By Chris Wack


Argenx shares were up 30% to $492.01 Monday after the immunology company said it saw positive topline results from its study with biopharmaceutical company Zai Lab evaluating Vyvgart Hytrulo, or efgartigimod alfa and hyaluronidase-qvfc, in adults with chronic inflammatory demyelinating polyneuropathy.

Argenx stock hit its 52-week high of $498.63 earlier in the session and is up 35% over the past 12 months. Zai Lab shares were up 8% to $30.17.

The companies said the study met its primary endpoint, demonstrating a significantly lower risk of relapse with Vyvgart Hytrulo compared with placebo.

The study showed that the safety and tolerability profile was consistent with the confirmed safety profile of Vyvgart, and 91% of eligible patients continued to the next phase of the open-label extension study.

The most frequent treatment-related adverse event was injection site reactions, which occurred in a lower percentage of patients than previous Vyvgart Hytrulo trials. All injection site reactions were mild to moderate and resolved over time.


Write to Chris Wack at


(END) Dow Jones Newswires

July 17, 2023 10:49 ET (14:49 GMT)

Copyright (c) 2023 Dow Jones & Company, Inc.
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