 0157:H7 is one
particular strain that is "... an emerging cause of food borne
illness ..." Symptoms such as bloody diarrhea and abdominal cramps
may be observed or no such symptoms may appear. The elderly and
children under five years old are highly susceptible to Hemolytic
Uremic Syndrome, a disease in which red blood cells are destroyed
and kidneys fail. According to the CDC "...there may be about
70,000 infections with E. Coli O157:H7 each year in the United
States. We can only estimate because we know that many infected
people do not seek medical care, many do not submit a stool
specimen for testing, and many labs do not test for STEC. The
bacteria that make these toxins are called 'Shiga toxin producing'
E. coli, or STEC for short." Shiga toxin is one of the most potent
toxins known to man, so much so that the Centers for Disease
Control and Prevention (CDC) lists it as a potential bioterrorist
agent (CDC, n.d.). ABOUT GENETHERA, INC. GeneThera, Inc. is a
molecular biotechnology company located in Wheat Ridge, Colorado.
The Company provides genetic diagnostic solutions for the
veterinary and agricultural industries with future plans to include
the healthcare industry. The Company's proprietary diagnostic
solution is based on a genetic expression assay, GES(TM), a
protocol designed to function on a highly automated Fluorogenic PCR
platform. This platform enables GeneThera to offer tests that are
presently not available from other technologies. The GES is
designed for a host of individual diseases, the current priorities
being Mad Cow disease, Chronic Wasting Disease, E. coli 0157:H7 and
Johne's disease, all diseases affecting cattle worldwide. For more
information, contact Dr. Tony Milici at 303-463-6371 or Al
Goldsmith of The Goldsmith Group LLC at 303-838-4370. This press
release contains forward-looking statements, which are made
pursuant to the Safe-Harbor provisions of the Private Securities
Litigation Reform Act of 1995. Words such as "intends," "believes,"
and similar expressions reflecting something other than historical
fact are intended to identify forward-looking statements, but are
not the exclusive means of identifying such statements. These
forward-looking statements involve a number of risks and
uncertainties, including the timely development and market
acceptance of products and technologies, the ability to secure
additional sources of finance, the ability to reduce operating
expenses, and other factors described in the Company's filings with
the Securities and Exchange Commission. The actual results that the
Company achieves may differ materially from any forward-looking
statement due to such risks and uncertainties. The Company
undertakes no obligation to revise or update any forward-looking
statements in order to reflect events or circumstances that may
arise after the date of this release. Dr. Tony Milici 303-463-6371
Goldsmith Group 303-838-4370 JR Dopkin & Associates
516-884-3200 DATASOURCE: GeneThera, Inc. CONTACT: Dr. Tony Milici,
+1-303-463-6371; or Goldsmith Group, +1-303-838-4370; or JR Dopkin
& Associates, +1-516-884-3200, all for GeneThera, Inc.
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