TRMS Trimeris (MM)

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CUSIP No. 896263100 13G Page 2 of 7 Pages
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 1. NAMES OF REPORTING PERSONS
 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

 PERCEPTIVE ADVISORS LLC

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 2. CHECK THE APPROPRIATE BOX IF A GROUP* (a) [ ]
 (b) [ ]
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 3. SEC USE ONLY



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 4. CITIZENSHIP OR PLACE OF ORGANIZATION

 DELAWARE, UNITED STATES OF AMERICA

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------------------- ---- -------------------------------------------- --------------------------------------------
 NUMBER OF
 SHARES 5. SOLE VOTING POWER 0
------------------- ---- -------------------------------------------- --------------------------------------------
 BENEFICIALLY
 OWNED BY 6. SHARED VOTING POWER 2,261,500
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 EACH
 REPORTING 7. SOLE DISPOSITIVE POWER 0
------------------- ---- -------------------------------------------- --------------------------------------------
 PERSON WITH:
 8. SHARED DISPOSTIVE POWER 2,261,500
------------------- ---- -------------------------------------------- --------------------------------------------
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 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,261,500
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 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
 (SEE INSTRUCTIONS) [ ]
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 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 10.1%
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 12. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) IA
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CUSIP No. 896263100 13G Page 3 of 7 Pages
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 13. NAMES OF REPORTING PERSONS
 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

 JOSEPH EDELMAN

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 14. CHECK THE APPROPRIATE BOX IF A GROUP* (a) [ ]
 (b) [ ]
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 15. SEC USE ONLY

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 16. CITIZENSHIP OR PLACE OF ORGANIZATION

 UNITED STATES OF AMERICA

--------- --------------------------------------------------------------------------------------------------------
------------------- ---- -------------------------------------------- --------------------------------------------
 NUMBER OF
 SHARES 17. SOLE VOTING POWER 0
------------------- ---- -------------------------------------------- --------------------------------------------
 BENEFICIALLY
 OWNED BY 18. SHARED VOTING POWER 2,261,500
------------------- ---- -------------------------------------------- --------------------------------------------
 EACH
 REPORTING 19. SOLE DISPOSITIVE POWER 0
------------------- ---- -------------------------------------------- --------------------------------------------
 PERSON WITH:
 20. SHARED DISPOSTIVE POWER 2,261,500
------------------- ---- -------------------------------------------- --------------------------------------------
--------- ------------------------------------------------------------------------- ------------------------------

 21. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,261,500
--------- ------------------------------------------------------------------------- ------------------------------
--------- --------------------------------------------------------------------------------------------------------

 22. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
 (SEE INSTRUCTIONS) [ ]
--------------------------------------------------------------------------------------------------------

--------- ------------------------------------------------------------------------- ------------------------------

 23. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 10.1%
--------- ------------------------------------------------------------------------- ------------------------------

 24. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) IN
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CUSIP No. 896263100 13G Page 4 of 7 Pages
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ITEM 1.
(a) Name of Issuer: TRIMERIS, INC.

 2530 MERIDIEN PARKWAY, 2ND FLOOR
(b) Address of Issuer's Principal Executive Offices: DURHAM, NC 27713

 ITEM 2. THIS SCHEDULE 13G (THE
 "SCHEDULE") IS BEING FILED WITH RESPECT
 TO SHARES OF COMMON STOCK (AS DEFINED
 BELOW) OF TRIMERIS, INC. (THE "ISSUER")
(a) Name of Person Filing: WHICH ARE BENEFICIALLY OWNED BY
 PERCEPTIVE ADVISORS LLC AND JOSEPH
 EDELMAN (TOGETHER, THE "REPORTING
 PERSONS"). SEE ITEM 4 BELOW.

(b) Address of Principal Business
 Office or, if none, Residence: 499 PARK AVENUE, 25TH FLOOR
 NEW YORK, NY 10022

 PERCEPTIVE ADVISORS LLC IS A DELAWARE
(c) Citizenship: LIMITED LIABILITY COMPANY AND JOSEPH
 EDELMAN IS A UNITED STATES CITIZEN.

(d) Title of Class of Securities: COMMON STOCK


(e) CUSIP Number: 896263100


ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO ss.ss.240.13D-1(B) OR
240.13D-2(B) OR (C), CHECK WHETHER THE PERSON FILING IS A:

(a) [ ] Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

(b) [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

(c) [ ] Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C.
78c).

(d) [ ] Investment company registered under section 8 of the Investment Company
Act of 1940 (15 U.S.C 80a-8).

(e) [X] An investment adviser in accordance with ss.240.13d-1(b)(1)(ii)(E);

(f) [ ] An employee benefit plan or endowment fund in accordance with
ss.240.13d-1(b)(1)(ii)(F);

(g) [ ] A parent holding company or control person in accordance with ss.
240.13d-1(b)(1)(ii)(G);

(h) [ ] A savings associations as defined in Section 3(b) of the Federal Deposit
Insurance Act (12 U.S.C. 1813);

(i) [ ] A church plan that is excluded from the definition of an investment
company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C.
80a-3);

(j) [ ] Group, in accordance with ss.240.13d-1(b)(1)(ii)(J).

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CUSIP No. 896263100 13G Page 5 of 7 Pages
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ITEM 4. OWNERSHIP.


Provide the following information regarding the aggregate number and percentage
of the class of securities of the issuer identified in Item 1.

 The Reporting Persons beneficially own
 2,261,500 shares of Common Stock held by a
(a) Amount beneficially owned: private investment fund to which Perceptive
 Advisors LLC serves as the investment
 manager. Mr. Edelman is the managing member
 of Perceptive Advisors LLC.

 The beneficial ownership of 10.1% is based on
 the sum of 22,399,649 shares of Common Stock
 issued and outstanding as of June 13, 2011 as
(b) Percent of class: reflected on the Issuer's Agreement and Plan
 of Merger and Reorganization as well as in
 the Issuer's 10Q of May 13, 2011.

(c) Number of shares as to which the person has:

(i) Sole power to vote or to direct the vote: 0

(ii) Shared power to vote or to direct the vote: 2,261,500

(iii) Sole power to dispose or to direct the disposition of: 0

(iv) Shared power to dispose or to direct the disposition of: 2,261,500


ITEM 5 Ownership of Five Percent or Less of a Class

If this statement is being filed to report the fact that as of the date hereof
the reporting person has ceased to be the beneficial owner of more than five
percent of the class of securities, check the following: [_].

ITEM 6 Not Applicable

Filing of this statement by the Reporting Persons shall not be deemed an
admission that they beneficially own the securities reported herein. The
Reporting Persons expressly disclaim beneficial ownership of all securities
reported herein.

ITEM 7. Identification and Classification of the Subsidiary which Acquired the
Security Being Reported on by the Parent Holding Company or Control Person.

Not applicable.

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CUSIP No. 896263100 13G Page 6 of 7 Pages
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ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

Not applicable.

ITEM 9. NOTICE OF DISSOLUTION OF GROUP.

Not applicable.

ITEM 10. CERTIFICATION

 The following certification shall be included if the
 statement is filed pursuant to ss.240.13d-1(b):

 By signing below I certify that, to the best of my
 knowledge and belief, the securities referred to above
 were acquired and are held in the ordinary course of
 (a) business and were not acquired and are not held for the
 purpose of or with the effect of changing or
 influencing the control of the issuer of the securities
 and were not acquired and are not held in connection
 with or as a participant in any transaction having that
 purpose or effect. [X]

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CUSIP No. 896263100 13G Page 7 of 7 Pages
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 SIGNATURE


 After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

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July 29, 2011
Date

PERCEPTIVE ADVISORS LLC

/s/ Joseph Edelman
Signature

Joseph Edelman/Managing Member
Name/Title
July 29, 2011
Date

/s/ Joseph Edelman
Signature

Joseph Edelman
Name/Title

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The original statement shall be signed by each person on whose behalf the
statement is filed or his authorized representative. If the statement is signed
on behalf of a person by his authorized representative other than an executive
officer or general partner of the filing person, evidence of the
representative's authority to sign on behalf of such person shall be filed with
the statement, provided, however, that a power of attorney for this purpose
which is already on file with the Commission may be incorporated by reference.
The name and any title of each person who signs the statement shall be typed or
printed beneath his signature.

NOTE: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See ss.240.13d-7 for other
parties for whom copies are to be sent.

ATTENTION: INTENTIONAL MISSTATEMENTS OR OMISSIONS OF FACT CONSTITUTE FEDERAL
CRIMINAL VIOLATIONS (SEE 18 U.S.C. 1001)