PreSCD II Registry Shows ICDs Lead to 44 Percent Reduction in Mortality for Heart Attack Survivors
01 9월 2009 - 7:00PM
PR Newswire (US)
NATICK, Mass. and BARCELONA, Sept. 1 /PRNewswire-FirstCall/ --
Boston Scientific Corporation (NYSE:BSX) today announced long-term
data from the Prevention of Sudden Cardiac Death II registry
(PreSCD II). The results found that implantable cardioverter
defibrillators (ICDs) were associated with a 44 percent reduction
in all cause mortality (p=0.053) when implanted in patients
following myocardial infarction (heart attack). The mortality
reduction trend was also observed in high-risk patients with
severely reduced heart function. Analysis of the data was presented
by Professor Heinz Voller, M.D., Klinikum am See, Ruedersdorf,
Germany at the annual European Society of Cardiology (ESC) Congress
in Barcelona. Heart attack survivors have an increased risk for
sudden cardiac death, and patients with impaired left ventricular
function in particular benefit from protection by an ICD. Major
clinical trials such as MADIT II suggest that ejection fraction --
a measure of the heart's pumping capacity -- should be used to
characterize risk and determine which patients should receive an
ICD. Data from PreSCD II revealed that within the highest risk
subgroup (ejection fraction