FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Keyes Jeffry R.
2. Issuer Name and Ticker or Trading Symbol

Quantum-Si Inc [ QSI ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Chief Financial Officer
(Last)          (First)          (Middle)

C/O QUANTUM-SI INCORPORATED, 530 OLD WHITFIELD STREET
3. Date of Earliest Transaction (MM/DD/YYYY)

5/15/2023
(Street)

GUILFORD, CT 06437
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)        (State)        (Zip)
Rule 10b5-1(c) Transaction Indication
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (right to buy) $1.42 5/15/2023  A   1000000     (1)5/15/2033 Class A Common Stock 1000000 $0 1000000 D  
Stock Option (right to buy) $1.42 5/15/2023  A   500000     (2)5/15/2033 Class A Common Stock 500000 $0 500000 D  
Stock Option (right to buy) $1.42 5/15/2023  A   500000     (3)5/15/2033 Class A Common Stock 500000 $0 500000 D  

Explanation of Responses:
(1) The shares underlying this option vest as to 25% on June 30, 2024, with the remainder vesting in 36 equal monthly installments at the end of each month thereafter, subject to Mr. Keyes' continued service through the applicable vesting date.
(2) The shares underlying this option vest in full if within one year of May 15, 2023 the closing price of the Issuer's Class A common stock is at least $10.00 (as adjusted) for 20 out of 30 consecutive trading days, subject to Mr. Keyes' continued service through the vesting date.
(3) The shares underlying this option vest in full if within three years of May 15, 2023 the closing price of the Issuer's Class A common stock is at least $20.00 (as adjusted) for 20 out of 30 consecutive trading days, subject to Mr. Keyes' continued service through the vesting date.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Keyes Jeffry R.
C/O QUANTUM-SI INCORPORATED
530 OLD WHITFIELD STREET
GUILFORD, CT 06437


Chief Financial Officer

Signatures
/s/ Christian LaPointe, Ph.D., Attorney-in-Fact5/16/2023
**Signature of Reporting PersonDate


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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